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Background: Auditory deprivation due to otitis media with effusion(OME) has been suggested and could be related to auditory processingproblem. Aim of the work: To assess central auditory processing functions in children having recurrent OME through behavioral and electrophysiological testing, and to correlate between them. Methodology: Sixty children of both genders were enrolled in this study and divided into 30 children with history of recurrent OME and 30 children of age and gender matched control group. All children were subjected to full history taking, basic audiological evaluation, speech intelligibility in noise test (SPIN), click evoked auditory brainstem response (click ABR) and speech evoked auditory brainstem response testing (speech ABR). Results: Comparing both groups revealed statistically significant depressed SPIN scores at different signal to noise ratios in study group even in absence of conductive hearing loss (CHL). Click ABR absolute latencies of wave I, III and V and interpeak latencies I-V and III-V were significantly prolonged due to CHL. Speech ABR showed significant wave V latency shift together with wave A delay, reduced amplitude, prolonged V-A duration and shallower slope even in absence of hearing loss. Conclusion: Children having recurrent OME showed brainstem abnormalities as detected by SPIN, click ABR and speech ABR tests even in absence of hearing loss.Keywords: Otitis media with effusion (OME), conductive hearing loss(CHL), speech auditory brainstem response (speech ABR) and speech intelligibility in noise test (SPIN).