1. A Rare Presentation of Acute Myelogenous Leukemia: A Case Report of Vaginal and Uterine Myeloid Sarcoma from Iran.
- Author
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Salari, Sina, Darakhshandeh, Ali, Shahaboddini, Roohollah Gholampour, and Moghaddas, Azadeh
- Subjects
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ACUTE myeloid leukemia diagnosis , *ACUTE myeloid leukemia treatment , *UTERINE hemorrhage , *BIOPSY , *BONE marrow transplantation , *IMMUNOHISTOCHEMISTRY , *CANCER chemotherapy , *MYELOID sarcoma , *TREATMENT effectiveness , *BONE marrow , *EARLY diagnosis , *DISEASE management - Abstract
Myeloid or granulocytic sarcoma is an extramedullary tumor of immature granulocytic cells. This condition is rare and has a challenging diagnosis, relying on a high index of suspicion as well as radiology, histology, immunophenotyping, and molecular analyses. We herein report a case of a 25-year-old woman presented with vaginal bleeding and a large pelvic mass involving the vaginal and uterus. A biopsy and immunohistochemical examination of the mass revealed granulocytic sarcoma, and a subsequent bone marrow biopsy confirmed the diagnosis of acute myelogenous leukemia. The patient was treated based on the standard chemotherapy followed by allogeneic bone marrow transplantation from her full-matched sibling donor. After a 9-months follow-up, there was no notable complication, and the patient is now completely disease-free. Granulocytic sarcoma of the cervix is rare, and awareness of this entity is required for timely diagnosis and effective treatment. [ABSTRACT FROM AUTHOR]
- Published
- 2019