Search

Biphasic calcium phosphate (BCP) is an important research field based on calcium phosphate biomaterials. In this paper, a new synthesis method of CDHA/α-TCP BCP was studied. By controlling the addition amount of citric acid, the relative contents of CDHA and α-TCP in the BCP were controlled. BCP bone cement was prepared with different proportions of BCP as raw materials. The BCP bone cement was characterized by XRD and SEM, and evaluated by measuring setting time, compressive strength, SBF immersion, and colorimetric CCK-8 assay. The results showed that the increase of CDHA content can lead to the reduction of the setting time of bone cement and delay the degradation rate of BCP bone cement. [ABSTRACT FROM AUTHOR]

Strontium has been widely used in bone repair materials due to its roles in promoting osteoclast apoptosis and enhancing osteoblast proliferation. In this work, synthesis and the effects of Sr2+ doping α-tricalcium phosphate at low-temperature was studied. The setting time and the mechanical properties of α-tricalcium phosphate were controlled by varying the content of Sr2+. The synthesized compounds were evaluated by XRD, SEM, XPS, setting time, compressive strength, SBF immersion, and colorimetric CCK-8 assay. The results showed that Sr2+ can improve the compressive strength and cell activity of calcium phosphate bone cement. [ABSTRACT FROM AUTHOR]

In this work, the setting process of reduced graphene (RGO)/carbon nanotubes (CNTs) reinforced calcium phosphate cement (CPC) were conducted in a microwave environment. The introduction of microwave can increase the reaction temperature, speed up the vibration of water molecules and eliminate bubbles from the interface between RGO, CNTs and the substrate. Comparing with CPC without microwave treatment, the final setting time of composites after microwave treatment are almost a half, the flexural strength and the compressive strength are increased by 19.86% and 21.68% respectively, which are 17.38 MPa and 104.52 MPa. Meanwhile, the CPC composites remain the excellent bioactivity. [ABSTRACT FROM AUTHOR]