Search

A series of 1,2- and 1,4-dihydroquinolines has been successfully prepared. The Pd-catalyzed intramolecular N-arylation of Z-enamines, formally prepared by the Horner–Wadsworth–Emmons olefination, proceeded efficiently to furnish the cyclized products. Depending on the cyclization conditions, substituted 1,4-dihydroquinolines and further isomerized 1,2-dihydroquinolines were independently obtained in high yields with an excellent control of isomerization of the double bond. [ABSTRACT FROM AUTHOR]

A series of 1,2- and 1,4-dihydroquinolines is prepared by Pd-catalyzed intramolecular N-arylation of Z-enamines, formally prepared by the Horner-Wadsworth-Emmons olefination. [ABSTRACT FROM AUTHOR]

The article presents chemical equations related to the article "N-Arylation of Sterically Hindered NH-Nucleophiles: Copper-Mediated Syntheses of Diverse N-Arylindole-2-carboxylates" by Jinyong Lee published in the "Synthesis" in 2015.