1. P1-230 Comparison Between Low and Normal Muscle Mass to Quality of Life in Breast Cancer Patients A Preliminary Study.
- Author
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Kurniawan, Andree, Wijovi, Felix, Putri, Helenia, Halim, Devina Adelia, Saroso, Olivia Adji, Kores, Wilson, Rahman, Julang, Dharmaraja, Fernando, and Lugito, Nata Pratama Hardjo
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MUSCLE mass , *BREAST cancer , *BIOELECTRIC impedance , *CANCER patients , *QUALITY of life - Abstract
Background Low muscle mass is one of the prognostic factor that may lead to negative outcome and is the major feature of cancer cachexia, including breast cancer. Sarcopenia is associated with reduced quality of life (QoL) and survival. There is limited data reported about this association. The aim of this study is to know the comparison between low muscle mass and Quality of Life in Indonesian Breast Cancer Patients. Methods The data was collected using cross-sectional Method from October 2018- February 2019. Patients who had breast cancer and have underwent chemotherapy are included in this study and evaluated using BR-23 questionnaire, and Bioelectric Impedance Analysis (BIA) to assess their muscle mass with the cut-off of 5.7 kg/m2. the comparison between both lower muscle mass and higher muscle mass to QoL are evaluated using t-test in SPSS version 24.0. Result From 36 patients with mean age 48.28 +- 9.8 , median muscle mass is 5.92 ranged from 4.48 to 8.32. Patient with low muscle mass had functional mean of QoL 54.55% +-8.45 and symptoms mean of QoL 85.34% +- 3.09. while Patient with normal muscle mass had functional mean of QoL 56.02% +-8.8 and symptoms mean of QoL 86.51+-12.05. The Association between muscle mass and QoL is defined as p-value of 0.658. Conclusion Patients with low muscle mass have lower QoL, whereas patient with high muscle mass have better QoL. However, muscle mass association to quality of life is still unclear. Thus, further study with greater sample is needed to confirm the result [ABSTRACT FROM AUTHOR]
- Published
- 2019
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