1. The MYB–bHLH–WDR interferers (MBWi) epigenetically suppress the MBW's targets
- Author
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Cuong Thach Nguyen, Gia-Buu Tran, and Nguyen Hoai Nguyen
- Subjects
Transcriptional Activation ,0303 health sciences ,Plant growth ,Arabidopsis Proteins ,Arabidopsis ,Repressor ,Cell Biology ,General Medicine ,Root hair ,Biology ,biology.organism_classification ,Cell biology ,03 medical and health sciences ,Phenotype ,0302 clinical medicine ,Transcription (biology) ,Basic Helix-Loop-Helix Transcription Factors ,MYB ,Gene Silencing ,Signalling pathways ,Transcription factor ,030217 neurology & neurosurgery ,Transcription Factors ,030304 developmental biology - Abstract
Active repressors have been evidenced to function in different plant growth and development programs including hormonal signalling pathways. In Arabidopsis, the MYB-bHLH-WDR (MBW) complex is known to regulate different phenotypic traits such as anthocyanin biosynthesis, seed coat colour, trichome and root hair patterning. A number of transcription factors have been identified to play a negative role in the regulation of these traits via the interruption of MBW formation and function. Since these transcription factors work to interfere with the MBW complex, this review suggests their general name as MBW interferers (MBWi). Recent studies have shed light on the molecular mechanism of these MBWi and this review is aiming to provide a precise view of these MBWi. Moreover, from these, a new characteristic of active repressors is also updated.
- Published
- 2019