1. The potential role of the cABR in assessment of normal hearing adults with inherited neuropathies.
- Author
-
II Joon Moon, Ji Eun Choi, Yoon Sang Ji, Kyung Myun Lee, Byung-Ok Choi, and Sung Hwa Hong
- Subjects
- *
AUDITORY neuropathy , *AUDITORY evoked response , *BRAIN stem , *CHARCOT-Marie-Tooth disease , *HEARING levels , *NOISE , *SPEECH perception , *ADULTS , *GENETICS - Abstract
Objectives: The aim of this study was to investigate 1) the auditory pathway function and 2) the potential role of the complex auditory brainstem response (cABR) in a group of normal hearing (NH) adults with inherited neuropathies. Material and methods: Thirty-five NH adults with Charcot- Marie-Tooth (CMT) disease and 48 heathy NH listeners participated. We assessed speech in noise perception and recorded ABRs to three speech syllables. We calculated FO amplitude and average phase-shift values. Results: CMT patients showed significantly higher SNR thresholds than control group. Speech in noise perception was significantly correlated with phase difference between /DA/ and /BA/ after controlling age, sex, and pure tone thresholds. Conclusions: While CMT patients had normal pure tone thresholds, they were difficult to understand in noisy background. Speech perception in noise ability was significantly correlated with subcortical auditory processing of speech [ABSTRACT FROM AUTHOR]
- Published
- 2017