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Start Over Author "Rockwitz, K" Topic autoimmune diseases
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1. Comparison of the Clinical Efficacy and Safety of Subcutaneous Versus Oral Administration of Methotrexate in Patients With Active Rheumatoid Arthritis.

Author

Braun, J., Kästner, P., Flaxenberg, P., Währisch, J., Hanke, P., Demary, W., Von Hinüber, U., Rockwitz, K., Heitz, W., Pichlmeier, U., Guimbal-Schmolck, C., and Brandt, A.

Subjects
RHEUMATOID arthritis, METHOTREXATE, DRUG efficacy, IMMUNOSUPPRESSIVE agents, AUTOIMMUNE diseases
Abstract

The article presents a study which compared the efficacy and safety of subcutaneous (SC) versus oral administration of methotrexate (MTX) in patients with active rheumatoid arthritis (RA). The study found that at week 24, significantly more patients treated with SC MTX than with oral MTX showed ACR20 responses. It was also concluded that SC administration was significantly more effective than oral administration of the same MTX dosage.

Published
2008
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