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Biomechanics as a discipline is ideally placed to increase awareness and participation of girls and women in science, technology, engineering, and mathematics. A nationwide Biomechanics and Research Innovation Challenge (BRInC) centered on mentoring and role modeling was developed to engage high school girls (mentees) and early-mid-career women (mentors) in the field of biomechanics through the completion of a 100-day research and/or innovation project. This manuscript describes the development, implementation, and uptake of the inaugural BRInC program and synthesizes the research and innovation projects undertaken, providing a framework for adoption of this program within the global biomechanics community. Eighty-seven high school girls in years 9 and 10 (age range: 14–16 y) were mentored in teams (n = 17) by women in biomechanics (n = 24). Using a design thinking approach, teams generated solutions to biomechanics-based problem(s)/research question(s). Eight key reflections on program strengths, as well as areas for improvement and planned changes for future iterations of the BRInC program, are outlined. These key reflections highlight the innovation, impact, and scalability of the program; the importance of a program framework and effective communication tools; and implementation of strategies to sustain the program as well as the importance of diversity and building a sense of community. [ABSTRACT FROM AUTHOR]

OpenCap is a web-based markerless motion capture platform that estimates 3D kinematics from videos recorded from at least two iOS devices. This study aimed to determine the concurrent validity and inter-session reliability of OpenCap for measuring trunk and lower-limb kinematics during squatting, hopping, countermovement jumping, and cutting. Nineteen participants (10 males, 9 females; age 27.7 ± 4.1 years) were included. Countermovement jump, single-leg triple vertical hop, single-leg squat, sidestep cutting and side hop tasks were assessed. For validity, OpenCap was compared to a marker-based motion capture system using root-mean-square error. Test–retest reliability of OpenCap was determined using intraclass correlations and minimum detectable change (MDC) from two testing sessions. The squat had the lowest RMSE across joint angles (mean = 7.0°, range = 2.9° to 13.6°). For peak angles, the countermovement jump (jump phase) (ICC = 0.62–0.93) and the squat (ICC = 0.60–0.92) had the best reliability across all joints. For initial contact, the side hop had the best inter-session reliability (ICC = 0.70–0.94) across all joint angles. As such, OpenCap validity and reliability are joint and task specific. [ABSTRACT FROM AUTHOR]

Altered semitendinosus (ST) morphology and distal tendon insertion following anterior cruciate ligament reconstruction (ACLR) may reduce knee flexion torque generating capacity of the hamstrings via impaired ST force generation and/or moment arm. This study used a computational musculoskeletal model to simulate mechanical consequences of tendon harvest for ACLR on ST function by modeling changes in ST muscle tendon insertion point, moment arm, and torque generating capacity across a physiological range of motion. Simulated ST function was then compared between ACLR and uninjured contralateral limbs. Magnetic resonance imaging from 18 individuals with unilateral history of ACLR involving a hamstring autograft was used to analyse bilateral hamstring muscle (ST, semimembranosus, bicep femoris long head and short head) morphology and distal ST tendon insertion. The ACLR cohort was sub‐grouped into those with and without ST regeneration. For each participant with ST regeneration (n = 7), a personalized musculoskeletal model was created including postoperative remodeling of ST using OpenSim 4.1. Knee flexion and internal rotation moment arms and torque generating capacities of hamstrings were evaluated. Bilateral differences were calculated with an asymmetry index (%) ([unaffected limb–affected limb]/[unaffected limb + affected limb]*100%). Smaller moment arms or knee torques within injured compared to uninjured contralateral limbs were considered a deficit. Compared to uninjured contralateral limbs, ACLR limbs with tendon regeneration (n = 7) had minor reductions in knee flexion (5.80% [95% confidence interval (CI) = 3.97–7.62]) and internal rotation (4.92% [95% CI = 2.77–7.07]) moment arms. Decoupled from muscle morphology, altered ST moment arms in ACLR limbs with tendon regeneration resulted in negligible deficits in knee flexion (1.20% [95% CI = 0.34–2.06]) and internal rotation (0.24% [95% CI = 0.22–0.26]) torque generating capacity compared to uninjured contralateral limbs. Coupled with muscle morphology, ACLR limbs with tendon regeneration had substantial deficits in knee flexion (19.32% [95% CI = 18.35–20.28]) and internal rotation (15.49% [95% CI = 14.56–16.41]) torques compared to uninjured contralateral limbs. Personalized musculoskeletal models with measures of ST distal insertion and muscle morphology provided unique insights into post‐ACLR ST and hamstring function. Deficits in knee flexor and internal rotation moment arms and torque generating capacities were evident in those with ACLR even when tendon regeneration occurred. Future studies may wish to implement this framework in personalized musculoskeletal models following ACLR to better understand individual muscle function for injury prevention and treatment evaluation. [ABSTRACT FROM AUTHOR]

Background: One mechanism by which exercise interventions may be effective in reducing anterior cruciate ligament (ACL) injury risk is through changes in lower limb biomechanics. Understanding how training programmes affect lower-limb kinematics and kinetics may help refine injury prevention programmes. Objective: The aim of this systematic review and meta-analysis was to assess the effect of injury prevention programmes on kinematics and kinetics during tasks related to ACL injury in female team field and court sports. Data Sources: Five databases were searched in October 2022. Eligibility Criteria: Randomised controlled trials assessing the effect of injury prevention programmes compared with usual training/no training on lower limb kinematics and kinetics in female team field and court sports were eligible for review. Results: Sixteen studies were included. A total of 976 female athletes were included. Most of the studies included interventions with multiple components (12/16). Commonly used components were plyometrics (12/16), strength (8/16), and balance/stability (7/16). Thirteen studies had routine training or sham interventions as the control group and three studies had no training. Very low certainty evidence suggests that injury prevention programmes increase knee flexion angles (mean difference = 3.1° [95% confidence interval 0.8–5.5]); however, very low to low certainty evidence suggests no effect on hip flexion angles/moments, knee flexion moments, hip adduction angles/moments, knee adduction angles/moments, hip internal rotation angles/moments, ankle dorsiflexion angles, and ground reaction forces, compared with usual training/no training. Conclusion: Injury prevention programmes may be effective in increasing knee flexion angles during dynamic landing and cutting tasks but may have no effect on other lower limb biomechanical variables. As such, the benefits of injury prevention programmes may be mediated by factors other than altered biomechanics and/or may happen through other biomechanical measures not included in this review. [ABSTRACT FROM AUTHOR]

Biomechanics plays a significant yet complex role in osteoarthritis (OA) onset and progression. Identifying alterations in biomechanical factors and their complex interactions is critical for gaining new insights into OA pathophysiology and identification of clearly defined and modifiable mechanical treatment targets. This review synthesized biomechanics studies from March 2022 to April 2023, from which three themes relating to human gait emerged: (1) new insights into the pathogenesis of OA using computational modeling and machine learning, (2) technology-enhanced biomechanical interventions for OA, and (3) out-of-lab biomechanical assessments of OA. We further highlighted future-focused areas which may continue to advance the field of biomechanics in OA, with a particular emphasis on exploiting technology to understand and treat biomechanical mechanisms of OA outside the laboratory. The breadth of studies included in this review highlights the complex role of biomechanics in OA and showcase numerous innovative and outstanding contributions to the field. Exciting cross-disciplinary efforts integrating computational modeling, mobile sensors, and machine learning methods show great promise for streamlining in vivo multi-scale biomechanics workflows and are expected to underpin future breakthroughs in the understanding and treatment of biomechanics in OA. [ABSTRACT FROM AUTHOR]

People with mild-to-moderate hip osteoarthritis (OA) exhibit hip muscle weakness, alterations in hip kinematics and kinetics and hip contact forces during gait compared to healthy controls. However, it is unclear if those with hip OA use different motor control strategies to coordinate the motion of the centre of mass (COM) during gait. Such information could provide further critical assessment of conservative management strategies implemented for people with hip OA. Do muscle contributions to the acceleration of the COM during walking differ between individuals with mild-to-moderate hip OA and controls? Eleven individuals with mild-to-moderate hip OA and 10 healthy controls walked at a self-selected speed while whole-body motion and ground reaction forces were measured. Muscle forces during gait were obtained using static optimisation and an induced acceleration analysis was performed to determine individual muscle contributions to the acceleration of the COM during single-leg stance (SLS). Between-group comparisons were made using independent t-tests via Statistical Parametric Modelling. There were no between-group differences in spatial-temporal gait parameters or three-dimensional whole-body COM acceleration. The rectus femoris, biceps femoris, iliopsoas and gastrocnemius muscles in the hip OA group contributed less to the fore-aft accelerations of the COM (p < 0.05), and more to the vertical COM acceleration with the gluteus maximus (p < 0.05), during SLS, compared to the control group. Subtle differences exist in the way people with mild-to-moderate hip OA use their muscles to accelerate the whole-body centre of mass during the SLS phase of walking relative to healthy controls. These findings improve understanding of the complex functional consequences of hip OA and enhance our understanding of how to monitor the effectiveness of an intervention on biomechanical changes in gait in people with hip OA. • Individuals with mild to moderate hip OA use different muscle lower limb coordination strategies. • Differing coordination during gait may be a response to neuromuscular deficits such as strength. • Interventions targeting muscles associated with altered patterns of muscle coordination may be warranted. [ABSTRACT FROM AUTHOR]

Background: Femoroacetabular impingement syndrome is characterized by chondrolabral damage and hip pain. The specific biomechanics used by people with femoroacetabular impingement syndrome during daily activities may exacerbate their symptoms. Femoroacetabular impingement syndrome can be treated nonoperatively or surgically; however, differential treatment effects on walking biomechanics have not been examined. Purpose: To compare the 12-month effects of physical therapist–led care or arthroscopy on trunk, pelvis, and hip kinematics as well as hip moments during walking. Study Design: Secondary analysis of multi-centre, pragmatic, two-arm superiority randomized controlled trial subsample; Level of evidence, 1. Methods: A subsample of 43 participants from the Australian Full randomised controlled trial of Arthroscopic Surgery for Hip Impingement versus best cONventional (FASHIoN trial) underwent gait analysis and completed the International Hip Outcome Tool (iHOT-33) at both baseline and 12 months after random allocation to physical therapist–led care (personalized hip therapy; n = 22; mean age 35; 41% female) or arthroscopy (n = 21; mean age 36; 48% female). Changes in trunk, pelvis, and hip biomechanics were compared between treatment groups across the gait cycle using statistical parametric mapping. Associations between changes in iHOT-33 and changes in hip kinematics across 3 planes of motion were examined. Results: As compared with the arthroscopy group, the personalized hip therapy group increased its peak hip adduction moments (mean difference = 0.35 N·m/body weight·height [%] [95% CI, 0.05-0.65]; effect size = 0.72; P =.02). Hip adduction moments in the arthroscopy group were unchanged in response to treatment. No other between-group differences were detected. Improvements in iHOT-33 were not associated with changes in hip kinematics. Conclusion: Peak hip adduction moments were increased in the personalized hip therapy group and unchanged in the arthroscopy group. No biomechanical changes favoring arthroscopy were detected, suggesting that personalized hip therapy elicits greater changes in hip moments during walking at 12-month follow-up. Twelve-month changes in hip-related quality of life were not associated with changes in hip kinematics. [ABSTRACT FROM AUTHOR]

Purpose: This study aimed to determine if a preseason field-based test battery was prospectively associated with noncontact anterior cruciate ligament (ACL) injury in elite female footballers. Methods: In total, 322 elite senior and junior female Australian Rules Football and soccer players had their isometric hip adductor and abductor strength, eccentric knee flexor strength, countermovement jump (CMJ) kinetics, and single-leg hop kinematics assessed during the 2019 preseason. Demographic and injury history details were also collected. Footballers were subsequently followed for 18 months for ACL injury. Results: Fifteen noncontact ACL injuries occurred during the follow-up period. Prior ACL injury (odds ratio [OR], 9.68; 95% confidence interval (95% CI), 2.67–31.46), a lower isometric hip adductor to abductor strength ratio (OR, 1.98; 95% CI, 1.09–3.61), greater CMJ peak take-off force (OR, 1.74; 95% CI, 1.09–3.61), and greater single-leg triple vertical hop average dynamic knee valgus (OR, 1.97; 95% CI, 1.06–3.63) and ipsilateral trunk flexion (OR, 1.60; 95% CI, 1.01–2.55) were independently associated with an increased risk of subsequent ACL injury. A multivariable prediction model consisting of CMJ peak take-off force, dynamic knee valgus, and ACL injury history that was internally validated classified ACL injured from uninjured footballers with 78% total accuracy. Between-leg asymmetry in lower limb strength and CMJ kinetics were not associated with subsequent ACL injury risk. Conclusions: Preseason field-based measures of lower limb muscle strength and biomechanics were associated with future noncontact ACL injury in elite female footballers. These risk factors can be used to guide ACL injury screening practices and inform the design of targeted injury prevention training in elite female footballers. [ABSTRACT FROM AUTHOR]

To compare lower limb strength and countermovement jump (CMJ) kinetics between elite female footballers with and without a history of anterior cruciate ligament reconstruction (ACLR), hamstring strain, or hip/groin injury. Cross-sectional. Field-based. 369 elite female Australian football, soccer and rugby league players aged 15–35. Isometric hip adductor and abductor strength, eccentric knee flexor strength, and CMJ vertical ground reaction forces, including between-leg asymmetry. Players reported their lifetime history of ACLR, and whether they had sustained a hamstring strain, or hip/groin injury in the previous 12-months. Players with a unilateral history of ACLR (n = 24) had significant between-leg asymmetry in eccentric knee flexor strength (mean = −6.3%, 95%CI = −8.7 to −3.9%, P <.001), isometric hip abductor strength (mean = −2.5%, 95%CI = −4.3 to −0.7%, P =.008), and CMJ peak landing force (mean = −5.5%, 95%CI = −10.9 to −0.1%, P =.046). Together, between-leg asymmetry in eccentric knee flexor strength, isometric hip abductor strength, and CMJ peak landing force distinguished between players with and without prior ACLR with 93% accuracy. Elite female footballers with a history of ACLR, but not hamstring or hip/groin injury, exhibit persistent between-leg asymmetries in lower limb strength and jump kinetics following a return to sport. • Elite female footballers with prior ACLR display chronic between-leg asymmetries in knee flexor strength, hip abductor strength, and jump-landing force. • Lower limb strength and jump kinetics are not impaired after hamstring or hip/groin injury. • These data may have implications for ACLR rehabilitation and return to sport criteria. [ABSTRACT FROM AUTHOR]

Objectives: To quantify the changes in work done by lower limb joint moments during maximal speed running following a sports-specific repeated running protocol.Design: Observational with repeated-measures.Methods: Recreational athletes (n = 18 (9 females), aged = 26.2 ± 6.2 years) performed 12 maximal 30-m sprints on a non-motorised treadmill. Three-dimensional kinematics and ground reaction forces were subsequently recorded during a 10-m maximal overground sprint before and immediately after the repeated running protocol, from which we calculated work done by sagittal plane hip, knee, and ankle moments. Relative work (J/kg) was reported as a percentage of positive and negative work done by the sum of joint moments.Results: Following the repeated running protocol, maximal sprint speed decreased by 19% and was accompanied by reductions in total positive (-1.47 J/kg) and negative (-0.92 J/kg) work, in addition to work done by hip (-0.43 to -0.82 J/kg) and knee (-0.28 J/kg) moments during swing. Compared to before the repeated running protocol, less relative work was done by hip (-9%) and knee (-3%) extension moments during swing. Reductions in work done by hip and knee joint moments during swing were significantly correlated with reductions in maximum running speed (r = 0.61-0.89, p < 0.05).Conclusions: A sports-specific repeated running protocol resulted in reductions in mechanical work done by sagittal plane hip and knee joint moments during maximal overground sprinting. Interventions focused on maintaining positive work done by the hip flexors/extensors and negative work done by knee flexors/extensors during the swing phase of running may help prevent reductions in speed following repeated sprinting. [ABSTRACT FROM AUTHOR]

This study aimed to evaluate hip joint kinematic variability and segment coordination variability during walking according to pain and radiographic disease severity in people with hip osteoarthritis. Fifty‐five participants with hip osteoarthritis had pain severity assessed during walking using an item on the Western Ontario and McMasters Universities Osteoarthritis Index (no pain = 10; mild pain = 28; moderate pain = 17). Radiographic disease severity was graded by Kellgren and Lawrence scale (KL2 = 29; KL3 = 21; KL4 = 5). Hip kinematics variability was estimated as the curve coefficient of variation. Vector coding was used to calculate coordination variability for select joint couplings. One‐way analysis of variances with planned adjusted post hoc comparisons were used to compare hip kinematics variability and coordination variability of select segment couplings (pelvis sagittal vs thigh sagittal; pelvis frontal vs thigh frontal; pelvis transverse vs thigh transverse; thigh sagittal vs shank sagittal; thigh frontal vs shank sagittal; thigh transverse vs shank sagittal) according to pain and radiographic disease severity. No main effect of pain severity was observed for sagittal or transverse plane hip kinematic variability (P ≥.266), and although there was a main effect for frontal plane hip kinematic variability (P =.035), there were no significant differences when comparing between levels of pain severity (P >.006). There was no main effect of radiographic disease severity on hip kinematic variability in the sagittal (P =.539) or frontal (P =.307) plane. No significant differences in coordination of variability of segment couplings were observed (all P ≥.229). Movement variability as assessed in this study did not differ according to pain severity during walking or radiographic disease severity. [ABSTRACT FROM AUTHOR]

Hip-related pain can significantly impact quality of life, function, work capacity, physical activity and family life. Standardised measurement methods of physical capacity of relevance to young and middle-aged active adults with hip-related pain are currently not established. The aim of this consensus paper was to provide recommendations for clinical practice and research on standardised measurement methods of physical capacity in young and middle-aged active adults with hip-related pain. Four areas of importance were identified: (1) clinical measures (range of motion, muscle strength, functional impairments), (2) laboratory-based measures (biomechanics and muscle function (muscle activity, size and adiposity)), (3) physical activity, and (4) return to sport/performance. The literature was reviewed, and a summary circulated to the working group to inform discussion at the consensus meeting. The working group developed clinical and research recommendations from the literature review, which were further discussed and modified within the working group at the consensus meeting. These recommendations were then presented to all 38 International Hip-related Pain Research Network (IHiPRN) participants for further discussion, refinement and consensus voting. Therefore, the recommendations voted on were based on a combination of current evidence and expert opinion. The consensus meeting voted on 13 recommendations, six of which were clinically orientated, and seven more research specific. We recommended that clinicians working with young and middle-aged active adults with hip-related pain assess strength using objective methods of measurement, and clinically assess performance of functional tasks, including walking and running. Physical activity should be quantified using both self-reported and objective measures, and patient expectations of recovery should be quantified prior to treatment. It was recommended that return to physical activity (including sport and occupation) be quantified, and sport-specific activities should be assessed prior to return to sport. The IHiPRN participants were uncertain regarding recommendations for range of motion assessment. Research recommendations were that the measurement properties of range of motion, strength and functional performance tests be investigated, reported and improved in both clinical and research settings. Reporting of movement-related parameters (biomechanics and muscle function) should be standardised and the relationship among movement-related parameters, symptoms, function, quality of life, and intra-articular and imaging findings should be investigated. Quantification of return to physical activity (including sport and occupational demands) is required in future research, and the return to sport continuum should be used. Future research is required to determine the best criteria for rehabilitation progression and return to physical activity following hip-related pain management. [ABSTRACT FROM AUTHOR]

Femoroacetabular impingement (FAI) is a morphological hip condition that can cause hip/groin pain and impaired function in younger active adults, and may lead to stiffness, muscle weakness, structural damage, and hip osteoarthritis. Understanding the impairments associated with FAI is crucial to guide treatment and rehabilitation strategies. Evidence is limited and conflicting about whether hip biomechanics are impaired during walking in people with symptomatic FAI. The objective of this study was to determine whether kinematics and kinetics during gait differ between people with symptomatic FAI and control participants. Fifteen participants diagnosed with symptomatic cam-type or combined (cam plus pincer) FAI who were scheduled for arthroscopic surgery and 14 age-, and sex-matched disease-free controls underwent three-dimensional gait analysis. Tri-planar hip kinematics and kinetics were compared between the two groups. There were limited significant between-group differences with respect to spatiotemporal variables. Participants with FAI walked with less range of motion in the sagittal plane during a gait cycle, but did not exhibit any significant kinematic differences in the frontal or transverse planes. There were no systematic differences in kinetics between the groups in any plane. Findings suggest that individuals with symptomatic FAI have minimal impairments in gait biomechanics. Although these individuals demonstrate reduced hip joint motion in the sagittal plane, the size of the difference is small and its significance for symptoms and function is unclear. More pronounced deficits in hip kinetics and kinematics may be evident during functional tasks that challenge the hip towards the position of impingement. [ABSTRACT FROM AUTHOR]

Asymmetry during gait is associated with the evolution of secondary osteoarthritis. Kinematic asymmetry has been reported in advanced stages of hip osteoarthritis but has not been evaluated in earlier stages of the disease or has it been directly compared with unilateral and bilateral hip osteoarthritis. Our objective was to evaluate within-group symmetry and compare between-group asymmetry for three-dimensional pelvis, hip, knee, and ankle kinematics during walking and sit-to-stand in individuals with unilateral mild-to-moderate hip OA, bilateral mild-to-moderate hip osteoarthritis, and healthy controls. Twelve individuals with unilateral mild-to-moderate hip OA, nine individuals with bilateral mild-to-moderate symptomatic and radiographic hip OA, and 21 age-comparable healthy controls underwent three-dimensional motion analysis during walking and sit-to-stand. Pelvis and lower limb joint angles were calculated using inverse kinematics and between-limb symmetry was assessed for each group. Any resulting asymmetries (most affected minus contralateral limb) were compared between groups. Participants with unilateral hip osteoarthritis exhibited significantly less hip extension (7.90°), knee flexion (4.72°), and anterior pelvic tilt (3.38°) on their affected limb compared with the contralateral limb during the stance phase of walking. Those with unilateral hip osteoarthritis were significantly more asymmetrical than controls for sagittal plane hip and pelvis angles. No significant asymmetries were detected within- or between-groups for sit-to-stand. Individuals with unilateral hip osteoarthritis exhibited lower limb asymmetries consistent with those reported in advanced stages of disease during walking, but not sit-to-stand. Consideration of the possible negative effects of gait asymmetry on the health of the affected and other compensating joints appears warranted in the management of hip OA. [ABSTRACT FROM AUTHOR]

Purpose: Sprinting often provokes hip pain in individuals with femoroacetabular impingement syndrome (FAIS). Asphericity of the femoral head–neck junction (cam morphology) characteristic of FAIS can increase the risk of anterior–superior acetabular cartilage damage. This study aimed to 1) compare hip contact forces (magnitude and direction) during sprinting between individuals with FAIS, asymptomatic cam morphology (CAM), and controls without cam morphology, and 2) identify the phases of sprinting with high levels of anteriorly directed hip contact forces. Methods: Forty-six recreationally active individuals with comparable levels of physical activity were divided into three groups (FAIS, 14; CAM, 15; control, 17) based on their history of hip/groin pain, results of clinical impingement tests, and presence of cam morphology (alpha angle >55°). Three-dimensional marker trajectories, ground reaction forces, and electromyograms from 12 lower-limb muscles were recorded during 10-m overground sprinting trials. A linearly scaled electromyogram-informed neuromusculoskeletal model was used to calculate hip contact force magnitude (resultant, anterior–posterior, inferior–superior, medio-lateral) and angle (sagittal and frontal planes). Between-group comparisons were made using two-sample t -tests via statistical parametric mapping (P < 0.05). Results: No significant differences in magnitude or direction of hip contact forces were observed between FAIS and CAM or between FAIS and control groups during any phase of the sprint cycle. The highest anteriorly directed hip contact forces were observed during the initial swing phase of the sprint cycle. Conclusions: Hip contact forces during sprinting do not differentiate recreationally active individuals with FAIS from asymptomatic individuals with and without cam morphology. Hip loading during early swing, where peak anterior loading occurs, may be a potential mechanism for cartilage damage during sprinting-related sports in individuals with FAIS and/or asymptomatic cam morphology. [ABSTRACT FROM AUTHOR]

• Subject-specific passive knee kinematics can be automatically predicted from segmented medical images of knee anatomy. • Automatically determined geometric parameters of the kinematic models closely matched their manually determined counterparts. • The automatically generated kinematic models predicted tibiofemoral and patellofemoral kinematics comparable to their manual counterparts, while removing tedious manual processing and providing a systematic approach to model creation. Three-dimensional spatial mechanisms have been used to accurately predict passive knee kinematics, and have shown potential to be used in optimized multibody kinematic models. Such multi-body models are anatomically consistent and can accurately predict passive knee kinematics, but require extensive medical image processing and thus are not widely adopted. This study aimed to automate the generation of kinematic models of tibiofemoral (TFJ) and patellofemoral (PFJ) joints from segmented magnetic resonance imaging (MRI) and compare them against a corresponding manual pipeline. From segmented MRI of eight healthy participants (four females; aged 14.0 ± 2.6 years), geometric parameters (i.e., articular surfaces, ligament attachments) were determined both automatically and manually, and then assembled into TFJ and PFJ kinematic models to predict passive kinematics. The TFJ model was a six-link mechanism with deformable ligamentous constraints, whereas PFJ was a modified hinge. The ligament length changes through TFJ flexion were prescribed to literature strain profile. The geometric parameters were optimized to ensure physiological kinematic predictions through a Multiple Objective Particle Swarm Optimization. Geometric parameters showed strong agreement between automatic and manual pipelines (median error of 2.8 mm for anatomical landmarks and 1.5 mm for ligament lengths). Predicted TFJ and PFJ kinematics from the two pipelines were not statistically different, except for tibial superior/inferior translation near terminal TFJ extension. The TFJ kinematics predicted from the automatic pipeline had mean errors of 3.6° and 12.4° for adduction/abduction and internal/external rotation, respectively, and <7 mm mean translational error compared to the manual pipeline. Predicted PFJ had <9° mean rotational errors and <6 mm mean translational errors. The automatic pipeline developed and presented here can predict passive knee kinematics comparable to a manual pipeline, but removes laborious manual processing and provides a systematic approach to model creation. [ABSTRACT FROM AUTHOR]

Purpose: The magnitude and location of hip contact force influence the local mechanical environment of the articular tissue, driving remodeling. We used a neuromusculoskeletal model to investigate hip contact force magnitudes and their regional loading patterns on the articular surfaces in those with femoroacetabular impingement (FAI) syndrome and controls during walking. Methods: An EMG-assisted neuromusculoskeletal model was used to estimate hip contact forces in eligible participants with FAI syndrome (n = 41) and controls (n = 24), walking at self-selected speed. Hip contact forces were used to determine the average and spread of regional loading for femoral and acetabular articular surfaces. Hip contact force magnitude and region of loading were compared between groups using statistical parametric mapping and independent t -tests, respectively (P < 0.05). Results: All of the following findings are reported compared with controls. Those with FAI syndrome walked with lower-magnitude hip contact forces (mean difference, −0.7 N·BW−1; P < 0.001) during first and second halves of stance, and with lower anteroposterior, vertical, and mediolateral contact force vector components. Participants with FAI syndrome also had less between-participant variation in average regional loading, which was located more anteriorly (3.8°, P = 0.035) and laterally (2.2°, P = 0.01) on the acetabulum but more posteriorly (−4.8°, P = 0.01) on the femoral head. Participants with FAI syndrome had a smaller spread of regional loading across both the acetabulum (−1.9 mm, P = 0.049) and femoral head (1 mm, P < 0.001) during stance. Conclusions: Compared with controls, participants with FAI syndrome walked with lower-magnitude hip contact forces that were constrained to smaller regions on the acetabulum and femoral head. Differences in regional loading patterns might contribute to the mechanobiological processes driving cartilage maladaptation in those with FAI syndrome. [ABSTRACT FROM AUTHOR]

Background: Studies of walking in those with femoroacetabular impingement syndrome have found altered pelvis and hip biomechanics. But a whole body, time-contiuous, assessment of biomechanical parameters has not been reported. Additionally, larger cam morphology has been associated with more pain, faster progression to end-stage osteoarthritis and increased cartilage damage but differences in walking biomechanics between large compared to small cam morphologies have not been assessed.Research Question: Are trunk, pelvis and lower limb biomechanics different between healthy pain-free controls and individuals with FAI syndrome and are those biomechanics different between those with larger, compared to smaller, cam morphologies?Methods: Twenty four pain-free controls were compared against 41 participants with FAI syndrome who were stratified into two groups according to their maximum alpha angle. Participants underwent three-dimensional motion capture during walking. Trunk, pelvis, and lower limb biomechanics were compared between groups using statistical parametric mapping corrected for walking speed and pain.Results: Compared to pain-free controls, participants with FAI syndrome walked with more trunk anterior tilt (mean difference 7.6°, p < 0.001) as well as less pelvic rise (3°, p < 0.001), hip abduction (-4.6°, p < 0.05) and external rotation (-6.5°, p < 0.05). They also had lower hip flexion (-0.06Nm⋅kg-1, p < 0.05), abduction (-0.07Nm⋅kg-1, p < 0.05) and ankle plantarflexion moments (-0.19Nm⋅kg-1, p < 0.001). These biomechanical differences occurred throughout the gait cycle. There were no differences in walking biomechanics according to cam morphology size.Significance: Results do not support the hypothesis that larger cam morphology is associated with larger differences in walking biomechanics but did demonstrate general differences in trunk, pelvis and lower limb biomechanics between those with FAI sydrome and pain-free controls. Altered external biomechanics are likely the result of complex sensory-motor strategy resulting from pain inhibition or impingement avoidance. Future studies should examine internal loading in those with FAI sydnrome. [ABSTRACT FROM AUTHOR]

Background: Performance of the sit-to-stand (STS) task is compromised in individuals with advanced hip osteoarthritis (OA). Understanding how STS performance is altered in individuals with mild-to-moderate hip OA may inform interventions to improve function and slow disease progression.Research Question: Do trunk, pelvis, and hip biomechanics differ during a STS task between individuals with mild-to-moderate hip OA and a healthy, age-matched control group?Methods: Thirteen individuals with mild-to-moderate symptomatic and radiographic hip OA and seventeen healthy, age-matched controls performed a standardized STS task. Data were acquired using a three-dimensional motion capture system. The primary outcome measures were task duration, sagittal and frontal plane trunk, pelvis, and hip joint angles, and sagittal and frontal plane trunk and hip joint moments. Comparisons of lower-limb measures were between the most affected side in the hip OA group and a randomly chosen limb for the control group, termed the index limb, prior to and following lift-off from the chair.Results: Participants with mild-to-moderate hip OA took longer to perform the STS task compared to controls. Prior to lift-off, the hip OA group exhibited greater posterior pelvic tilt, greater pelvic rise on the index side and less hip joint flexion relative to controls. Following lift-off, the hip OA group exhibited greater pelvic rise on the index side compared to controls.Significance: Individuals with mild-to-moderate hip OA exhibit subtle alterations in movement strategy compared to healthy controls when completing a STS task similar, to a small extent, to adaptations reported in advanced stages of the disease. Interventions to target these features and prevent further decline in physical function may be warranted in the management of mild-to-moderate hip OA while the opportunity remains. [ABSTRACT FROM AUTHOR]

• Statistical shape models (SSM) of bones have been developed for adults, though these have limited applicability to paediatric populations. • SSM of paediatric lower limb bones were built and were capable of accurately reconstructing bone geometric models from anatomical landmarks. • The SSM can be used to reconstruct subject-specific bone geometry from readily accessible anatomical landmarks, avoiding the need for medical imaging. • The built paediatric SSM can reconstruct paediatric lower limb bones more accurately than adult-based SSM. Accurate representation of bone shape is important for subject-specific musculoskeletal models as it may influence modelling of joint kinematics, kinetics, and muscle dynamics. Statistical shape modelling is a method to estimate bone shape from minimal information, such as anatomical landmarks, and to avoid the time and cost associated with reconstructing bone shapes from comprehensive medical imaging. Statistical shape models (SSM) of lower limb bones have been developed and validated for adult populations but are not applicable to paediatric populations. This study aimed to develop SSM for paediatric lower limb bones and evaluate their reconstruction accuracy using sparse anatomical landmarks. We created three-dimensional models of 56 femurs, 29 pelves, 56 tibias, 56 fibulas, and 56 patellae through segmentation of magnetic resonance images taken from 29 typically developing children (15 females; 13 ± 3.5 years). The SSM for femur, pelvis, tibia, fibula, patella, haunch (i.e., combined femur and pelvis), and shank (i.e., combined tibia and fibula) were generated from manual segmentation of comprehensive magnetic resonance images to describe the shape variance of the cohort. We implemented a leave-one-out cross-validation method wherein SSM were used to reconstruct novel bones (i.e., those not included in SSM generation) using full- (i.e., full segmentation) and sparse- (i.e., anatomical landmarks) input, and then compared these reconstructions against bones segmented from magnetic resonance imaging. Reconstruction performance was evaluated using root mean squared errors (RMSE, mm), Jaccard index (0-1), Dice similarity coefficient (DSC) (0-1), and Hausdorff distance (mm). All results reported in this abstract are mean ± standard deviation. Femurs, pelves, tibias, fibulas, and patellae reconstructed via SSM using full-input had RMSE between 0.89 ± 0.10 mm (patella) and 1.98 ± 0.38 mm (pelvis), Jaccard indices between 0.77 ± 0.03 (pelvis) and 0.90 ± 0.02 (tibia), DSC between 0.87 ± 0.02 (pelvis) and 0.95 ± 0.01 (tibia), and Hausdorff distances between 2.45 ± 0.57 mm (patella) and 9.01 ± 2.36 mm (pelvis). Reconstruction using sparse-input had RMSE ranging from 1.33 ± 0.61 mm (patella) to 3.60 ± 1.05 mm (pelvis), Jaccard indices ranging from 0.59 ± 0.10 (pelvis) to 0.83 ± 0.03 (tibia), DSC ranging from 0.74 ± 0.08 (pelvis) to 0.90 ± 0.02 (tibia), and Hausdorff distances ranging from 3.21 ± 1.19 mm (patella) to 12.85 ± 3.24 mm (pelvis). The SSM of paediatric lower limb bones showed reconstruction accuracy consistent with previously developed SSM and outperformed adult-based SSM when used to reconstruct paediatric bones. [ABSTRACT FROM AUTHOR]