4 results on '"Alba Lucilvânia Fonseca Chaves"'
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2. CARACTERIZAÇÃO HISTOQUÍMICA DE ÓRGÃOS VEGETATIVOS DE LANTANA CAMARA L. (VERBENACEAE) OCORRENTE NO SUL DA BAHIA/ HISTOCHEMICAL CHARACTERIZATION OF LANTANA CAMARA L VEGETATIVE ORGANS. (VERBENACEAE) OCCURRING IN SOUTHERN BAHIA
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Jerônimo Pereira de França, Lucimar Pereira de França, Aline Oliveira da Conceição, Alba Lucilvânia Fonseca Chaves, and Júlia Santos Pinto de Sousa
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Marketing ,Pharmacology ,Organizational Behavior and Human Resource Management ,biology ,Strategy and Management ,Verbenaceae ,Drug Discovery ,Lantana camara ,Botany ,Pharmaceutical Science ,biology.organism_classification - Abstract
Lantana camara L. (Verbenaceae) e uma planta de caule lenhoso, ramos eretos e com inflorescencia com bractea-involucrais externas, flor com calice menor que 2.5/4.5 lobado, corola amarela/vermelha/laranja maior que as bracteas e o fruto e da cor vinacea com mesocarpo do tipo carnoso de ocorrencia mundial. Esta especie se adapta facilmente em regioes com acao antropica. Na familia, L. camara e uma das mais estudadas no mundo como planta medicinal, entretanto, raros sao os estudos histoquimicos envolvendo partes vegetativas desta especie. O estudo teve como objetivo identificar e localizar in situ metabolitos presentes nas folhas de L. camara ocorrente em area de Mata Atlântica, no sul da Bahia, Brasil. Cortes realizados a mao livre em folhas frescas e fixadas em formalina neutra tamponada de especimes coletados na localidade de Marau, Bahia, Brasil foram submetidas a histoquimica e observacao microscopica. Alcaloides foram identificados em tricomas glandulares e nos idioblastos; lipideos em tricomas glandulares, no parenquima palicadico e na cuticula; lignina, nas celulas do xilema; compostos fenolicos no parenquima palicadico, nos tricomas glandulares e oleos essenciais nas celulas do xilema, do floema e no feixe vascular. Os resultados deste trabalho corroboraram estudos anteriores e agregaram conhecimento com a descricao da presenca de alcaloides, ainda nao descritos nas folhas de L. camara por metodo histoquimico que possibilitarao direcionamento para pesquisas futuras sobre o uso da planta. more...
- Published
- 2020
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3. Evaluation of antitumoral and antimicrobial activity of Morinda lcitrifolia L. grown in Southeast Brazil
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Silvana Gaiba, Thamyris Candida, Célio Kersul do Sacramento, Lucimar Pereira de França, Fernanda Andrade Rodrigues Lopes, Alba Lucilvânia Fonseca Chaves, Lydia Masako Ferreira, Jerônimo Pereira de França, Univ Estadual Santa Cruz UESC, Univ Estadual Santa Cruz, Universidade Federal de São Paulo (UNIFESP), 1A CNPq, and Med III CAPES more...
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Staphylococcus aureus ,Time Factors ,Morinda citrifolia L ,RD1-811 ,Cell Survival ,Drug Screening Assays Antitumor ,Enzyme-Linked Immunosorbent Assay ,Microbial Sensitivity Tests ,medicine.disease_cause ,Mice ,Minimum inhibitory concentration ,Anti-Infective Agents ,Cell Line, Tumor ,Botany ,Escherichia coli ,medicine ,Animals ,Viability assay ,Morinda ,Melanoma ,Analysis of Variance ,Ethanol ,biology ,Traditional medicine ,Plant Extracts ,Reproducibility of Results ,biology.organism_classification ,Antimicrobial ,Antineoplastic Agents, Phytogenic ,Fruit ,Surgery ,Drug Screening Assays, Antitumor ,Antibacterial activity ,Staphylococcus ,Brazil - Abstract
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Bahia Research Foundation (FAPESB) PURPOSE: To evaluate the antitumor and antimicrobial activity of ethanolic extract of Morinda citrifolia L. fruit cultivated in southeastern Brazil.METHODS: Preparation ethanolic extract of the fruit of Morinda citrifolia L. Culture of melanoma cells B16-F10 for treatment with ethanolic extract of Morinda citrifolia L. fruit to determine cell viability by MTT and determination temporal effect of ethanolic extract fruit on the cell growth B16-F10 for 8 days. Evaluation of antimicrobial activity of ethanolic extract fruit against Staphylococcus aureus and Escherichia coli by determination of Minimum Inhibitory Concentration (MIC).RESULTS: the ethanolic extract of Morinda citrifolia L. fruit (10mg/mL) decreased cellular activity and inhibited 45% the rate of cell proliferation of B16-F10 melanoma treated during period studied. the ethanolic extract of Morinda citrifolia L. fruit demonstrated antimicrobial activity inhibiting the growth of both microorganisms studied. Staphylococcus aureus was less resistant to ethanolic extract of Morinda citrifolia L. fruit than Escherichia coli, 1 mg/mL and 10 mg/mL, respectively.CONCLUSION: What these results indicate that the ethanolic extract of the fruit of Morinda citrifolia L. showed antitumor activity with inhibition of viability and growth of B16-F10 cells and also showed antibacterial activity as induced inhibition of growth of Staphylococcus aureus and Escherichia coli. Univ Estadual Santa Cruz UESC, Dept Ciencias Biol, BR-45662900 Ilheus, BA, Brazil Univ Estadual Santa Cruz, Dept Agr & Environm Sci, BR-45662900 Ilheus, BA, Brazil Universidade Federal de São Paulo, Div Plast Surg, São Paulo, Brazil 1A CNPq, São Paulo, Brazil Med III CAPES, São Paulo, Brazil Universidade Federal de São Paulo, Div Plast Surg, São Paulo, Brazil Web of Science more...
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- 2014
4. Evaluation of antimicrobial and antitumoral activity of Garcinia mangostana L. (mangosteen) grown in Southeast Brazil
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Bruna Lais Almeida Cunha, Célio Kersul do Sacramento, Renato Fontana, Lydia Masako Ferreira, Jerônimo Pereira de França, Lucimar Pereira de França, Silvana Gaiba, Alba Lucilvânia Fonseca Chaves, Andrea Aparecida de Fátima Souza Moraes, Universidade Estadual de Santa Cruz Department of Biological Sciences, Universidade Estadual de Santa Cruz Departament of Agricultural and Environmental Sciences, and Universidade Federal de São Paulo (UNIFESP) more...
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Staphylococcus aureus ,food.ingredient ,Time Factors ,RD1-811 ,Cell Survival ,Enzyme-Linked Immunosorbent Assay ,Microbial Sensitivity Tests ,Biology ,medicine.disease_cause ,Garcinia mangostana L ,Garcinia mangostana ,Minimum inhibitory concentration ,Mice ,food ,Anti-Infective Agents ,Cell Line, Tumor ,Botany ,medicine ,Animals ,Agar diffusion test ,Viability assay ,Fragmentation (cell biology) ,Melanoma ,Traditional medicine ,Plant Extracts ,Reproducibility of Results ,food and beverages ,Antimicrobial ,Antineoplastic Agents, Phytogenic ,Comet assay ,Fruit ,Surgery ,Comet Assay ,Drug Screening Assays, Antitumor ,Genotoxicity ,Brazil - Abstract
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Bahia Research Foundation (FAPESB) PURPOSE:To characterize the anatomy of the fruit and leaf and the presence of phytocompounds. To evaluate the antitumor and antimicrobial activity of ethanolic extract of Garcinia mangostana L. (mangosteen) cultivated in southeastern Brazil.METHODS:Anatomical characterization and histochemical reactions were performed for structural identification and the presence of phytocompounds. Preparation of ethanolic extract of the fruit, leaf and resin of mangosteen. Culture B16-F10 melanoma cells for treatment with mangosteen ethanolic extract to determine cell viability by MTT and genotoxic effect by comet assay. Evaluation by antimicrobial activity against Staphylococcus aureus and Escherichia coli by agar diffusion test and by determination of Minimum Inhibitory Concentration (MIC).RESULTS:Our results showed many secretory canals in resin fruit and leaf; identifying lipids, starch, lignin and phenolic compounds. The leaf extract induced genotoxicity and apoptosis in B16-F10 cells, since the fragmentation of DNA in the comet assay. The ethanolic extract of mangosteen obtained in the resin, leaf and fruit showed antimicrobial activity against Staphylococcus aureus and Escherichia coli with a MIC at 0.1 mg/mL.CONCLUSION: In conclusion, we have demonstrated both antimicrobial and antitumor activity of ethanol extract of mangosteen emphasizing its therapeutic potential in infectious diseases and in cancer, such as melanoma. Universidade Estadual de Santa Cruz Department of Biological Sciences Universidade Estadual de Santa Cruz Departament of Agricultural and Environmental Sciences UNIFESP UNIFESP SciELO more...
- Published
- 2014
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