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Restraint and threat of predation are possibly the most stressful events in wild animals' lives. Management techniques should, therefore, be improved to avoid or minimize suffering in such situations. Body mass and variation in behavior influence the techniques used during containment. Automatic traps are mostly used for small primates living in the lower canopy, while remotely delivered chemical immobilization is the recommended technique for larger primates, which live in the upper canopy. For both methods, careful physical restraint after the capture of the animal is essential. The use of equipment and materials that ensure biosecurity is imperative, as is choosing the most appropriate location for the collection of biological samples. Storage and transport must also be carried out in an adequate manner so as not to impair the samples. Here, therefore, we seek to describe capture, containment, and biological sample collection techniques with the intention of minimizing risks and increase success in the capture of Neotropical primates. [ABSTRACT FROM AUTHOR]