1. Clinico-radiological monitoring strategies in patients with metastatic breast cancer: a real-world study
- Author
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Maria Grazia Vitale, Stefania Russo, Valentina Fanotto, Claudia Andreetta, Michele Bartoletti, Debora Basile, Gianpiero Fasola, Marta Bonotto, Fabio Puglisi, Giacomo Pelizzari, Alessandro Marco Minisini, C. Lisanti, Mauro Mansutti, Lorenzo Gerratana, and Elena Poletto
- Subjects
Adult ,Diagnostic Imaging ,Cancer Research ,medicine.medical_specialty ,Clinical Decision-Making ,Breast Neoplasms ,Comorbidity ,Multimodal Imaging ,03 medical and health sciences ,0302 clinical medicine ,Breast cancer ,breast cancer ,Internal medicine ,Biomarkers, Tumor ,Odds Ratio ,polycyclic compounds ,Humans ,Medicine ,030212 general & internal medicine ,Watchful Waiting ,skin and connective tissue diseases ,Aged ,Neoplasm Staging ,Retrospective Studies ,Aged, 80 and over ,determinants of monitoring ,medicine.diagnostic_test ,business.industry ,monitoring breast cancer ,Disease Management ,breast cancer, determinants of monitoring ,metastatic breast cancer ,monitoring strategies ,Magnetic resonance imaging ,Retrospective cohort study ,General Medicine ,Middle Aged ,medicine.disease ,Metastatic breast cancer ,Radiography ,Clinical trial ,Measurable Disease ,Oncology ,030220 oncology & carcinogenesis ,Radiological weapon ,Cohort ,Female ,business - Abstract
Aim: A monitoring strategy for metastatic breast cancer patients (M-MBC) has been little studied. Materials & methods: This retrospective study analyzed a consecutive cohort of 382 MBC patients to analyze different M-MBC strategies to identify factors influencing intensive M-MBC. Results: Elevated baseline serum tumor markers (STM) was the strongest factor associated with increased use of STM tests. Having more frequent oncology office visits was associated with more intensive chemotherapy/magnetic resonance imaging (MRI) using. Increased use of imaging tests was associated with participation to clinical trial. Single and elderly patients were less likely to have frequent testing. Having clinically measurable disease was less likely to have more intensive M-MBC. Conclusion: STM testing and scans were frequently ordered in M-MBC. In the present study, strategies are little influenced by clinico-pathological characteristics.
- Published
- 2020