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Your search keyword '"Bupropion metabolism"' showing total 29 results

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29 results on '"Bupropion metabolism"'

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1. Effect of honokiol on cytochrome P450 and UDP-glucuronosyltransferase enzyme activities in human liver microsomes.

2. Characterization of marmoset CYP2B6: cDNA cloning, protein expression and enzymatic functions.

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3. Quantitative prediction of CYP2B6 induction by estradiol during pregnancy: potential explanation for increased methadone clearance during pregnancy.

4. CYP2B6 and bupropion's smoking-cessation pharmacology: the role of hydroxybupropion.

5. Inhibition of bupropion metabolism by selegiline: mechanism-based inactivation of human CYP2B6 and characterization of glutathione and peptide adducts.

6. Effects of the CYP2B6*6 allele on catalytic properties and inhibition of CYP2B6 in vitro: implication for the mechanism of reduced efavirenz metabolism and other CYP2B6 substrates in vivo.

7. Effect of CYP2B6*6 and CYP2C19*2 genotype on chlorpyrifos metabolism.

8. Polymorphic variants of cytochrome P450 2B6 (CYP2B6.4-CYP2B6.9) exhibit altered rates of metabolism for bupropion and efavirenz: a charge-reversal mutation in the K139E variant (CYP2B6.8) impairs formation of a functional cytochrome p450-reductase complex.

9. Comparison of in vitro metabolism of ticlopidine by human cytochrome P450 2B6 and rabbit cytochrome P450 2B4.

10. The use of isolated enterocytes to study Phase I intestinal drug metabolism: validation with rat and pig intestine.

11. Drug interaction study between bupropion and ticlopidine in male CF-1 mice.

12. Effects of pregnane X receptor (NR1I2) and CYP2B6 genetic polymorphisms on the induction of bupropion hydroxylation by rifampin.

13. The in vitro metabolism of bupropion revisited: concentration dependent involvement of cytochrome P450 2C19.

14. Inhibition of human CYP2B6-catalyzed bupropion hydroxylation by Ginkgo biloba extract: effect of terpene trilactones and flavonols.

15. Artemisinin--a possible CYP2B6 probe substrate?

16. Induction of cytochrome P450 2B6 activity by the herbal medicine baicalin as measured by bupropion hydroxylation.

17. Measurement of in vitro cytochrome P450 2B6 activity.

18. Efavirenz induces CYP2B6-mediated hydroxylation of bupropion in healthy subjects.

19. Stereoselective metabolism of bupropion by cytochrome P4502B6 (CYP2B6) and human liver microsomes.

20. Effect of commonly used organic solvents on the kinetics of cytochrome P450 2B6- and 2C8-dependent activity in human liver microsomes.

21. CYP2B6 genotype alters abstinence rates in a bupropion smoking cessation trial.

22. Cytochrome P450 2B6 activity as measured by bupropion hydroxylation: effect of induction by rifampin and ethnicity.

23. Inhibition of human CYP2B6 by N,N',N''-triethylenethiophosphoramide is irreversible and mechanism-based.

24. Selective inhibition of CYP2B6-catalyzed bupropion hydroxylation in human liver microsomes in vitro.

25. Potent mechanism-based inhibition of human CYP2B6 by clopidogrel and ticlopidine.

26. Inhibition of cytochrome P450 2B6 activity by hormone replacement therapy and oral contraceptive as measured by bupropion hydroxylation.

27. Ritonavir, efavirenz, and nelfinavir inhibit CYP2B6 activity in vitro: potential drug interactions with bupropion.

28. CYP2B6 mediates the in vitro hydroxylation of bupropion: potential drug interactions with other antidepressants.

29. Validation of bupropion hydroxylation as a selective marker of human cytochrome P450 2B6 catalytic activity.