1. Acenocoumarol as an alternative anticoagulant in a patient with warfarin‐related nephropathy.
- Author
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Behera, Sapan Kumar, Xavier, Alphienes Stanley, Selvarajan, Sandhiya, Munuswamy, Hemachandren, Haridasan, Satish, and Srinivas, Bheemanathi Hanuman
- Subjects
RHEUMATIC heart disease ,ATRIAL fibrillation ,ANTICOAGULANTS ,WARFARIN ,KIDNEY diseases ,DRUG side effects ,PATIENTS - Abstract
Adverse Event: Warfarin‐related nephropathy. Drug Implicated: Warfarin. The Patient: A 31‐year‐old female, managed with warfarin for rheumatic heart disease with atrial fibrillation. Evidence that Links the Drug to the Event: There were no alternative causes of nephropathy that could have caused the adverse event in this patient. Management: Shifting the drug from warfarin to acenocoumarol. Mechanism: Difference in renal elimination between warfarin and acenocoumarol. Implication for Therapy: Clinicians should be aware of this rare adverse effect of warfarin, and acenocoumarol can be considered as an alternative therapy for this condition. Hypotheses to be Tested: Further prospectively designed studies are needed to consider acenocoumarol as an alternative therapy in warfarin‐related nephropathy. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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