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The manipulation of cytostatic drugs used in the treatment of cancer is a matter of knowing and following strict rules of transport, dilution and administration. Also, accidents that may occur through leakage of cytostatic solutions (contamination) must be prevented and decontamination maneuvers must be known. Disposal of waste resulting from the administration of chemotherapy, as well as biological products from the patients treated with cytostatics should also be known by those who manipulate the cytostatics. Another point of interest in the manipulation of the cytostatics is the use of the hood, the working mode with the hood and the rules imposed in the room where the hood is located. In this article, in addition to the above, I present some aspects related to the decontamination of medical personnel in case of accidental contamination and the procedure in case of extravasation of the cytostatics. [ABSTRACT FROM AUTHOR] more...