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Abstract: The formation and evolution of Silurian sandstone reservoirs, which are characterized by the coexistence of reservoir bitumen with different types of commercial oil pools in a very extensive area around the slope and uplift areas of the Manjiaer Depression in the Tarim Basin, NW China, are still in question. In this paper we report our investigations on the geological and geochemical characteristics of this reservoir. The results show there are four types of oil shows in the reservoir: severely biodegraded solid bitumen, biodegraded heavy oil, normal oils and light oils with slight biodegradation. Three suites of petroleum inclusions were identified in the reservoir which were formed during the early Devonian, Triassic to Cretaceous and late Tertiary, respectively. Petroleum in the Silurian sandstone reservoirs mainly originated from the mid-lower Cambrian source rock and mid-upper Ordovician source rock. The thermal maturity evolution of the source rocks in slope areas has shown that there were three main stages of oil generation that controlled the formation of the above three stages of petroleum inclusions. This evidence indicates that the Silurian reservoir has experienced three petroleum charge events during its geological history. The first charge event occurred during the early Devonian and it resulted in giant paleo-pools, which gradually evolved into the presently widespread bitumen due to the combination of biodegradation and thermal alteration. The second charge covered a long period from Triassic to Cretaceous and probably was related to both the mid-lower Cambrian source rock and the mid-upper Ordovician source rock. The petroleum generated during this stage mixed and interacted with the low matured residual bitumen and eventually formed the present soft bitumen and some residual heavy oils in the reservoirs. The third charge event, mainly associated with the mid-upper Ordovician source rocks, occurred mainly during late Tertiary and accounted for most of the present commercial petroleum pools (mainly normal and light oils). [Copyright &y& Elsevier]