Search

Your search keyword '"Heiner, D. C."' showing total 3 results
Start Over Author "Heiner, D. C." Topic blood proteins
3 results on '"Heiner, D. C."'

1. SERUM TRANSCORTIN LEVELS IN ACUTE LEUKEMIA.

Author

BEIER FR, LAHEY ME, and HEINER DC

Subjects
Child, Female, Humans, Infant, Infant, Newborn, Pregnancy, Adrenal Cortex Hormones, Blood Proteins, Ceruloplasmin, Immunoelectrophoresis, Leukemia, Transcortin, Transferrin, gamma-Globulins
Published
1963
Full Text
View/download PDF

3. Studies of complement activation and IgG subclass restriction of anti--thyroglobulin.

Author

Adler, T. R., Beall, G. N., Curd, J. G., Heiner, D. C., and Sabharwal, U. K.

Subjects
IMMUNOGLOBULINS, ENZYME activation, IMMUNOASSAY, GLYCOPROTEINS, AUTOANTIBODIES, BLOOD proteins
Abstract

Using a sensitive radioimmunoassay, it was demonstrated that autoantibodies to human thyroglobulin (hTg) did not activate complement upon interaction with solid phase adsorbed hTg. Since IgG4 immunoglobulins do not activate complement, we studied sera containing large amounts of anti-thyroglobulin (anti-Tg) with a sensitive radioimmunoassay for IgG4 anti-Tg. Antibodies of the IgG4 subclass were detected in the sera of each of the eight patients studied and not in control subjects. Quantitative assays of IgG4 anti-Tg were performed by comparing the removal of anti-Tg and total IgG4 during immunoadsorption of anti-Tg. The contribution of IgG4 anti-Tg antibodies to the total quantity of anti-Tg ranged from 6 to 30%, an amount inadequate to explain the lack of complement activation by anti-Tg. [ABSTRACT FROM AUTHOR]

Published
1984

Catalog

Books, media, physical & digital resources
See catalog results