Search

Your search keyword '"Huang, Li‐Juan"' showing total 1 results
Start Over Author "Huang, Li‐Juan" Topic biomolecules
1 results on '"Huang, Li‐Juan"'

1. A global comparability approach for biosimilar monoclonal antibodies using LC–tandem MS based proteomics.

Author

Chen, Shun-Li, Wu, Shiaw-Lin, Huang, Li-Juan, Huang, Jia-Bao, and Chen, Shu-Hui

Subjects
*BIOMOLECULES, *MONOCLONAL antibodies, *TANDEM mass spectrometry, *PROTEOMICS, *COMPARATIVE studies, *TRASTUZUMAB
Abstract

Highlights: [•] A 3-step comparison strategy is demonstrated for biosimilars. [•] Comparisons include sequencing, targeted modifications and non-targeted tryptic map. [•] Anti-Her2 trastuzumab is compared with the correct and mutated biosimilars. [•] Non-targeted intensity comparisons are shown to correctly identify the variants. [•] The method provides extra-dimensional view to assess the complexity for biosimilars. [Copyright &y& Elsevier]

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results