1. A Review of Traditional Chinese Medicine for Triple Negative Breast Cancer and the Pharmacological Mechanisms.
- Author
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Wu, Qinhang, Yan, Hongkai, and Kang, Ziyi
- Subjects
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BREAST tumor treatment , *CHINESE medicine , *CANCER invasiveness , *DETOXIFICATION (Alternative medicine) , *HOMEOSTASIS , *DRUG resistance in cancer cells , *MEDICAL prescriptions , *BREAST tumors , *HERBAL medicine , *MICRORNA , *CELL physiology , *PHILOSOPHY of medicine , *DIURETICS , *CELLULAR signal transduction , *QUALITY of life , *ONCOGENES , *BLOOD circulation , *PAIN management , *DRUG synergism , *TUMOR necrosis factors , *THERAPEUTICS - Abstract
Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer. Conventional treatment options for TNBC often have limited efficacy and significant side effects. In recent years, traditional Chinese medicine (TCM) has shown promising results in the treatment of TNBC. TCMs include herb combinations that have synergistic effects to regulate homeostasis in the body, reduce tumor resistance, and improve patient quality of life. At present, three main TCM methods are used to treat TNBC in the clinic: strengthening the body's resistance, dispelling phlegm, and removing cancer toxins. This paper reviews the theories and mechanisms of each in TNBC treatment. The method of strengthening the body's resistance emphasizes enhancing the body's original Qi to fight against pathogenic factors; the method of dispelling phlegm seeks to eliminate phlegm stagnation and alleviate the burden on affected organs; the method of removing cancer toxins focuses on detoxification and detumescence to remove the toxic elements associated with TNBC. Although these methods treat TNBC from different etiologies, they have achieved good therapeutic effects and represent an important academic approach: That is, to cure the disease with a comprehensive view of the body and restore the balance of Yin and Yang. This knowledge lays a foundation for the future development and reasonable application of TCM in the clinic. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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