1. Conjunctival amelanotic melanoma--a case report.
- Author
-
Kovacević D, Lukanović-Primc K, Markusić V, Babić MB, and Ledić D
- Subjects
- Aged, 80 and over, Biomarkers, Tumor metabolism, Biopsy, Brain Neoplasms diagnostic imaging, Brain Neoplasms metabolism, Conjunctival Neoplasms metabolism, Female, Humans, MART-1 Antigen metabolism, Melanoma, Amelanotic diagnostic imaging, Melanoma, Amelanotic metabolism, S100 Proteins metabolism, Tomography, X-Ray Computed, Brain Neoplasms secondary, Conjunctival Neoplasms pathology, Melanoma, Amelanotic secondary
- Abstract
Conjunctival melanoma is a relatively rare malignancy. It is presented as pigmented nodule in any area of conjunctiva, amelanotic tumors are pink with smooth appearance. The authors describe an amelanotic melanoma of the conjunctiva in an 82-year-old female patient. Cytological, histopathological and immunohistochemical studies revealed an invasive amelanotic melanoma exhibiting S-100 and MART-1 positivity. The patient undervent surgical and chemotherapy treatment and three years after the initial treatment is in the terminal stage of metastatic disease. Absence of pigmentation delayed early clinical detection and treatment. Awareness of this nonpigmented melanoma is crucial for early recognition and appropriate management.
- Published
- 2011