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Start Over Author "HENDRA, PJ" Topic biocompatible materials

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1. The application of Fourier-transform Raman spectroscopy to the analysis of pharmaceuticals and biomaterials.

Author

Tudor AM, Melia CD, Binns JS, Hendra PJ, Church S, and Davies MC

Subjects
Anhydrides analysis, Ephedrine analysis, Excipients, Fourier Analysis, Norepinephrine analysis, Phenylephrine analysis, Polymers, Spectrum Analysis, Raman, Sympathomimetics analysis, Biocompatible Materials analysis, Pharmaceutical Preparations analysis
Abstract

Near infrared Fourier-transform (FT) Raman spectroscopy is shown to be a useful spectroscopic tool for the molecular structural analysis of drugs and biomedical polymers. The technique has been applied to the non-invasive investigation of the hydrolytic degradation of a biodegradable polymer in water over a period of 15 days and to the analysis of a drug within a polymer vehicle over a wide drug concentration range. This work demonstrates the potential value of FT Raman spectroscopy in the field of pharmaceutical science.

Published
1990
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