1. Triterpenes from Astilbe chinensis.
- Author
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Hu, Jun-Yi, Yao, Zhi, Xu, Ying-Qian, Takaishi, Yoshihisa, and Duan, Hong-Quan
- Subjects
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ASTILBE , *PHYTOTHERAPY , *CHINESE medicine , *BIOACTIVE compounds , *HERBAL medicine , *SPECTRUM analysis - Abstract
Six new triterpenes, 3β,6β-dihydroxyurs-12-en-27-oic acid (1), 3β,6β,24-trihydroxyurs-12-en-27-oic acid (2), 3β,6β,7α-trihydroxyurs-12-en-27-oic acid (3), 3β-acetoxy-6β-hydroxyurs-12-en-27-oic acid (4), 3β,6β,24-trihydroxyolean-12-en-27-oic acid (5), and 3β,6β,7α-trihydroxyolean-12-en-27-oic acid (6), were isolated from the rhizomes of Astilbe chinensis. Their structures were elucidated on the basis of 1D- and 2D-NMR analyses and HR-MS experiments. The isolated compounds exhibited significant cytotoxic activities against the SK-N-SH and HL-60 cell lines. [ABSTRACT FROM AUTHOR]
- Published
- 2009
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