1. Large Deletion of MAGT1 Gene in a Patient with Classic Kaposi Sarcoma, CD4 Lymphopenia, and EBV Infection.
- Author
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Brigida I, Chiriaco M, Di Cesare S, Cittaro D, Di Matteo G, Giannelli S, Lazarevic D, Zoccolillo M, Stupka E, Jenkner A, Francalanci P, Livadiotti S, Morawski A, Ravell J, Lenardo M, Cancrini C, Aiuti A, and Finocchi A
- Subjects
- Calcium Signaling, Child, Child, Preschool, Cytotoxicity, Immunologic, DNA Mutational Analysis, Epstein-Barr Virus Infections genetics, Humans, Immunologic Memory, Lymphocyte Activation, Lymphopenia genetics, Male, Receptors, Antigen, T-Cell metabolism, Sarcoma, Kaposi genetics, B-Lymphocytes immunology, CD4-Positive T-Lymphocytes pathology, Cation Transport Proteins genetics, Epstein-Barr Virus Infections diagnosis, Herpesvirus 4, Human physiology, Lymphopenia diagnosis, Sarcoma, Kaposi diagnosis, Sequence Deletion genetics
- Abstract
Competing Interests: Compliance with Ethical StandardsSource of FundingThe authors would like to thank the European Commission-Advanced Cell-based Therapies for the treatment of Primary Immunodeficiency (HEALTH-F5-2010-261387, CELL-PID to AA and AF), the Italian TELETHON foundation (TIGET Core grant A1), The Italian Ministero della Salute (Programma di rete, NET-2011-02350069), Fondazione Roma and Italian Ministero della Salute (RF-2009-1485896 conv.055), and Ospedale Pediatrico Bambino Gesù Ricerca Corrente (201602PI003708) to CC and AF. IB is supported by the Italian Ministero della Salute (GR-2011-02346985). This work was supported in part by the Intramural Research Programs of the National Institute of Allergy and Infectious Diseases, National Institutes of Health. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Conflict of InterestsThe authors declare that they have no competing interests.
- Published
- 2017
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