Search

Two-part model (TPM) is a widely appreciated statistical method for analyzing semi-continuous data. Semi-continuous data can be viewed as arising from two distinct stochastic processes: one governs the occurrence or binary part of data and the other determines the intensity or continuous part. In the regression setting with the semi-continuous outcome as functions of covariates, the binary part is commonly modelled via logistic regression and the continuous component via a log-normal model. The conventional TPM, still imposes assumptions such as log-normal distribution of the continuous part, with no unobserved heterogeneity among the response, and no collinearity among covariates, which are quite often unrealistic in practical applications. In this article, we develop a two-part nonlinear latent variable model (TPNLVM) with mixed multiple semi-continuous and continuous variables. The semi-continuous variables are treated as indicators of the latent factor analysis along with other manifest variables. This reduces the dimensionality of the regression model and alleviates the potential multicollinearity problems. Our TPNLVM can accommodate the nonlinear relationships among latent variables extracted from the factor analysis. To downweight the influence of distribution deviations and extreme observations, we develop a Bayesian semiparametric analysis procedure. The conventional parametric assumptions on the related distributions are relaxed and the Dirichlet process (DP) prior is used to improve model fitting. By taking advantage of the discreteness of DP, our method is effective in capturing the heterogeneity underlying population. Within the Bayesian paradigm, posterior inferences including parameters estimates and model assessment are carried out through Markov Chains Monte Carlo (MCMC) sampling method. To facilitate posterior sampling, we adapt the Polya-Gamma stochastic representation for the logistic model. Using simulation studies, we examine properties and merits of our proposed methods and illustrate our approach by evaluating the effect of treatment on cocaine use and examining whether the treatment effect is moderated by psychiatric problems. [ABSTRACT FROM AUTHOR]

Factor analysis models with continuous and ordinal responses are a useful tool for assessing relations between the latent variables and mixed observed responses. These models have been successfully applied to many different fields, including behavioral, educational, and social-psychological sciences. However, within the Bayesian analysis framework, most developments are constrained within parametric families, of which the particular distributions are specified for the parameters of interest. This leads to difficulty in dealing with outliers and/or distribution deviations. In this paper, we propose a Bayesian semiparametric modeling for factor analysis model with continuous and ordinal variables. A truncated stick-breaking prior is used to model the distributions of the intercept and/or covariance structural parameters. Bayesian posterior analysis is carried out through the simulation-based method. Blocked Gibbs sampler is implemented to draw observations from the complicated posterior. For model selection, the logarithm of pseudomarginal likelihood is developed to compare the competing models. Empirical results are presented to illustrate the application of the methodology. [ABSTRACT FROM AUTHOR]