6 results on '"Ouattara S"'
Search Results
2. Importance of extending the use of polymerase chain reaction in the diagnosis of venereal syphilis in a blood transfusion center in Burkina Faso, West Africa.
- Author
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Simpore A, Bisseye C, Nagalo BM, Sanou M, Nébié Y, Ghoma-Linguissi LS, Dahourou H, Sawadogo B, Djigma F, Ouattara S, Pietra V, Nichol J, and Simpore J
- Subjects
- Adolescent, Adult, Burkina Faso epidemiology, Female, Humans, Male, Middle Aged, Prevalence, Syphilis epidemiology, Treponema pallidum isolation & purification, Young Adult, Blood Donors, Polymerase Chain Reaction methods, Syphilis diagnosis, Syphilis Serodiagnosis methods
- Abstract
Introduction: Due to the existence of a variety of types of non-venereal syphilis caused by the related T. pallidum, regular serological testing such as Rapid Plasma Reagin (RPR) and Chemiluminescent Microparticle Immunoassay Technique (CMIA) are often unable to differentiate venereal syphilis from the non- venereal one, hence, the interest in the use of molecular biology testing for a confirmation diagnosis of syphilis caused by Treponema pallidum subspecies pallidum., Objective: The study is designed to assess the effectiveness of PCR testing and serological methods in the diagnosis of Treponema pallidum subsp pallidum among blood donors in Burkina Faso., Methods: The study included 6375 samples of volunteer blood donors from the regional blood transfusion center of Ouagadougou (CRTS/O). Among samples, 183 positive and 59 negative in RPR were analyzed to detect antibodies anti-T. pallidum subsp pallidum with a immunoassay method (CMIA) and were confirmed using the Polymerase Chain Reaction testing., Results: In RPR, we obtained a prevalence rate of 2.9% (183/6375) for treponematosis. From the 183 RPR+ specimen, 108 (59%) were found CMIA+ and 11 (6%) were confirmed PCR+. While the 59 pattern RPR-; 31 (52.5%) were CMIA + including 3 (5.1%) tested PCR+. Seventy-five (75) samples RPR + /CMIA-; 2 (2.7%) were confirmed positive by PCR. All 28 samples RPR-/CMIA- were confirmed negative by PCR., Conclusion: PCR testing confirmed a low distribution of T. pallidum subsp pallidum in comparison to serological methods. Cross-reactions, existence of non-venereal treponemal or immunological scars could account for the discrepancy between the results obtained.
- Published
- 2014
- Full Text
- View/download PDF
3. Transfusion safety in francophone African countries: an analysis of strategies for the medical selection of blood donors.
- Author
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Tagny CT, Kouao MD, Touré H, Gargouri J, Fazul AS, Ouattara S, Anani L, Othmani H, Feteke L, Dahourou H, Mbensa GO, Molé S, Nébié Y, Mbangue M, Toukam M, Boulahi MO, Andriambelo LV, Rakoto O, Baby M, Yahaya R, Bokilo A, Senyana F, Mbanya D, Shiboski C, Murphy EL, and Lefrère JJ
- Subjects
- Adult, Africa, Blood Banks statistics & numerical data, Female, Humans, Male, Blood Donors statistics & numerical data, Blood Transfusion statistics & numerical data, Donor Selection methods, Donor Selection standards
- Abstract
Background: The goal of selecting a healthy blood donor is to safeguard donors and reduce the risks of infections and immunologic complications for recipients., Study Design and Methods: To evaluate the blood donor selection process, a survey was conducted in 28 blood transfusion centers located in 15 francophone African countries. Data collected included availability of blood products, risk factors for infection identified among blood donor candidates, the processing of the information collected before blood collection, the review process for the medical history of blood donor candidates, and deferral criteria for donor candidates., Results: During the year 2009, participating transfusion centers identified 366,924 blood donor candidates. A mean of 13% (range, 0%-36%) of the donor candidates were excluded based solely on their medical status. The main risk factors for blood-borne infections were having multiple sex partners, sexual intercourse with occasional partners, and religious scarification. Most transfusion centers collected this information verbally instead of having a written questionnaire. The topics least addressed were the possible complications relating to the donation, religious scarifications, and history of sickle cell anemia and hemorrhage. Only three centers recorded the temperature of the blood donors. The deferral criteria least reported were sickle cell anemia, piercing, scarification, and tattoo., Conclusions: The medical selection process was not performed systemically and thoroughly enough, given the regional epidemiologic risks. It is essential to identify the risk factors specific to francophone African countries and modify the current medical history questionnaires to develop a more effective and relevant selection process., (© 2011 American Association of Blood Banks.)
- Published
- 2012
- Full Text
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4. Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses and syphilis among blood donors in Koudougou (Burkina Faso) in 2009.
- Author
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Nagalo MB, Sanou M, Bisseye C, Kaboré MI, Nebie YK, Kienou K, Kiba A, Dahourou H, Ouattara S, Zongo JD, and Simporé J
- Subjects
- Adult, Burkina Faso epidemiology, Female, HIV Infections blood, Hepatitis B blood, Hepatitis C blood, Humans, Male, Retrospective Studies, Risk Factors, Seroepidemiologic Studies, Syphilis blood, Young Adult, Blood Donors statistics & numerical data, HIV Infections epidemiology, HIV Seroprevalence, Hepatitis B epidemiology, Hepatitis C epidemiology, Syphilis epidemiology
- Abstract
Background: The high prevalence of numerous transfusion-transmitted infectious diseases such as human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV) and syphilis in sub-Saharan Africa affects the safety of blood for recipients. This study was undertaken with the aim of determining the seroprevalence of HIV, HCV, HBV, syphilis and socio-demographic risk factors associated with blood donation in a new regional blood transfusion centre in Burkina Faso., Material and Methods: Sera samples were screened for hepatitis B surface antigen (HBsAg), antibodies to HCV, HIV types 1 and 2 and to Treponema pallidum using enzyme-linked immunosorbent assays and Rapid Plasma Reagin test (RPR) respectively. All the reactive samples for HIV, HBsAg, and HCV were confirmed using a second enzyme-linked immunosorbent assays. Antibodies to Treponema pallidum were confirmed with a Treponema pallidum haemagglutination test (TPHA)., Results: From the total of 4,520 blood donors in 2009, 1,348 (29.82%) were infected with at least one pathogen and 149 (3.30%) had serological evidence of multiple infections. The overall seroprevalence rate of HIV, HBV, HCV and syphilis was 2.21%, 14.96%, 8.69% and 3.96%, respectively. Among blood donors with multiples infections, the most common dual or triple combinations were HBsAg-HCV (1.39%), HBsAg-syphilis (0.66%) and HBsAg-HCV-syphilis (0.11%). The highest prevalences of HBsAg and HIV were found among blood donors from rural areas and in the age groups of 20-29 years and >40 years old, respectively., Conclusion: HBV and HCV remain the greatest threats to blood safety in Burkina Faso. Strict selection and retention of voluntary, non-remunerated low-risk blood donors are recommended to improve blood safety in the regional blood transfusion centre of Koudougou.
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- 2011
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5. [Lack of knowledge among blood donors in Burkina Faso (West Africa); potential obstacle to transfusion security].
- Author
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Nébié KY, Olinger CM, Kafando E, Dahourou H, Diallo S, Kientega Y, Domo Y, Kienou K, Ouattara S, Sawadogo I, Ky L, and Muller CP
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- Adolescent, Adult, Blood-Borne Pathogens, Burkina Faso epidemiology, Communicable Diseases transmission, Cross-Sectional Studies, Educational Status, Female, HIV Infections epidemiology, HIV Infections prevention & control, HIV Infections psychology, HIV Infections transmission, Hepatitis, Viral, Human epidemiology, Hepatitis, Viral, Human prevention & control, Hepatitis, Viral, Human psychology, Hepatitis, Viral, Human transmission, Humans, Male, Middle Aged, Motivation, Risk Factors, Surveys and Questionnaires, Transfusion Reaction, Blood Donors psychology, Blood Transfusion psychology, Communicable Diseases psychology, Disease Transmission, Infectious prevention & control, Health Knowledge, Attitudes, Practice
- Abstract
Background: The measures recommended to reduce TTD include clinical selection of donors, based on a standardized questionnaire which aims to find out antecedents and behaviours predicting transmitted diseases within donors. The effectiveness of this measure is well established in the industrialized countries where the level of education of the population may support a greater receptivity of donors about this procedure. What is happening in developing one?, Aim: This study was carried out to assess knowledge attitude and behaviours among blood donors regarding blood and transfusion safety in Burkina Faso., Methods: A cross sectional study was carried out in the blood bank of the teaching hospital of Ouagadougou. In addition to the routine questionnaire, 544 included blood donors were subjected to additional questions seeking to specify their behaviours, knowledge and attitude towards TTD diseases and screening., Results: Donors were from 16 to 57 years of age (mean age : 28+/-7.9 years). The majority of donors were male (71.2%). Family donors represent 52% and first time donors 55%. About 30.8% were illiterate or of primary school level. A percentage of 14.4 donate to access HIV testing and 30.7% will donate blood immediately to check any contamination in case of exposure. There was no difference between donors having been informed about their HIV status in the past and the other donors regarding HIV, HBs Ag and VHC results., Conclusions: This study suggests that there is some great need for donors' education on transfusion safety. There is also need for staff training in donors' management.
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- 2007
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6. Updated characteristics of blood services, donors and blood products in 11 French‐speaking African countries.
- Author
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Tagny, Claude T., Laperche, Syria, Murphy, Edward L., Ahlonsou, F, Anani, L, Atinkpinda, G, Lafia, E, Totongnon, R, Coulibaly, S, Dahourou, H, Diallo, S, Madingar, P, Domo, Y, Hermann, Z, Kabore, I, Kiba Koumare, A, Kientega, Y, Nebie, Y, Ouattara, S, and Sanou, M
- Subjects
BLOOD donors ,BLOOD products ,BLOOD transfusion ,BLOOD banks - Abstract
Background and objectives: The Francophone Africa Transfusion Research Network conducted the first large and comprehensive surveys on the status of blood safety in francophone African countries in 2009 and 2012. Since then, there has been substantial investment in blood safety but little is known about progress made in the region. Materials and Methods: This multicentre cross‐sectional study describes characteristics of blood services, donors and blood products and compares results with previous data. A web‐based questionnaire collected data of 2016 from 38 blood facilities in 11 French‐speaking countries. Data were analysed according to type of blood services and compared to similar studies conducted in 2009 and 2012. Results: The study included data on 572 933 donations from 366 844 donors. Compared to 2012, there was an increase in the median proportion of voluntary nonremunerated blood donation (+22%) (P = 0·004), and a reduction from 2·1 to 0·9 (P = 0·01), from 10·3 to 6·7 (P = 0·00), from 3·2 to 1·3 (P = 0·006) and from 1 to 0·4 (P = 0·03) in median seroprevalences of HIV, HBV, HCV and syphilis, respectively. The median proportion of blood orders fulfilled decreased (−18·2%) (P = 0·001). The number of technical staff per 1000 donations ranged from 1 to 54 with hospital‐based blood transfusion services having 12‐fold more staff than National and Regional services. Conclusion: Several indicators have improved in Francophone Africa Blood services during the last 5 years and national and regional services likely have better indicators than hospital‐based services. These findings may support the need for ongoing blood safety initiatives. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
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