1. Influence of process conditions on hydroxyapatite crystallinity obtained by direct crystallization
- Author
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Marcelo Martins Seckler, Marco Giulietti, José Vicente Valarelli, R. Rodríguez-Clemente, Silas Derenzo, and M. Danese
- Subjects
Materials science ,Biomaterial crystallization recipitation ,Mineralogy ,Bioceramic ,law.invention ,chemistry.chemical_compound ,Crystallinity ,law ,lcsh:TA401-492 ,General Materials Science ,Crystallization ,Supersaturation ,biomaterial crystallization precipitation ,Mechanical Engineering ,Bioceramics ,Biomaterial ,hydroxyapatite ,Condensed Matter Physics ,Chemical engineering ,chemistry ,Mechanics of Materials ,bioceramic ,Carbonate ,lcsh:Materials of engineering and construction. Mechanics of materials ,Particle size ,Stoichiometry - Abstract
Crystallization from solutions was applied to produce stoichiometric and crystalline hydroxyapatite (HAP) suitable for use as a biomaterial. This was accomplished by keeping a low supersaturation through the following procedure: semi-continuous operating mode, slow reactant addition rate and addition of a calcium complexing agent. A high temperature (90 °C) and probably carbonate incorporation also favored the formation of a well crystallized material. A qualitative correlation was found between the supersaturation and HAP properties such as crystallinity and particle size, Near-stoichiometric and well crystallized hydroxyapatite was obtained by means of a semi-continuous procedure. Changes in crystallinity and particle size due to varying reagent addition rate, base concentration and pH were consistent with the corresponding changes in the su- Financiadora de Estudos e Projetos do Ministério de Ciência e Tecnologia, Brazil - and CYTED - Programa Iberoamericano de Ciencia y Tecnologia para el Desarollo, proj. VIII.6, Spain - for the financial support.
- Published
- 1999