1. Sarcoma mieloide: Caso clínico con trisomia 11
- Author
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Anya Lincopán S, Ximena Barraza O, Yenny Valencia M, and Cristian Carrasco L
- Subjects
Pathology ,medicine.medical_specialty ,medicine.diagnostic_test ,FISH antifreeze proteins ,Chromosome ,Chromosomal translocation ,Chromosome 11 trisomy ,General Medicine ,In situ hybridization ,Biology ,medicine.disease ,Sarcoma, myeloid ,medicine.anatomical_structure ,Bone marrow aspirate ,Biopsy ,medicine ,Myeloid sarcoma ,Bone marrow ,Trisomy - Abstract
Myeloid sarcoma is a form of extra-medullary myeloid neoplasia. Cytogenetic characterization is hampered in the absence of invasion to the bone marrow, origin of cells that are usually studied in cytogenetic studies. We report a 13 years old mole presenting with a mass in the right shoulder. A biopsy of the tumor disclosed a Myeloid Sarcoma. A conventional cytogenetic study of a bone marrow aspirate did not show t (8;21) translocation. A fluorescent in situ hybridization (FISH) performed in the paraffin embedded biopsy of the tumor, detected a chromosome 11 trisomy. more...
- Published
- 2011
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