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[Display omitted] • Composition of dairy, swine and poultry farm wastewater is discussed. • Annamox and genetically modified bacteria-based treatment strategies are covered. • Microalgal, oxidation and membrane-based wastewater treatment are also discussed. • Bioplastic, biofertilizer and biofuel can be produced from farm wastewater. • Microalgal-microbial fuel cells can be developed using livestock wastewater. Livestock and poultry wastewater poses a potent risk for environmental pollution accelerating disease load and premature deaths. It is characterized by high chemical oxygen demand, biological oxygen demand, suspended solids, heavy metals, pathogens, and antibiotics, among other contaminants. These contaminants have a negative impact on the quality of soil, groundwater, and air, and is a potential hazard to human health. Depending on the specific characteristics of wastewater, such as the type and concentration of pollutants present; several physical, chemical and biological strategies have been developed for its treatment. This review aims at providing comprehensive overview of the profiling of livestock wastewater from the dairy, swine and poultry sub-sectors along with the biological, physico-chemical, AI-based and integrated treatment methodologies, and valorisation for the generation of value-added products such as bioplastics, biofertilizers, biohydrogen and microalgal-microbial fuel cells. Additionally, future perspectives for efficient and sustainable wastewater treatment are contemplated. [ABSTRACT FROM AUTHOR]