1. Inhibition of the angiotensin II type 2 receptor AT
- Author
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Richard, Perryman, Alexander, Renziehausen, Hamidreza, Shaye, Androniki D, Kostagianni, Antonis D, Tsiailanis, Thomas, Thorne, Maria V, Chatziathanasiadou, Gregory B, Sivolapenko, Mohamed Ahmed, El Mubarak, Gye Won, Han, Barbara, Zarzycka, Vsevolod, Katritch, Guillaume, Lebon, Cristiana, Lo Nigro, Laura, Lattanzio, Sophie V, Morse, James J, Choi, Kevin, O'Neill, Zoi, Kanaki, Apostolos, Klinakis, Tim, Crook, Vadim, Cherezov, Andreas G, Tzakos, and Nelofer, Syed
- Subjects
Protein Conformation, alpha-Helical ,Analgesics ,Brain Neoplasms ,Angiotensin II ,Drug Repositioning ,Humans ,Apoptosis ,Angiotensin II Type 2 Receptor Blockers ,Benzhydryl Compounds ,Glioblastoma ,Isoquinolines ,Receptor, Angiotensin, Type 2 ,Tumor Burden - Abstract
Glioblastoma (GBM) is an aggressive malignant primary brain tumor with limited therapeutic options. We show that the angiotensin II (AngII) type 2 receptor (AT
- Published
- 2023