1. Effects of caffeine, vitamin D, and other nutrients on quantitative phalangeal bone ultrasound in postmenopausal women.
- Author
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Rico H, Canal ML, Mañas P, Lavado JM, Costa C, and Pedrera JD
- Subjects
- Body Mass Index, Bone and Bones drug effects, Caffeine administration & dosage, Calcium, Dietary administration & dosage, Cohort Studies, Dietary Proteins administration & dosage, Female, Hand diagnostic imaging, Humans, Middle Aged, Regression Analysis, Ultrasonography, Vitamin D administration & dosage, Bone Density drug effects, Bone and Bones diagnostic imaging, Caffeine pharmacology, Calcium, Dietary pharmacology, Postmenopause physiology, Vitamin D pharmacology
- Abstract
Objective: We investigated the controversial effects of coffee and other nutrients on bone mass., Methods: In a study of 93 healthy postmenopausal women (mean +/- standard deviation: 57.3 +/- 7.1 y old and 8.9 +/- 7.5 y since menopause) selected on the basis of not having changed their eating habits since premenopause, not smoking, not exercising, not receiving hormone-replacement therapy, and having a weight in the range of 70% to 130% of their ideal weights, amplitude-dependent speed of sound (Ad-SOS) was determined by quantitative bone ultrasound, and a prospective 7-d diet survey evaluated the intake of caffeine and nutrients involved in calcium metabolism. Women were stratified according to their caffeine, calcium, and vitamin D intakes and ratios of calcium to phosphorus and to protein. Ad-SOS differed only with vitamin D intake and was greater in the group taking at leasst 400 IU/d (P < 0.0001)., Results: In simple and multiple regression analyses, the only significant variable that affected Ad-SOS and nutrient intake was vitamin D (P < 0.0001). Phalangeal bone Ad-SOS was influenced only by the intake of vitamin D, not of caffeine or other nutrients., Conclusions: This lack of effect of caffeine and protein may be related to good nutritional intake or the low levels of caffeine consumed.
- Published
- 2002
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