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Within the DEMO first wall 3D shape design activity, studying the effect of misalignment started in 2017. Such assessments have been conducted in the past for ITER and heat flux penalty factor maps have been created [ 1 ]; this route could be a feasible approach in the case of DEMO as well. This paper details the methodology that allows the effects of misalignments to be assessed for DEMO. The test cases focus on steady-state plasma operation (start of flat top). The aim is to understand the effect of basic misaligned cases, for example radial protrusion/recession or poloidal rotation of a single module. To do so, particle tracing software codes such as SMARDDA and PFCflux have been used to create heat flux maps that reach the first wall surfaces. These heat flux maps, combined with the specified radiative heat load, are used as input for simplified FE models of the blanket modules. As a result, not only the effect on heat flux, but also on the temperature (and later stress) distributions can be estimated. The paper describes how the obtained results can be implemented in ANSYS in the identified critical cases from the test matrix that has been studied. The results obtained from the nominal heat flux map are compared to the misaligned cases. The mitigating effect of the 3D nature of the heat conduction on the peak temperature is discussed. This work paves the way to assessing more realistic combined misaligned cases (such as misalignment from different thermal expansion, or due to electromagnetic loads etc. of neighbouring blankets) in the future. [ABSTRACT FROM AUTHOR]