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It has been suggested that time at a high fraction (%) of maximal oxygen uptake (VO 2max ) plays a decisive role for adaptations to interval training. Yet, no study has, to date, measured the % of VO 2max during all interval sessions throughout a prolonged training intervention and subsequently related it to the magnitude of training adaptations. Thus, the present study aimed to investigate the relationship between % of VO 2max achieved during an interval training intervention and changes in endurance performance and its physiological determinants in well-trained cyclists. Twenty-two cyclists (VO 2max 67.1 (6.4) mL·min -1  ·kg -1 ; males, n = 19; females, n = 3) underwent a 9-week interval training intervention, consisting 21 sessions of 5 × 8-min intervals conducted at their 40-min highest sustainable mean power output (PO). Oxygen uptake was measured during all interval sessions, and the relationship between % of VO 2max during work intervals and training adaptations were investigated using linear regression. A performance index was calculated from several performance measures. With higher % of VO 2max during work intervals, greater improvements were observed for maximal PO during the VO 2max test (R 2 adjusted  = 0.44, p = 0.009), PO at 4 mmol·L -1 [blood lactate] (R 2 adjusted  = 0.25, p = 0.035), the performance index (R 2 adjusted  = 0.36, p = 0.013), and VO 2max (R 2 adjusted  = 0.54, p = 0.029). Other measures, such as % of maximal heart rate, were related to fewer outcome variables and exhibited poorer session-to-session repeatability compared to % of VO 2max . In conclusion, improvements in endurance measures were positively related to the % of VO 2max achieved during interval training. Percentage of VO 2max was the measure that best reflected the magnitude of training adaptations., (© 2024 The Author(s). European Journal of Sport Science published by Wiley‐VCH GmbH on behalf of European College of Sport Science.)

Altitude training is a cornerstone for endurance athletes for improving blood variables and performance, with optimal effects observed at ∼2,300-2,500 meters above sea level (m.a.s.l.). However, elite cyclists face challenges such as limited access to such altitudes, inadequate training facilities, and high expenses. To address these issues, a novel method involving daily exposure to carbon monoxide (CO) has been proposed to amplify altitude training adaptations at suboptimal altitudes. Thirty-one male cyclists were assigned to three groups: Live-High Train-High with CO inhalation (LHTH CO ), Live-High Train-High (LHTH), and Live-Low Train-Low (LLTL). The LHTH CO group underwent CO inhalation twice daily in the afternoon/evening to elevate carboxyhemoglobin concentration to ∼10%. Hematological variables, in vivo muscle oxidative capacity, and physiological indicators of cycling performance were assessed before and after a 3-week altitude training camp at 2,100 m.a.s.l. LHTH CO demonstrated a larger increase in hemoglobin mass (Hb mass ) compared to both LHTH and LLTL. Although there were no statistical differences between LHTH CO and LHTH in submaximal and maximal performance measures, LHTH CO displayed greater improvements in 1-min maximal power output during incremental testing (W max ), power output at lactate threshold, and maximal oxygen consumption (V̇o 2max ) compared to LLTL. LHTH demonstrated a larger improvement than LLTL in W max and V̇o 2max , with no group differences in Hb mass or submaximal measures. Muscle oxidative capacity did not differ between groups. These findings suggest that combining moderate-altitude training with daily CO inhalation promotes hematological adaptations more effectively than moderate altitude alone and enhances cycling performance metrics in cyclists more than sea-level training. NEW & NOTEWORTHY Three weeks of training at moderate altitude with exposure to low doses of CO can significantly enhance hematological adaptations in elite cyclists compared to moderate-altitude training alone. Cycling performance determinants improved more with CO inhalation at moderate altitude compared to sea-level training, whereas there were no differences in submaximal and maximal performance measures compared to moderate-altitude training alone. This study highlights the potential of CO supplementation as an effective adjunct to altitude training regimens.

Purpose and Methods: To test whether heat training performed as 5 × 50-min sessions per week for 5 wk in a heat chamber (CHAMBER) or while wearing a heat suit (SUIT), in temperate conditions, increases hemoglobin mass (Hb mass ) and endurance performance in elite cyclists, compared with a control group (CON-1). Furthermore, after the 5-wk intervention, we tested whether three sessions per week for 3 wk with heat suit (SUIT main ) would maintain Hb mass elevated compared with athletes who returned to normal training (HEAT stop ) or who continued to be the control group (CON-2)., Results: During the initial 5 wk, SUIT and CHAMBER increased Hb mass (2.6% and 2.4%) to a greater extent than CON-1 (-0.7%; both P < 0.01). The power output at 4 mmol·L -1 blood lactate and 1-min power output ( Wmax ) improved more in SUIT (3.6% and 7.3%, respectively) than CON-1 (-0.6%, P < 0.05; 0.2%, P < 0.01), whereas this was not the case for CHAMBER (1.4%, P = 0.24; 3.4%, P = 0.29). However, when SUIT and CHAMBER were pooled this revealed a greater improvement in a performance index (composed of power output at 4 mmol·L -1 blood lactate, Wmax , and 15-min power output) than CON-1 (4.9% ± 3.2% vs 1.7% ± 1.1%, respectively; P < 0.05). During the 3-wk maintenance period, SUIT main induced a larger increase in Hb mass than HEAT stop (3.3% vs 0.8%; P < 0.05), which was not different from the control (CON-2; 1.6%; P = 0.19), with no differences between HEAT stop and CON-2 ( P = 0.52)., Conclusions: Both SUIT and CHAMBER can increase Hb mass , and pooling SUIT and CHAMBER demonstrates that heat training can increase performance. Furthermore, compared with cessation of heat training, a sustained increase in Hb mass was observed during a subsequent 3-wk maintenance period, although the number of weekly heat training sessions was reduced to 3., (Copyright © 2022 by the American College of Sports Medicine.)