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Background and Aims: Post-exercise recovery strategies include massage, low-intensity active exercise, thermal contrast, hydration, and nutritional and herbal approaches. These strategies aim to accelerate recovery, enhance performance, and optimise the physical training process. L-arginine (L-ARG) is the physiological precursor of nitric oxide (NO), a crucial mediator of vasodilation and the inhibition of platelet aggregation. A previous study reported that L-ARG supplementation could significantly reduce the systolic blood pressure (SBP) and diastolic blood pressure (DBP). This study aimed to investigate the effects of L-ARG on autonomic and cardiovascular recovery immediately following submaximal exercise., Methods and Results: Thirty-two healthy individuals were subjected to two experimental protocols. The first protocol included 60 min of rest, a treadmill warm-up, and load increments until reaching 80% of their maximum HR. Before this protocol, the subjects consumed 3 g of starch (placebo protocol). The second protocol was identical, but the subjects consumed 3 g of L-ARG. Heart rate recovery (HRR), heart rate variability (HRV), and blood pressure (BP) responses were assessed. No significant differences in HRR were found ( p = 0.944) regarding the root mean square of successive differences in the RR interval (RMSSD30) of HRV ( p = 0.562) or in the BP responses (mean arterial pressure (MAP), p = 0.687; pulse pressure (PP), p = 0.929) between the protocols., Conclusions: L-ARG supplementation did not significantly alter immediate post-exercise autonomic recovery in healthy males.

Objective: To evaluate the relationship between birth weight and the autonomic nervous system in adulthood through a systematic review., Data Source: This is a systematic review of publications without limitation of year and language. We included studies involving the autonomic nervous system and birth weight in adults. Manuscripts were selected based on electronic searches of Medical Literature Analysis and Retrieval System Online (MEDLINE), Cumulative Index to Nursing and Allied Health Literature (CINAHL), Web of Science Cochrane Library and Scopus databases, using "Autonomic Nervous System" OR "Heart Rate" OR "Heart Rate Variability" AND "Birth Weight" as a search strategy. This review is registered on the International Prospective Register of Systematic Reviews - PROSPERO (ID: CRD42020165622)., Data Synthesis: We found 894 articles; 215 were excluded for duplicity. Of the remaining 679 studies, 11 remained. Two were excluded because they did not specifically treat the autonomic nervous system or birth weight. There were nine publications, two cohort and seven cross-sectional studies. The main findings were that extreme, very low, low or high birth weight may have some impact on the autonomic nervous system in adult life., Conclusions: Birth weight outside the normality rate may have a negative influence on the autonomic nervous system, causing autonomic dysfunction and increasing the risk of cardiovascular diseases in adult life. Thus, the importance of the follow-up of health professionals from pregnancy to gestation and throughout life, with preventive care being emphasized.

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[Display omitted] • Subjects with CVD may have autonomic modulation impairment. • Postexercise recovery crucial for increased cardiac event risk. • Beetroot and resveratrol supplementation explored for cardioprotection. • Study investigates impact of beet extract and resveratrol on CVD recovery. Postexercise recovery is a crucial period, especially in patients with cardiovascular disease (CVD). Supplementation with nutraceutical substances has been explored due to its potential cardioprotective effects. We aimed to investigate the impact of isolated and combined ingestion of beetroot extract and resveratrol on immediate postexercise recovery. Individuals with CVD were subjected to 4 experimental protocols consisting of 30 min of aerobic exercise. Before exercise, the subjects consumed 500 mg of starch, 500 mg of beetroot extract, 500 mg of resveratrol or both substances. Heart rate recovery (HRR), heart rate variability (HRV) and blood pressure (BP) responses were evaluated. No significant differences in the HRR were detected (p = 0.719) in the RMSSD30 index (p = 0.671) or BP responses (systolic BP − p = 0.703, diastolic BP − p = 0.638) between protocols. Supplementation with beetroot extract and/or resveratrol did not promote significant changes in immediate post-exercise recovery. Registration number - clinicaltrials.gov: NCT06095635 [ABSTRACT FROM AUTHOR]

Aims: Results regarding the effects of caffeine (CAF) intake on the autonomic control of heart rate recovery exercise remain inconclusive. Thus far, no study has used effect measures to pool the results of different experiments. We aim to assess the acute effect of CAF intake before exercise on the recovery of heart rate variability (HRV) after exercise through a systematic review and meta-analysis.Data Synthesis: Randomized controlled clinical trials were included; sample composed of physically active or trained adults; CAF should be offered/ingested before exercise, with dosage between 100 and 400 mg or between 2 and 6 mg/kg and administration/ingestion route analogous in the protocols; studies required to present results of HRV indices before and after exercise. Bias risk analysis and meta-analysis were performed. Twelve studies were included in the qualitative synthesis and five studies were encompassed in the quantitative synthesis (meta-analysis). For the Root-mean-square standard deviation (RMSSD) index we revealed p = 0.67, Total 95% confidence interval (95% CI) ranged from -0.45 to 0.29, and 66.7% for heterogeneity between groups were reported. Concerning the High Frequency (HF) index, we observed p = 0.22, Total 95% CI that ranged from -0.34 to 0.30, and 44% for heterogeneity between groups.Conclusions: CAF intake did not affect heart rate variability recovery after exercise. [ABSTRACT FROM AUTHOR]

Introduction: Energy drink (ED) intake could initiate physiological changes owing to its stimulant characteristics and, it improves endurance and athletic performance. We evaluated the acute effects of ED on autonomic heart rate (HR) control during recovery after a session of submaximal aerobic exercise.Method: The study was completed by submitting 29 healthy males between 18 and 30 years old to three conventions: (A) Maximum exercise test by the adapted Bruce protocol; (B) Placebo protocol (PP) - water intake 15 minutes prior to exercise, rest in dorsal decubitus for 15 minutes followed by 5 minutes of treadmill running at 1% inclination, initial speed of 5 km/h for 5 minutes 25 minutes with 60% of the velocity consistent to the maximum oxygen consumption (VO2max), and finally 60 minutes of recovery at rest in the supine position; (C) Experimental protocol (PE) - similar to PP previously, but with ED intake 15 minutes before physical exercise. The time, frequency and geometric indexes of HR variability (HRV) were inspected before and after exercise.Results: There was a significant (p < 0.05, <5%) effect on the HRV index (HR-nu and ms2, LF-nu and ms2, LF/HF, SD1, SDNN and RMSSD), indicating a reduction in HRV in the first 5 minutes after exercise in both protocols (PP and PE). Yet, no protocol interaction was detected, suggesting no effect of ED on HRV throughout recovery after submaximal aerobic exercise.Conclusion: There was no significant effect of ED on the autonomic control of HR in the recovery phase after submaximal aerobic exercise. [ABSTRACT FROM AUTHOR]