1. A Growth Factor for Malo-lactic Fermentation Bacteria
- Author
-
Shoji Imamoto, Hajime Yoshizumi, and Teruo Amachi
- Subjects
biology ,Chemistry ,Stereochemistry ,Growth factor ,medicine.medical_treatment ,Biological activity ,biology.organism_classification ,General Biochemistry, Genetics and Molecular Biology ,carbohydrates (lipids) ,NMR spectra database ,Residue (chemistry) ,medicine ,Malolactic fermentation ,Moiety ,Fermentation ,General Agricultural and Biological Sciences ,Bacteria - Abstract
A growth factor (TJF) for a malo-lactic fermentation bacterium has been isolated from tomato juice, and found to be a β-glucoside. The NMR spectra of TJF and its acetate revealed that the glucosyl residue linked to the hydroxyl group at C-2′ or C-4′ of d- or l-pantothenic acid moiety. Then, 2′-O-(β-d-glucopyranosyl)-dl-pantothenic acid (I), 4′-O-(β-d-glucopyranosyl)-dl-pantothenic acid (II) and 4′-O-(β-d-glucopyranosyl)-d(R)-pantothenic acid (II-a) were synthesized, and Il-a and 4′-O-(β-d-glucopyranosyl)-l-pantothenic acid (II-b) were obtained by the optical resolution of the acetate of II. Among the above compounds, II-a was identical with natural TJF regarding to the biological activity, NMR and ORD spectra, and thin-layer chromatography.
- Published
- 1971