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Your search keyword '"Aravinda Babu"' showing total 3 results
Start Over Author "Aravinda Babu" Topic biochemistry
3 results on '"Aravinda Babu"'

1. Effect of chrysotile asbestos (AP-I) on sister chromatid exchanges in Chinese hamster ovary cells

Author

K. Aravinda Babu, Bhatt Dk, Thakore Kn, Nigam Sk, S. K. Kashyap, Karnik Ab, Lakkad Bc, and Chatterjee Sk

Subjects
Linear relationship, Chemistry, Chinese hamster ovary cell, Asbestos fibers, Chrysotile, medicine, Sister chromatids, medicine.disease_cause, Biochemistry, Molecular biology, Asbestos, General Environmental Science
Abstract

In vitro effect of an Indian variety of chrysotile asbestos from Andhra Pradesh (AP-I) is evaluated using sister chromatid exchanges (SCEs) in Chinese hamster ovary (CHO) cells. Cultures were treated for 24 hr with different concentrations of asbestos fibers, i.e., 0.1, 1, 10, and 100 μg/ml of medium. Sister chromatid exchanges were elevated even with the lowest concentration used. However, the linear relationship between SCEs and asbestos concentration is not seen.

Published
1981

2. Recovery of benthiocarb-inhibited AChE in fish brain: an in vitro study

Author

G. Ramesh Reddy, P.R. Aravinda Babu, C.S. Chetty, and G.R. Veera Babu

Subjects
Aché, Health, Toxicology and Mutagenesis, Biology, Pharmacology, In Vitro Techniques, chemistry.chemical_compound, In vivo, Thiocarbamates, Animals, Water Pollutants, IC50, Benthiocarb, Public Health, Environmental and Occupational Health, Fishes, Brain, General Medicine, Pollution, Acetylcholinesterase, In vitro, language.human_language, chemistry, Biochemistry, Toxicity, language, Specific activity, Cholinesterase Inhibitors, Water Pollutants, Chemical
Abstract

The effects in vivo and in vitro of benthiocarb, an organocarbamate, on acetylcholinesterase (AChE) activity and its recovery in vitro in the brain of the freshwater fish Sarotherodon mossambicus have been studied. Findings revealed that the specific activity of AChE was inhibited both in vivo and in vitro in a concentration-dependent manner. Of the different modulators tested, dexamethasone (0.72 mg), prednisolone (0.74 mg), testosterone (0.9 mg), and ADP (9.5 mg) were found to neutralize the inhibitory effect (IC50 = 0.30 μM) of benthiocarb on AChE.

Published
1989

3. Early changes in serum protein and liver LDH isoenzymes in mice exposed to technical grade hexachlorocyclohexane (BHC) and their possible relationship to liver tumours

Author

Bhatt Dk, S. K. Kashyap, Lakkad Bc, Nigam Sk, Chatterjee Sk, K. Aravinda Babu, Thakore Kn, and Karnik Ab

Subjects
medicine.medical_specialty, Time Factors, Serum protein, Hexachlorocyclohexane, Biology, Toxicology, Isozyme, chemistry.chemical_compound, Mice, Internal medicine, medicine, Animals, Protein pattern, L-Lactate Dehydrogenase, Liver Neoplasms, Liver tumours, Blood Proteins, Neoplasms, Experimental, Ldh isoenzymes, Blood proteins, Isoenzymes, Endocrinology, chemistry, Biochemistry, Liver, Technical grade
Abstract

Mice were exposed to hexachlorocyclohexane (BHC) in order to study the changes in the serum protein pattern and in the LDH isoenzymes of the liver. After 2 months of exposure the protein pattern showed a new band which persisted even after the development of a tumour. The LDH isoenzymes pattern showed a gradual decrease of the faster moving LDH-1 and LDH-2 bands which later disappeared completely when hepatic tumours formed. The significance of these results is discussed.

Published
1981

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