1. Coloured Petri nets for multi-level, multiscale, and multi-dimensional modelling of biological systems
- Author
-
David Gilbert, Monika Heiner, and Fei Liu
- Subjects
0301 basic medicine ,Paper ,Theoretical computer science ,Scale (ratio) ,Computer science ,coloured Petri nets ,biological systems ,Color ,02 engineering and technology ,Single level ,Models, Biological ,03 medical and health sciences ,multilevel ,0202 electrical engineering, electronic engineering, information engineering ,Humans ,Computer Simulation ,multiscale and multidimensional ,Molecular Biology ,multiscale and multidimensional modelling ,Biological phenomenon ,Modelling biological systems ,Systems Biology ,Petri net ,multi-level ,030104 developmental biology ,020201 artificial intelligence & image processing ,Information Systems - Abstract
Due to the availability of data of one biological phenomenon at different levels/scales, modelling of biological systems is moving from single level/scale to multiple levels/scales, which introduces a number of challenges. Coloured Petri nets have been successfully applied to multi-level, multiscale and multi-dimensional modelling of some biological systems, addressing many of these challenges. In this paper, we first review the basics of coloured Petri nets and some popular extensions, and then their applications for multi-level, multiscale and multi-dimensional modelling of biological systems. This understanding how to use coloured Petri nets for modelling biological systems will assist readers in selecting appropriate coloured Petri net classes for specific modelling circumstances.
- Published
- 2017