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1. Are personality disorders in bipolar patients more frequent in the US than Europe?

2. Double jeopardy in the United States: Early onset bipolar disorder and treatment delay.

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3. More assortative mating in US compared to European parents and spouses of patients with bipolar disorder: implications for psychiatric illness in the offspring.

4. Adding Increased Energy or Activity to Criterion (A) of the DSM-5 Definition of Hypomania and Mania: Effect on the Diagnoses of 907 Patients From the Bipolar Collaborative Network.

5. Testing a clinical staging model for bipolar disorder using longitudinal life chart data.

6. Guidelines for the recognition and management of mixed depression.

7. Dysphoric mania, mixed states, and mania with mixed features specifier: are we mixing things up?

8. More childhood onset bipolar disorder in the United States than Canada or Europe: Implications for treatment and prevention.

9. Switch Rates During Acute Treatment for Bipolar II Depression With Lithium, Sertraline, or the Two Combined: A Randomized Double-Blind Comparison.

10. Illnesses in siblings of US patients with bipolar disorder relate to multigenerational family history and patients severity of illness.

11. Mixed Depression in Bipolar Disorder: Prevalence Rate and Clinical Correlates During Naturalistic Follow-Up in the Stanley Bipolar Network.

12. Age of onset of bipolar disorder: Combined effect of childhood adversity and familial loading of psychiatric disorders.

13. Age at Onset of Bipolar Disorder Related to Parental and Grandparental Illness Burden.

14. Further Evidence of a Cohort Effect in Bipolar Disorder: More Early Onsets and Family History of Psychiatric Illness in More Recent Epochs.

15. Clinical correlates of sustained response to individual drugs used in naturalistic treatment of patients with bipolar disorder.

16. More illness in offspring of bipolar patients from the U.S. compared to Europe.

17. Increases in multiple psychiatric disorders in parents and grandparents of patients with bipolar disorder from the USA compared with The Netherlands and Germany.

18. Multigenerational Positive Family History of Psychiatric Disorders Is Associated With a Poor Prognosis in Bipolar Disorder.

19. Verbal abuse, like physical and sexual abuse, in childhood is associated with an earlier onset and more difficult course of bipolar disorder.

20. Efficacy and safety of low- and high-dose cariprazine in acute and mixed mania associated with bipolar I disorder: a double-blind, placebo-controlled study.

21. Adjunctive lisdexamfetamine in bipolar depression: a preliminary randomized, placebo-controlled trial.

22. Relationship of clinical course of illness variables to medical comorbidities in 900 adult outpatients with bipolar disorder.

23. More pernicious course of bipolar disorder in the United States than in many European countries: implications for policy and treatment.

24. Monitoring pharmacotherapy response, safety, and tolerability to enhance adherence in bipolar disorder.

25. More medical comorbidities in patients with bipolar disorder from the United States than from the Netherlands and Germany.

26. Metabolic syndrome in bipolar disorder: a review with a focus on bipolar depression.

27. Heritability and linkage analysis of personality in bipolar disorder.

28. Heritability and genome-wide SNP linkage analysis of temperament in bipolar disorder.

29. Role of childhood adversity in the development of medical co-morbidities associated with bipolar disorder.

30. Association of dopamine transporter gene variants with childhood ADHD features in bipolar disorder.

31. Obesity in bipolar disorder: an overview.

32. Relationship of prior antidepressant exposure to long-term prospective outcome in bipolar I disorder outpatients.

33. Further evidence for linkage of bipolar disorder to chromosomes 6 and 17 in a new independent pedigree series.

34. Differential clinical characteristics, medication usage, and treatment response of bipolar disorder in the US versus The Netherlands and Germany.

35. Prevalence and correlates of eating disorders in 875 patients with bipolar disorder.

36. A randomized, placebo-controlled study of adjunctive ramelteon in ambulatory bipolar I disorder with manic symptoms and sleep disturbance.

37. Complexity of pharmacologic treatment required for sustained improvement in outpatients with bipolar disorder.

38. Early-onset bipolar disorder and treatment delay are risk factors for poor outcome in adulthood.

39. Placebo-controlled study of quetiapine monotherapy in ambulatory bipolar spectrum disorder with moderate-to-severe hypomania or mild mania.

40. Gender and depressive symptoms in 711 patients with bipolar disorder evaluated prospectively in the Stanley Foundation bipolar treatment outcome network.

41. Randomized, double-blind, placebo-controlled study of divalproex extended release loading monotherapy in ambulatory bipolar spectrum disorder patients with moderate-to-severe hypomania or mild mania.

42. Suggestive evidence for linkage of ADHD features in bipolar disorder to chromosome 10p14.

43. Memantine efficacy and safety in patients with acute mania associated with bipolar I disorder: a pilot evaluation.

44. Olanzapine/fluoxetine combination vs. lamotrigine in the 6-month treatment of bipolar I depression.

45. Long-term safety and efficacy of ziprasidone in subpopulations of patients with bipolar mania.

46. Randomized, placebo-controlled trial of risperidone for acute treatment of bipolar anxiety.

47. Impact of antidepressant continuation after acute positive or partial treatment response for bipolar depression: a blinded, randomized study.

48. Correlates of treatment-emergent mania associated with antidepressant treatment in bipolar depression.

49. Characterizing impulsivity in mania.

50. Aripiprazole monotherapy in the treatment of acute bipolar I mania: a randomized, double-blind, placebo- and lithium-controlled study.