1. Effects of vaccination with Brucella melitensis, strains Rev 1 ΔeryCD and Rev 1, on the reproductive system of young male goats.
- Author
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López Vásquez IA, Palomares Resendiz EG, Gutiérrez Hernández JL, Garrido Fariña GI, Tórtora Pérez JL, de Jesús Olmos Espejel J, Hernández Castro R, Sangari F, Suárez Güemes F, and Díaz Aparicio E
- Subjects
- Animals, Male, Vaccination, Genitalia, Male microbiology, Bacterial Vaccines, Goats, Brucella melitensis immunology, Brucellosis prevention & control, Brucellosis veterinary, Brucellosis microbiology, Brucella Vaccine immunology, Brucella Vaccine administration & dosage
- Abstract
The present study evaluates the effects of vaccination with Brucella melitensis strains Rev 1 ΔeryCD and Rev 1 on the reproductive system of male goats. Three groups, each of them consisting of 15 six-month-old brucellosis-free male goats, were studied. The first group was vaccinated with the Rev 1 ΔeryCD strain, the second group received Rev 1 and the third group was inoculated with sterile physiological saline solution. The dose of both strains was of 1×10
9 CFU/ml. Over the course of the five months of this study, three males from each group were euthanized every month. Their reproductive tracts, spleens, and lymph nodes were collected to analyze serology, bacteriology PCR, histology, and immunohistochemistry. Results show that vaccination with B. melitensis strains Rev 1 ΔeryCD and Rev 1 does not harm the reproductive system of male goats. Strain B. melitensis Rev 1 ΔeryCD displayed a lower capacity to colonize the reproductive tract than strain Rev 1, which was attributed to its limited catabolic action toward erythritol., (Copyright © 2024 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.)- Published
- 2024
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