1. Profile and 1-Year Outcome of Ischemic Stroke in East China: Nanjing First Hospital Stroke Registry.
- Author
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Shi GM, Zhang YD, Geng C, Zhang YQ, Pan XD, Liu YK, Yang J, and Zhou JS
- Subjects
- Aged, Brain Damage, Chronic etiology, Brain Ischemia complications, Brain Ischemia therapy, China epidemiology, Comorbidity, Diabetes Mellitus epidemiology, Female, Follow-Up Studies, Gastrointestinal Hemorrhage epidemiology, Heart Diseases epidemiology, Hospitals, Public statistics & numerical data, Humans, Hyperlipidemias epidemiology, Kidney Diseases epidemiology, Male, Middle Aged, Pneumonia epidemiology, Recurrence, Registries, Risk Factors, Sex Factors, Survival Analysis, Treatment Outcome, Brain Damage, Chronic epidemiology, Brain Ischemia epidemiology
- Abstract
Background: The profile and 1-year outcome after acute ischemic stroke (AIS) in Nanjing, China, is uncertain. This study aimed to investigate the profile and outcome after 1-year follow-up of AIS in East China., Methods: In a prospective cohort study, 2168 patients with AIS were recruited consecutively. The primary outcome was death or dependency defined as a modified Rankin Scale score of 3-6 at 12 months. Plausible risk factors of death or dependency, such as demographics, risk factors of cardiovascular diseases, clinical features, laboratory results, and complications after a stroke, were selected from available variables to perform multivariable logistic regression analyses., Results: Eight hundred thirty-seven (38.6%) patients died or suffered from dependency. Multivariate logistic regression analysis showed that age (odds ratio [OR], 1.04; 95% confidence interval [CI], 1.03-1.05), history of diabetes mellitus (OR, 1.50; 95% CI, 1.10-2.04), prior stroke (OR, 2.08; 95% CI, 1.51-2.87), National Institutes of Health Stroke Scale (NIHSS) score (OR, 23.06; 95% CI, 14.24-37.34), estimated glomerular filtration rate (OR, 1.65; 95% CI, 1.02-2.66), pulmonary infection (OR, 2.98; 95% CI, 2.17-4.09), and gastrointestinal bleeding (OR, 7.81; 95% CI, 2.76-22.09) were significantly and independently associated with higher rates of mortality or disability (all P values < .05). Male gender (P values < .001) was the only factor associated with lower mortality or disability., Conclusions: The main dominating predictors for death or dependency were older age, female gender, diabetes mellitus, prior stroke, NIHSS score, estimated glomerular filtration rate, pulmonary infection, and gastrointestinal bleeding., (Copyright © 2015 National Stroke Association. Published by Elsevier Inc. All rights reserved.)
- Published
- 2016
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