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Your search keyword '"Dai, Ru-Chun"' showing total 8 results
Start Over Author "Dai, Ru-Chun" Topic bone mineral density
8 results on '"Dai, Ru-Chun"'

1. A phase III randomized, double-blind, placebo-controlled trial of the denosumab biosimilar QL1206 in postmenopausal Chinese women with osteoporosis and high fracture risk

Author

Zhang, Hao, Gu, Jie-mei, Chao, Ai-jun, Cheng, Qun, Teng, Dong-hui, Yu, Jin-ming, Wang, Bing-wu, Huo, Ya-nan, Mao, Li, Zhang, Qiu, Yang, Hong, Yan, Shi-gui, Zhang, Ke-qin, Zhao, Xue-ling, Lin, Hua, Pei, Yu, Yuan, Zhong, Dai, Ru-chun, He, Liang, Chen, Li, Su, Yong-feng, Deng, Zhong-liang, You, Li, Ban, Bo, Zhu, Mei, Cao, You-liang, Zhu, Yi-kun, Li, Zhi-jun, Zhang, Zhi, Yi, Cheng-qing, Lu, Yi-bing, Wang, Guang, Han, Cui-cui, Wang, Zhen-jiang, Li, Xian-xing, and Zhang, Zhen-lin

Published
2023
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8. Quantitative associations between osteocyte density and biomechanics, microcrack and microstructure in OVX rats vertebral trabeculae

Author

Ma, Yu-Lin, Dai, Ru-Chun, Sheng, Zhi-Feng, Jin, Yan, Zhang, Yu-Hai, Fang, Ling-Na, Fan, Hui-Jie, and Liao, Er-Yuan

Subjects
*DENSITY, *PROPERTIES of matter, *ATMOSPHERIC density, *MICROMECHANICS
Abstract

Abstract: Osteocytes actively regulate bone modeling and remodeling, direct skeletal mineralization, and regulate calcium/phosphate homeostasis and extracellular matrix metabolism; yet the specific role of osteocytes in maintaining bone structural integrity and strength is unknown. Studies have shown that the density of osteocytes decreases with age and estrogen deficiency, as seen in postmenopausal women. Here, we examined the relationships between osteocyte density and the related variables, including biomechanics, bone mineral density, microcrack and microstructure of vertebral trabeculae, in ovariectomized rats. We found that osteocyte density correlated with some of the parameters that determine the biomechanical quality of bone. Our findings suggest that osteocytes could play a crucial role in maintaining the mechanical quality of bone, and osteocyte density could be considered as an alternative index in assessing bone quality. [Copyright &y& Elsevier]

Published
2008
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