1. Postprandial Metabolic Response to Rapeseed Protein in Healthy Subjects
- Author
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Osama Gargum, Frank Hirche, Ulf Schlegelmilch, Corinna Brandsch, Hendrik Treede, Tanja Schwerdtle, Johannes F. Kopp, Monika Wensch-Dorendorf, Claudia Wiacek, Peggy G. Braun, Andreas Simm, Christin Volk, and Gabriele I. Stangl
- Subjects
0301 basic medicine ,Adult ,Blood Glucose ,Male ,Rapeseed ,Adolescent ,medicine.medical_treatment ,030209 endocrinology & metabolism ,postprandial study ,lcsh:TX341-641 ,soy protein ,Biology ,Satiation ,metabolic response ,Plant Proteins, Dietary ,Article ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Double-Blind Method ,medicine ,Humans ,Insulin ,Urea ,Food science ,Amino Acids ,Soy protein ,rapeseed protein ,030109 nutrition & dietetics ,Nutrition and Dietetics ,Cross-Over Studies ,Brassica napus ,Biological value ,Metabolism ,Middle Aged ,Postprandial Period ,Lipids ,Healthy Volunteers ,Human nutrition ,Postprandial ,Plant protein ,healthy subjects ,Soybean Proteins ,Female ,lcsh:Nutrition. Foods and food supply ,Food Science - Abstract
Plant proteins have become increasingly important for ecological reasons. Rapeseed is a novel source of plant proteins with high biological value, but its metabolic impact in humans is largely unknown. A randomized, controlled intervention study including 20 healthy subjects was conducted in a crossover design. All participants received a test meal without additional protein or with 28 g of rapeseed protein isolate or soy protein isolate (control). Venous blood samples were collected over a 360-min period to analyze metabolites, satiety was assessed using a visual analog scale. Postprandial levels of lipids, urea, and amino acids increased following the intake of both protein isolates. The postprandial insulin response was lower after consumption of the rapeseed protein than after intake of the soy protein (p <, 0.05), whereas the postmeal responses of glucose, lipids, interleukin-6, minerals, and urea were comparable between the two protein isolates. Interestingly, the rapeseed protein exerted stronger effects on postprandial satiety than the soy protein (p <, 0.05). The postmeal metabolism following rapeseed protein intake is comparable with that of soy protein. The favorable effect of rapeseed protein on postprandial insulin and satiety makes it a valuable plant protein for human nutrition.
- Published
- 2020