1. New-onset systemic lupus erythematosus following BNT162b2 mRNA COVID-19 vaccine: a case series and literature review.
- Author
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Sagy I, Zeller L, Raviv Y, Porges T, Bieber A, and Abu-Shakra M
- Subjects
- BNT162 Vaccine, Humans, Male, RNA, Messenger, Vaccination, Autoimmune Diseases, COVID-19 prevention & control, COVID-19 Vaccines adverse effects, Lupus Erythematosus, Systemic diagnosis
- Abstract
Emerging data evaluated the possible link between the Coronavirus 19 (COVID-19) vaccine and acute flares of rheumatic autoimmune diseases. However, the association between the COVID-19 vaccine and the development of de-novo rheumatic autoimmune diseases remained unclear. We report the first case series of three male patients who developed new-onset systemic lupus erythematosus following receiving Pfizer BNT162b2 mRNA vaccination. The clinical characteristics share some similarities with drug-induced lupus. More patients with SLE following COVID-19 may be diagnosed in the future. Additional studies will provide more significant insights into the possible immunogenic influence of the COVID-19 vaccine., (© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2022
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