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Your search keyword '"Scherstén T"' showing total 16 results
Start Over Author "Scherstén T" Topic bile acids and salts
16 results on '"Scherstén T"'

1. Supersaturated bile--is it due to a metabolic disorder or to an impaired gallbladder?

Author

Scherstén T, Cahlin E, Jönsson J, Lindblad L, and Nilsson S

Subjects
Adult, Catheterization, Cholecystectomy, Cholelithiasis surgery, Cholesterol metabolism, Chromatography, Thin Layer, Circadian Rhythm, Female, Humans, Male, Middle Aged, Phosphatidylcholines metabolism, Phospholipids metabolism, Secretory Rate, Time Factors, Bile metabolism, Bile Acids and Salts metabolism, Cholelithiasis metabolism, Gallbladder metabolism
Published
1974

2. Bile flow and biliary lipid secretion following release of biliary obstruction in man.

Author

Lindblad L, Hammarsten J, and Scherstén T

Subjects
Aged, Cholestasis surgery, Common Bile Duct surgery, Female, Humans, Male, Middle Aged, Secretory Rate, Bile metabolism, Bile Acids and Salts metabolism, Cholestasis metabolism, Cholesterol metabolism, Phosphatidylcholines metabolism
Abstract

In order to elucidate the relationship between bile acid secretion and the secretion of lecithin and cholesterol in the postcholestatic condition, five patients were studied after release of complete biliary obstruction. Ten patients operated on for uncomplicated gallstone disease served as controls. The secretion of bile acids, which constituted only newly synthesized acids, increased in the postcholestatic period 2.5-22 times. In spite of that the secretion rate of bile acids was low (less than or equal to 7.5 mumol x min-1). The pattern of the relationships between bile acid secretion and bile flow and bile acid secretion and lecithin and cholesterol secretion was the same in the postcholestatic patients as in the controls. However, the bile flow showed a higher bile acid dependency in the postcholestatic condition, and the bile-acid-independent flow varied considerably in these patients as compared with controls. Linear relations between the secretion rate of bile acids and lecithin and cholesterol secretion rates were found. Extrapolation to zero bile secretion revealed Y-intercepts, which were not statistically significantly different from origo. Calculations of bile acid - lecithin and bile acid - cholesterol relations in the controls at correspondingly low bile acid secretion rates (less than or equal to 5 mumol x min-1) gave results similar to those in the study group. The bile was supersaturated with cholesterol in all the postcholestatic patients similar to the condition in the controls at correspondingly low bile acid secretion rates. It is concluded that the bile acids are determinative for the biliary secretion of cholesterol and lecithin even at very low bile acid secretion rates. This conclusion was valid in patients with presumably normal liver function as well as in the early phase after release of severe cholestasis.

Published
1975

3. Bile acid conjugation in human liver homogenates obtained from percutaneous biopsies.

Author

Scherstén T, Gottfries A, and Ekdahl PH

Subjects
Adult, Bile Acids and Salts analysis, Cholecystitis metabolism, Cholecystitis surgery, Cholelithiasis metabolism, Cholelithiasis surgery, Cholestasis metabolism, Cholestasis surgery, Female, Humans, Liver analysis, Male, Methods, Middle Aged, Bile Acids and Salts biosynthesis, Biopsy, Liver metabolism
Published
1968

4. Synthesis of phospholipids and triglycerides in human liver slices. 3. Influence of bile acids, choline, and linoleic acid.

Author

Cahlin E, Jönsson J, Nilsson S, and Scherstén T

Subjects
Carbon Isotopes, Chromatography, Thin Layer, Female, Glycerol metabolism, Glycerol pharmacology, Glycerophosphates biosynthesis, Glycerophosphates metabolism, Humans, In Vitro Techniques, Male, Middle Aged, Palmitic Acids pharmacology, Bile Acids and Salts pharmacology, Choline pharmacology, Linoleic Acids pharmacology, Liver metabolism, Phosphatidylcholines biosynthesis, Triglycerides biosynthesis
Published
1972
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5. Biliary lipid composition in normalipidemic and prebeta hyperlipoproteinemic gallstone patients. Influence of sucrose feeding of the patients on the biliary lipid composition.

Author

Cahlin E, Jönsson J, Nilsson S, and Scherstén T

Subjects
Chenodeoxycholic Acid analysis, Cholesterol analysis, Dietary Carbohydrates, Female, Humans, Hyperlipidemias metabolism, Lipoproteins, VLDL, Liver metabolism, Male, Middle Aged, Phosphatidylcholines analysis, Stimulation, Chemical, Sucrose pharmacology, Bile analysis, Bile Acids and Salts analysis, Cholelithiasis metabolism, Lipids analysis
Published
1973

8. Relationship between the biliary excretion of bile acids and the excretion of water, lecithin, and cholesterol in man.

Author

Scherstén T, Nilsson S, Cahlin E, Filipson M, and Brodin-Persson G

Subjects
Adult, Bile Acids and Salts physiology, Cholelithiasis surgery, Duodenum surgery, Female, Humans, Intubation, Gastrointestinal, Liver metabolism, Male, Middle Aged, Phosphatidylcholines biosynthesis, Portal System surgery, Secretory Rate, Bile metabolism, Bile Acids and Salts metabolism, Cholesterol metabolism, Phosphatidylcholines metabolism, Water metabolism
Published
1971
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9. The synthesis of taurocholic and glycocholic acids by preparations of human liver. II. An analysis of the stimulating effect of the L fraction.

Author

Scherstén T, Björntorp P, Ekdahl PH, and Björkerud S

Subjects
Acid Phosphatase metabolism, Biopsy, Centrifugation, Density Gradient, Coenzyme A, Freezing, Glucose-6-Phosphatase metabolism, Humans, Lysosomes metabolism, Microsomes metabolism, Stimulation, Chemical, Bile Acids and Salts biosynthesis, Hydroxamic Acids biosynthesis, Liver metabolism, Lysosomes enzymology, Microsomes enzymology
Published
1967
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11. Importance of bile acids for phospholipid secretion into human hepatic bile.

Author

Nilsson S and Scherstén T

Subjects
Adult, Aged, Bile Acids and Salts biosynthesis, Cholesterol metabolism, Common Bile Duct, Female, Humans, Liver metabolism, Liver Circulation, Male, Middle Aged, Phospholipids biosynthesis, Bile analysis, Bile Acids and Salts physiology, Phospholipids metabolism
Published
1969

13. The synthesis of cholic acid conjugates in human liver. An analysis of factors controlling the subcellular synthesis of bile acid conjugates in normal and cholestatic conditions.

Author

Scherstén T

Subjects
Acid Phosphatase metabolism, Acyltransferases metabolism, Adenosine Triphosphatases metabolism, Bilirubin pharmacology, Binding Sites, Biopsy, Carbon Isotopes, Centrifugation, Density Gradient, Chromatography, Thin Layer, Dinitrophenols pharmacology, Fatty Acids pharmacology, Humans, In Vitro Techniques, Liver enzymology, Oligomycins pharmacology, Oxygen metabolism, Bile Acids and Salts biosynthesis, Cholestasis metabolism, Liver cytology, Lysosomes metabolism, Microsomes metabolism, Mitochondria, Liver metabolism, Taurine biosynthesis
Published
1967

15. The synthesis of taurocholic and glycocholic acids by preparations of human liver. I. Distribution of activity between subcellular fractions.

Author

Scherstén T

Subjects
Adenosine Triphosphate metabolism, Carbon Isotopes, Centrifugation, Chromatography, Thin Layer, Humans, Liver Function Tests, Lysosomes enzymology, Microsomes enzymology, Mitochondria, Liver metabolism, Proteins metabolism, Bile Acids and Salts biosynthesis, Hydroxamic Acids biosynthesis, Liver metabolism, Lysosomes metabolism, Microsomes metabolism
Published
1967

16. Formation of lithogenic bile in man

Author

Scherstén T

Subjects
Male, medicine.medical_specialty, Blood Protein Disorders, medicine.medical_treatment, Hyperlipidemias, Lipoproteins, VLDL, Gastroenterology, Bile Acids and Salts, chemistry.chemical_compound, Text mining, Cholelithiasis, Pregnancy, Chenodeoxycholic acid, Internal medicine, medicine, Animals, Bile, Humans, Phospholipids, Cholesterol, business.industry, General surgery, Gallbladder, Gallstones, Vagotomy, medicine.disease, Pregnancy Complications, medicine.anatomical_structure, chemistry, Liver, Phosphatidylcholines, Gastrectomy, Female, Bile Ducts, business, Cholecystokinin, Liver Circulation
Published
1973

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