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ABSTRACT Covalently crosslinked polyurethane/urea polymers were synthesized using diamine monomers modified with pendant glucose groups and 2,4-toluene diisocyanate, poly(ethylene glycol) (PEG), and 1,1,1-tris(hydroxymethyl)ethane (triol) comonomers. The polymers showed shape memory behavior with a switching temperature dependent on the glass transition temperature. The glass transition temperature is tuned by varying the mole ratio between the glucose-diamine and PEG used in the polymerization. Increasing PEG content resulted in decreasing glass transition temperature, and a glass transition temperature of 39 °C, close to physiological temperatures, was obtained. The fixed shape showed gradual shape recovery behavior, but a fixity of 70% was achieved when the material was stored at 25 °C. The polymer recovered to the permanent shape when heated to 50 °C. Finally, the surface of a film of the polymer can be sulfated to achieve increased blood-compatibility without sacrificing the shape memory properties. © 2015 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2015, 53, 2252-2257 [ABSTRACT FROM AUTHOR]

ABSTRACT N-alkyl urea peptoid oligomers containing glucose or mannose have been synthesized and characterized. The oligomers were subsequently polymerized using a step-growth polymerization with hexamethylene diisocyanate. Equal moles of both monomers were used to guarantee high-molecular weight polymers. The polymers were characterized by gel permeation chromatography, nuclear magnetic resonance, and Fourier-transform infrared spectroscopy, and contact angle measurements of solvent cast thin films. Sulfation of the final polymers was achieved using a SO3/pyridine complex in pyridine to afford the heparin biomimetics. The average degree of sulfation was calculated to be 3.5 sulfates per saccharide as measured by elemental analysis. © 2013 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2013, 51, 5230-5238 [ABSTRACT FROM AUTHOR]