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Reports on the syntheses of 2-amino-3,6-dihydroxynorbornanecarboxylic acid and 2-amino-3,5,6-trihydroxynorbornanecarboxylic acids. Properties of the 2-aminonorbornanecarboxylic acid derivatives; Cycloaddition reaction between oxazolone and cyclopentadiene; Intramolecular reaction of the carboxylic group with the epoxide; Methylene bridge formation.

Presents a synthesis of an oxazolone functionalized with the ethoxycarbonyloxy group on methylenic carbon, starting from 4-hydroxymethylenoxazolone and ethyl chlorocarbonate. Derivative of 2-aminonorbornane-2-carboxylic acids; Advantages of the ethoxycarbonyloxy group compared to chlorine atom; Direct introduction of the protected hydroxy group; Increased reactivity of the dienophile.

Studies the enantioselective synthesis of 2-amino-3-hydroxynorbornene-2-carboxylic acid derivatives using Diels-Alder reaction between cyclopentadiene and different dienophiles, operating with different Lewis acids and both with thermal and with ultrasound conditions. Control of cycloaddition reaction in favor of the exo and endo products; Catalysts used in the reactions.