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Compressive strength (CS) of concrete is a key quality factor that is being monitored continuously in all construction projects which use huge quantity of concrete throughout the world. Engineers need to be open minded with the attitude of lifelonglearning to upskill with the ever-evolving softwareand hardware technologies. Seven day and twenty-eight-day compressive strengths of concrete samples with varied amounts of cement, blast furnace slag, fly ash, water, super plasticizer, coarse aggregate, and fine aggregate are studied. Multiple Linear Regression (MLR) models are fitted for this data in Microsoft Excel. Artificial Neural Networks (ANNs) in RStudio are developed for this data. The performances of both methods are compared. This paper takes care of Goal 12 of United Nations Sustainable Development of ensuring sustainable consumption and production patterns as environmentally degrading materials (flyash and blast furnace slag) are used. [ABSTRACT FROM AUTHOR]