8 results on '"Fabris G"'
Search Results
2. Volume changes of autogenous bone grafts after alveolar ridge augmentation of atrophic maxillae and mandibles.
- Author
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Sbordone L, Toti P, Menchini-Fabris GB, Sbordone C, Piombino P, and Guidetti F
- Subjects
- Adult, Alveolar Bone Loss, Chin surgery, Female, Humans, Ilium surgery, Male, Mandibular Diseases diagnostic imaging, Mandibular Diseases surgery, Maxillary Diseases diagnostic imaging, Maxillary Diseases surgery, Middle Aged, Radiography, Retrospective Studies, Alveolar Ridge Augmentation methods, Bone Density, Bone Remodeling, Bone Transplantation pathology, Dental Implantation, Endosseous
- Abstract
The aim of the present retrospective chart review was to determine the relationship between nonvascularized osseous graft remodeling and the three-dimensional (3D) features of grafts and recipient sites, the anatomical recipient regions and different graft sources. 32 iliac crest or chin grafts were onlay-positioned in the mandible or maxilla of 14 patients. CT scans, taken before implant positioning and after 1 year, revealed a mean volume resorption of 35-51%. For iliac crest grafts, the average resorption was 42% when the onlay was positioned in the anterior maxilla and 59% when it was positioned in the posterior mandible. Spearman correlation and 3D interpolation analysis revealed, for both iliac crest groups, a moderate or advanced remodeling pattern depending on 3D features, namely graft thickness and shape, basal bone volume of recipient site, and the basal bone/graft volume ratio of the recipient site. No statistically significant differences were found between the recipient and donor site groups. Retrospective analysis of the data indicates that iliac crest grafts, onlay-positioned on adequate basal bone volume, may register a reduced volume remodeling when shaped thick in the anterior maxilla or rounded and convex, on the external surface, in the posterior mandible.
- Published
- 2009
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3. Implant survival in maxillary and mandibular osseous onlay grafts and native bone: a 3-year clinical and computerized tomographic follow-up.
- Author
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Sbordone L, Toti P, Menchini-Fabris G, Sbordone C, and Guidetti F
- Subjects
- Adolescent, Adult, Aged, Atrophy, Bone Remodeling physiology, Bone Resorption etiology, Bone Transplantation diagnostic imaging, Chin, Dental Prosthesis Design, Female, Follow-Up Studies, Humans, Ilium, Jaw, Edentulous diagnostic imaging, Jaw, Edentulous pathology, Jaw, Edentulous surgery, Male, Mandible diagnostic imaging, Mandible pathology, Maxilla diagnostic imaging, Maxilla pathology, Middle Aged, Postoperative Complications, Plastic Surgery Procedures methods, Retrospective Studies, Survival Analysis, Tissue and Organ Harvesting methods, Treatment Outcome, Young Adult, Alveolar Ridge Augmentation methods, Bone Transplantation pathology, Dental Implantation, Endosseous methods, Dental Implants, Mandible surgery, Maxilla surgery, Tomography, X-Ray Computed
- Abstract
Purpose: This article discusses a 3-year retrospective survey of implant clinical survival and computerized tomographic analysis of bone remodeling in atrophic alveolar crests reconstructed via various autogenous bone grafting procedures and in similar regions of native bone., Materials and Methods: The retrospective chart review included consecutive edentulous patients with severe alveolar crest atrophy treated between 2000 and 2002 with onlay autogenous bone grafts in the mandible and anterior maxilla (as needed) and implant insertion. Implant recipients were followed for 3 years. Defective areas were reconstructed by bone graft harvested from the chin or iliac crest. Implants in reconstructed areas were divided into two groups according to graft source. Implants in corresponding native areas served as controls. Cumulative survival rate (CSR), survival rate, and confidence interval (CI) were calculated, and linear measurements of bone remodeling around implants were assessed on computerized tomographic scans. Results were compared for statistically significant differences by Wilcoxon signed-rank test with a significance level a = .05., Results: Forty patients were treated with 109 screw-type, root-form, rough-surfaced implants inserted in 48 onlay grafts; 88 implants were placed in native bone. The implant 3-year CSRs were 98.9% (CI 96.7% to 100%) in native bone and 99.1% (CI 97.3% to 100%) in onlay grafts, irrespective of bone source. Mean resorption in the maxilla was 4.6 +/- 0.9 mm buccally and 3.8 +/- 0.8 mm palatally in areas reconstructed with chin grafts, 3.4 +/- 1.7 mm buccally and 2.6 +/- 1.4 mm palatally in areas reconstructed with iliac crest grafts, and 3.2 +/- 1.2 mm buccally and 2.1 +/- 0.9 mm palatally in native areas., Conclusions: Similar implant CSRs were seen in native and grafted sites. Maximal implant CSR was observed in onlay grafts from the chin despite more marked linear bone remodeling in this group as compared to iliac crest grafts or native bone.
- Published
- 2009
4. Implant success in sinus-lifted maxillae and native bone: a 3-year clinical and computerized tomographic follow-up.
- Author
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Sbordone L, Toti P, Menchini-Fabris G, Sbordone C, and Guidetti F
- Subjects
- Adult, Dental Implantation, Endosseous methods, Dental Implants, Dental Restoration Failure, Female, Follow-Up Studies, Humans, Ilium transplantation, Male, Mandible transplantation, Maxilla diagnostic imaging, Maxillary Sinus diagnostic imaging, Middle Aged, Retrospective Studies, Tomography, X-Ray Computed, Treatment Outcome, Young Adult, Alveolar Ridge Augmentation methods, Bone Remodeling physiology, Bone Transplantation methods, Maxilla surgery, Maxillary Sinus surgery, Osseointegration physiology
- Abstract
Purpose: The present study was a 3-year follow-up evaluation of implant clinical success and radiographic bone remodeling in sinus floors elevated with different autogenous bone-grafting procedures and in similar native bone regions., Materials and Methods: This retrospective chart review examined consecutive edentulous patients with severe jaw atrophy treated between 2000 and 2002 via sinus lift, when needed, and implant insertion. Implants in sinus lift areas were divided into four groups by graft source (iliac crest, chin area) and technique (bone block, particulate). Implants positioned in native areas beneath the sinus floor served as controls. The cumulative success rate (CSR) and success rate (SR) were calculated, and linear measurements of bone remodeling around implants were assessed on computerized tomographic scans. Results were statistically compared with the Wilcoxon signed rank test., Results: Twenty-eight patients were treated in the posterior maxilla via insertion of 70 screw-type, root-form, rough implants in 39 sinus-lifted areas. All surgical procedures were uneventful. Twenty-four implants were positioned in native areas beneath the sinus floor. The implant CSR was 95.8% in native areas (one failure/24 implants), 85% in sinuses lifted with particulate chin bone (three failures/20 implants), and 100% in the other three groups (eight in particulate iliac crest, 20 in chin block, and 22 in iliac crest block). Computerized tomographic scans revealed that bone remodeling around apices caused implants to bulge into the sinuses in both particulate bone graft groups. Crestal remodeling around implant necks was similar for all groups., Conclusions: The use of particulate chin bone grafts in sinus lift procedures does not seem to yield optimal outcomes. Milled iliac crest and chin bone tends to remodel around the implant apices, leading to bulging within the sinuses. Grafting sinuses with either chin or.iliac crest bone blocks yields the highest implant success rates and stable sinus floors.
- Published
- 2009
5. Langerhans' cell histiocytosis: a case report of an eosinophilic granuloma of the mandible treated with bone graft surgery and endosseous titanium implants
- Author
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Sbordone, Ludovico, Guidetti, F, MENCHINI FABRIS, G. B., and Sbordone, C.
- Subjects
Dental Implants ,Eosinophilic Granuloma ,Ilium ,Male ,Radiography ,Mandibular Neoplasms ,bone grafting ,langgerhans' cell histiocytosis ,Bone Transplantation ,dental implants ,eosinophilic granuloma ,Dental Implantation, Endosseous ,Humans ,Middle Aged - Abstract
Eosinophilic granuloma is the localized and most benign form of Langerhans' cell histiocytosis. The disease shows a particular predilection for the head and neck region and usually involves the skull bones, where it manifests as well-defined lytic lesions on standard radiographs. The case of an extensive lesion involving the body of the mandible in a 52-year-old man is reported. Operative procedures consisted of enucleation of the lytic lesion and follow-up with clinical examinations and computerized tomographic studies of the mandible at 2, 12, and 18 months postoperatively. Reconstructive surgery without radiotherapy was performed with an autologous bone graft from the iliac crest and implant placement to provide support for a dental restoration.
- Published
- 2006
6. Sinus En Bloc Inlay Grafting With Lateral Approach and Bone Lid Replacement: Report of a Series of Cases
- Author
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Carolina Sbordone, Paolo Toti, Ludovico Sbordone, Luigi Califano, GiovanBattista Menchini-Fabris, Franco Guidetti, Sbordone, L., Sbordone, C., Toti, P., Menchini Fabris, G., Califano, Luigi, and Guidetti, F.
- Subjects
Adult ,Male ,medicine.medical_specialty ,sinusitis ,Grafting (decision trees) ,Alveolar Bone Loss ,Sinus lift ,bone lid repositioning ,autologous grafting ,functional endoscopic surgery ,Dentistry ,bone ,medicine ,Humans ,Sinusitis ,Sinus (anatomy) ,Bone Transplantation ,Inlay ,business.industry ,Maxillary Sinus ,Middle Aged ,medicine.disease ,Autologous grafting ,Surgery ,Dental Implantation ,medicine.anatomical_structure ,Otorhinolaryngology ,graft ,Female ,Oral Surgery ,business ,Lateral approach - Published
- 2010
7. Clinical survey of neurosensory side-effects of mandibular parasymphyseal bone harvesting
- Author
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Ludovico Sbordone, Paolo Toti, Franco Guidetti, Carolina Sbordone, GiovanBattista Menchini-Fabris, Luigi Califano, Sbordone, L., Menchini Fabris, G. B., Toti, P., Sbordone, C., Califano, Luigi, and Guidetti, F.
- Subjects
Adult ,Male ,Chin ,Cuspid ,medicine.medical_treatment ,Lower lip ,Dentistry ,chin bone graft ,mandibular parasymphyseal bone harvesting ,pulp sensitivity loss ,hypoaesthesia ,hypoalgesia ,Skin sensitivity ,Osteotomy ,Transplantation, Autologous ,bone ,Statistics, Nonparametric ,Hypesthesia ,mandible ,Mental foramen ,Postoperative Complications ,stomatognathic system ,Humans ,Medicine ,Longitudinal Studies ,Cranial Nerve Injuries ,Dental Pulp ,chin bone graft, mandibular parasymphyseal bone harvesting, pulp sensitivity loss, hypoaesthesia, hypoalgesia ,Bone Transplantation ,Chi-Square Distribution ,Hypoalgesia ,business.industry ,Mandibular teeth ,Middle Aged ,harvesting ,stomatognathic diseases ,medicine.anatomical_structure ,Otorhinolaryngology ,Tissue and Organ Harvesting ,Pulp (tooth) ,Female ,Trigeminal Nerve Injuries ,Surgery ,Oral Surgery ,business - Abstract
The aim of the present survey was to assess neurosensory disturbances and/or tooth-pulp sensitivity losses after mandibular parasymphyseal bone-harvesting procedures. Twenty-eight harvesting areas in 16 patients were surveyed. Mucosal and skin sensitivity of the chin/lower lip, divided into four regions, were determined via Pointed-Blunt and Two-Point-Discrimination Tests. Pulp sensitivity of the mandibular teeth from the left second bicuspid to the right second bicuspid was tested by cold vitality preoperatively and 12 months postoperatively. Teeth were grouped according to sensitivity alterations and distance from the harvesting defects, as measured on CT scans, and statistically significant differences sought. At 12 months, 29% of preoperatively vital cuspids overlying the harvesting defects revealed pulp-sensitivity losses; no patient reported anaesthesia or analgesia; hypoaesthesia was present in 4% (8 sites; 2 patients), hypoalgesia was present in 3% (5 sites; 2 patients) and Two-Point-Discrimination Tests yielded pathologic responses in 5% of tested areas (10 sites; 4 patients). Teeth with and without pulp sensitivity changes were statistically indistinguishable regarding distances between root apices or mental foramen and the harvesting defect. The loss of pulp sensitivity in any tooth cannot be predicted simply on the basis of the distance between its apex and the harvesting osteotomy line.
- Published
- 2009
8. Gene clustering analysis in human osseous remodeling
- Author
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Marco Baldoni, Natalia Filice, GiovanBattista Menchini-Fabris, Carolina Sbordone, Paolo Toti, Ludovico Sbordone, Sbordone, L, Sbordone, C, Filice, N, MENCHINI-FABRIS, G, Baldoni, M, and Toti, P
- Subjects
Vascular Endothelial Growth Factor A ,Pathology ,medicine.medical_specialty ,Bone Regeneration ,Proto-Oncogene Proteins c-jun ,Gene clustering analysis in human osseous remodeling ,Interleukin-1beta ,Osteogenesis, Distraction ,Genomics ,Core Binding Factor Alpha 1 Subunit ,Computational biology ,Biology ,Bone remodeling ,Gene interaction ,Osteogenesis ,genomics ,medicine ,Data Mining ,Humans ,Alveolar ridge augmentation ,Bone Resorption ,Bone regeneration ,Cluster analysis ,Gene ,Alveolar ridge augmentation, bone remodeling, bone resorption,computational biology, genomics, endosseous dental implantation ,Bone Transplantation ,Guided Tissue Regeneration ,Interleukin-6 ,Tumor Necrosis Factor-alpha ,Computational Biology ,endosseous dental implantation ,Cell cycle ,Transcription Factor AP-1 ,Multigene Family ,Periodontics ,Iterative search ,Bone Remodeling ,Proto-Oncogene Proteins c-fos ,Algorithms ,Forecasting - Abstract
Background: Tentative bioinformatic predictions were performed to comprehend the complexity of the gene interaction networks of the T lymphocyte cell cycle and of human periodontitis. This study aims to identify and rank genes involved in osseous augmentation or bone remodeling to obtain groups with more numerous predicted associations called the leader gene clusters. Methods: An iterative search (consisting of a consecutive expansion-filtering loop) was performed for which only genes involved in a specific process were identified. For each gene, predicted associations with all other involved genes were obtained from a Web-available database (Search Tool for the Retrieval of Interacting Genes/Proteins) and the weighted number of links (WNL), given by the sum of only high-confidence predicted associations (results with a score 0.9), allowing gene ranking. Genes belonging to higher clustering classes were identified. Results: A total of 161 genes potentially involved in bone-volume augmentation and 128 genes connected with the bone-remodeling phenomenon were identified. For the bone-volume augmentation process, only one gene belonged to the leader gene group, whereas six other genes were classified as cluster B genes; for the bone-remodeling phenomenon, three leader genes were identified, whereas six other genes formed the cluster B group. No one gene belonged to leader gene clusters of both processes,whereas one gene of each higher cluster group belonged to the immediately lower cluster of the opposite process. Only three genes of the higher clusters were experimentally involved in both analyses. Conclusions: A de novo identification was performed based on the data mining of leader genes involved in bone-volume augmentation or bone remodeling to acquire primeval information about their molecular basis and to plan future ad hoc targeted experiments. For several genes of the upper clusters, an active role in the bone processes was already known, but the present analysis suggested that they play a major role in the analyzed phenomena. The role of the transcription factors as leader genes and the numerous orphan genes (genes with WNL = 0) recovered probably attest to a lack of information regarding these processes, which could be further clarified through specific DNA microarray experiments. J Periodontol 2009;80:1998-2009.
- Published
- 2009
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