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1. Investigation and implementation of 8D methodology in a manufacturing system

Author: Saeedur Rahman, Rajeev Rathi, Annam Lakshmi Narayana, Maddireddy Chandra Gopi Reddy, and Utlapalli Lakshmi Narayana
Subjects: Product (business), Quality management, Work (electrical), Sustainability, Revenue, Time management, Business, Business model, Root cause analysis, Manufacturing engineering
Abstract: The micro, small, and medium-sized business (MSMEs) industry is the economy's growth engine. Micro-Small and Medium Enterprises have a greater Labour strength than large businesses. Micro-Small and Medium Enterprises account for most jobs in any sector. Waste reduction, quality improvement, time management, environmental sustainability, and growth measures are all major issues for Micro-Small and Medium Enterprises. As a result, any business needs a good team and a long-term business model to succeed. One of the most reliable designs for product and quality development, waste reduction, and problem-solving is the 8Ds methodology. As a result, the goal of this 8Ds methodology is to adopt and investigate a simple sustainable work method that aids in the reduction of time decay and waste. Micro-Small and Medium Enterprises have a high rate of manufacturing defects, which leads to company failure and a decline in sales and revenue. The 8Ds work method entails forming a proactive team to tackle these questions. The primary goal of this research paper is to identify a problem with both the gearbox and vibrator in the well-known tobacco industry and to use the Eight Disciplines(8D) methodology to minimize breakdown time and repair costs of the machinery. All these details were gathered from various industrial processes to research and evaluate the 8d methodology. The 8d approach, root cause analysis, and fishbone diagram were also used to solve the problem described above. After changing the gear material and using lubricants between the gear and the vibrator, the breakdown time was reduced. Following a successful implementation of the changes, the break manufacturing time of the tobacco bundle was reduced by 29 percentage and defects were reduced by 72 percentage as well as the equipment cost of maintenance.
Published: 2022
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2. REAL TIME OBJECT DETECTION USING YOLO ALGORITHM

Author: Palli R Krishna Prasad, Annam Subbarao, Dammati Vidya Sri, Gadidammalla Narendra Kumar, and Bobburi Taralathasri
Subjects: business.industry, Computer science, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, Computer vision, Artificial intelligence, business, Object detection
Abstract: The major and wide range applications like Driverless cars, robots, Image surveillance has become famous in the Computer vision .Computer vision is the core in all those applications which is responsible for the image detection and it became more popular worldwide. Object Detection System using Deep Learning Technique” detects objects efficiently based on YOLO algorithm and applies the algorithm on image data to detect objects.
Published: 2021
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3. Mechanisms underlying the therapeutic potential of mesenchymal stem cells in atherosclerosis

Author: Brian Wang, Ravi Amin, Thomas Kirwin, Sahil Goswami, Annam Sufi, and Ana R. Gomes
Subjects: Vascular wall, 0303 health sciences, Embryology, business.industry, Mesenchymal stem cell, Biomedical Engineering, Cell Differentiation, Mesenchymal Stem Cells, Inflammation, Disease, Atherosclerosis, Mesenchymal Stem Cell Transplantation, Immunomodulation, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, medicine, Cancer research, Humans, Identification (biology), medicine.symptom, Stem cell, business, 030304 developmental biology
Abstract: Atherosclerosis is a chronic inflammatory condition resulting in the formation of fibrofatty plaques within the intimal layer of arterial walls. The identification of resident stem cells in the vascular wall has led to significant investigation into their contributions to health and disease, as well as their therapeutic potential. Of these, mesenchymal stem cells (MSCs) are the most widely studied in human clinical trials, which have demonstrated a modulatory role in vascular physiology and disease. This review highlights the most recent knowledge surrounding the cell biology of MSCs, including their origin, identification markers and differentiation potential. The limitations concerning the implementation of MSC therapy are considered and novel solutions to overcome these are proposed.
Published: 2021
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4. Guidelines for expert testimony in pediatric radiology

Author: Michael J. Callahan, Diego Jaramillo, Taylor Chung, R. Paul Guillerman, Peter J. Strouse, Aparna Annam, and Stephen D. Brown
Subjects: Medical education, business.industry, media_common.quotation_subject, education, Ethics committee, humanities, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, Pediatric Radiology, 0302 clinical medicine, Expert witness, Legal testimony, 030225 pediatrics, Pediatrics, Perinatology and Child Health, Medical imaging, Medicine, Radiology, Nuclear Medicine and imaging, business, Duty, health care economics and organizations, Neuroradiology, media_common
Abstract: Pediatric radiologists have the professional and ethical duty to assist, inform and educate the legal system in regard to matters involving medical imaging in children. These guidelines, drafted by the Society for Pediatric Radiology Ethics Committee and approved by the Society for Pediatric Radiology Board of Directors, provide recommendations for expert legal testimony in pediatric radiology and codify minimal ethical norms for the pediatric radiology expert witness in legal proceedings.
Published: 2021
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5. Dental Aesthetic Index (Dai) Score Among Patients with Antero-Posterior Basal Bone Discrepancy

Author: Annam imtiaz, Usman Yousaf, Mohammad Umar Shah, Muhammad Afzal, Aaqil Malik, and Ch. Rehan Qamar
Subjects: Basal (phylogenetics), Index (economics), business.industry, Medicine, Anatomy, business
Abstract: Aim: To determine the mean Dental Aesthetic Index (DAI) malocclusion score among patients with Antero-posterior basal bone discrepancy (APBBD) and to assess the treatment need of the patients with horizontal jaw deformities as calculated by DAI guidelines. Methodology: The descriptive cross sectional study was conducted in the Orthodontic department, University College of Dentistry, The University of Lahore. Lateral cephalograms of the patients were analyzed for anteroposterior basal bone discrepancy by measuring angle ANB. Two hundred and thirty one subjects were included in the study having ANB >4° or
Published: 2021
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6. Analysis of NOMA-OFDM 5G wireless system using deep neural network

Author: Ravi Shankar, Manoj Ashok Wakchaure, Jagadeeswara Rao Annam, and Sharnil Pandya
Subjects: Artificial neural network, business.industry, Orthogonal frequency-division multiplexing, Computer science, Real-time computing, 020206 networking & telecommunications, 02 engineering and technology, medicine.disease, Noma, Signal-to-noise ratio, Modeling and Simulation, 0202 electrical engineering, electronic engineering, information engineering, medicine, Wireless, 020201 artificial intelligence & image processing, business, Engineering (miscellaneous), 5G, Decoding methods, Computer Science::Information Theory, Communication channel
Abstract: In this work, a multiple user deep neural network-based non-orthogonal multiple access (NOMA) receiver is investigated considering channel estimation error. The decoding of the symbol in the case of the NOMA system follows the sequential order and decoding accuracy depends on the detection of the previous user. Without estimating the throughput, a deep neural network-based NOMA orthogonal frequency division multiplexing (OFDM) system is proposed to decode the symbols from the users. Firstly, the deep neural network is trained. Secondly, the data are trained and lastly, the data are tested for various users. In this work, for various values of signal to noise ratio, the performance of the deep neural network is investigated, and the bit error rate (BER) is calculated on a per subcarrier basis. The simulation results show that the deep neural network is more robust to symbol distortion due to inter-symbol information and will obtain knowledge of the channel state information using data testing.
Published: 2021
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7. Society of Interventional Radiology Quality Improvement Standards for Percutaneous Nephrostomy in the Pediatric Population

Author: Richard B. Towbin, Harry R. Cramer, Kevin M. Baskin, John J. Crowley, Drew M. Caplin, Anne Marie Cahill, Waleska M. Pabon-Ramos, Aparna Annam, Hasmukh J. Prajapati, Elizabeth A. Himes, Sandeep Vaidya, Manraj K.S. Heran, Giridhar M. Shivaram, Mark J. Hogan, Shellie Josephs, and Bairbre Connolly
Subjects: Urologic Diseases, medicine.medical_specialty, Consensus, Quality management, medicine.medical_treatment, MEDLINE, Radiology, Interventional, Radiography, Interventional, Pediatrics, medicine, Humans, Radiology, Nuclear Medicine and imaging, Child, Nephrostomy, Percutaneous, Quality Indicators, Health Care, medicine.diagnostic_test, business.industry, General surgery, Infant, Newborn, Infant, Interventional radiology, Quality Improvement, Percutaneous nephrostomy, Child, Preschool, Urinary Catheterization, Cardiology and Cardiovascular Medicine, business, Pediatric population
Published: 2021
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8. Society of Interventional Radiology Quality Improvement Standards for Percutaneous Cholecystostomy and Percutaneous Transhepatic Biliary Interventions

Author: Alda L. Tam, Aparna Annam, Andrew J. Gunn, Sheena Patel, Lynn A. Brody, Elizabeth A. Himes, A. Michael Devane, and Sean R. Dariushnia
Subjects: medicine.medical_specialty, Consensus, Quality management, Percutaneous, medicine.diagnostic_test, business.industry, General surgery, Treatment outcome, Psychological intervention, MEDLINE, Interventional radiology, Radiology, Interventional, Quality Improvement, Biliary Tract Surgical Procedures, Treatment Outcome, Risk Factors, Humans, Medicine, Percutaneous cholecystostomy, Radiology, Nuclear Medicine and imaging, Patient Safety, Cardiology and Cardiovascular Medicine, business, Cholecystostomy, Quality Indicators, Health Care
Published: 2020
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9. Primary Transitional Cell Carcinoma of Fallopian Tube: A Rare Entity with Review of Literature

Author: Arun Elangovan, Vani Bharani, Chinna Babu Dracham, and Lokeswari Annam
Subjects: Pathology, medicine.medical_specialty, Transitional cell carcinoma, medicine.anatomical_structure, business.industry, Rare entity, medicine, business, medicine.disease, Fallopian tube
Abstract: Objective: Primary fallopian tube carcinoma (PFTC) is a rare entity constituting only 0.2-1.5% of all primary female genital-tract malignancies. Transitional cell carcinoma of fallopian tube is very rare constituting only around 10% of the PFTC and very less literature have been reported worldwide. Case report: A 59-year-old postmenopausal women presented with discharge per vaginum and abdominal distension, and was found to have right adnexal mass on clinical examination. Imaging findings were suggestive of a heterogenous adnexal mass and she underwent staging laparotomy. Post-operative histopathology examination confirmed a primary transitional cell carcinoma of right fallopian tube. FIGO stage was IA, and she received six cycles of adjuvant chemotherapy. The patientis nowalive, after 10-years of initial treatment.
Published: 2020
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10. Classification of ECG Heartbeat Arrhythmia: A Review

Author: Srinivas Kalyanapu, Jagadeeswara Rao Annam, Sureshbabu Ch., Jayaprada Somala, and S. Bapi Raju
Subjects: Heartbeat, business.industry, Computer science, 020206 networking & telecommunications, 02 engineering and technology, Machine learning, computer.software_genre, 0202 electrical engineering, electronic engineering, information engineering, General Earth and Planetary Sciences, 020201 artificial intelligence & image processing, Artificial intelligence, business, computer, General Environmental Science
Abstract: Manual identification of ECG heart-beat classes by cardiologists is time consuming and cumbersome. These professionals rely on computer based methods for determination of these heart-disease types. In this work, existing literature is organized into a proposed taxonomy based on dichotomies involving full time series-based versus feature-based, AAMI versus Non-AAMI, and inter-patient versus intra-patient based distinctions. The basic contributions of this work are systematic review of literature on heart-beat abnormality detection, identifying research gaps and the research issues unmet sofar in the literature to propose novel approaches for addressing these gaps.
Published: 2020
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11. ECONOMIC BURDEN OF DIABETES IN TELANGANA: A COST OF ILLNESS STUDY

Author: Hemanth kumar Annam, Harika Gorla, and Priyanka Nomula
Subjects: medicine.medical_specialty, business.industry, Type 2 Diabetes Mellitus, Disease, medicine.disease, Nephropathy, Indirect costs, Heart failure, Diabetes mellitus, Emergency medicine, medicine, Myocardial infarction, business, health care economics and organizations, Retinopathy
Abstract: The purpose of this study is to analyze the economic burden on people in Telangana due to diabetes. In Telangana, a prospective observational study was conducted by collecting patient data. 252 patient’s data was gathered in 6 months period. This data includes health care costs and complications that is both microvascular complications (Neuropathy, Retinopathy & Nephropathy) and macrovascular complications (Coronary heart disease, Congestive heart failure, Myocardial infarction & Peripheral artery disease). The collected data consists of direct and indirect costs which was analyzed & calculated average cost spent in the treatment of diabetic patients. All the type 2 diabetes mellitus patients who are on anti – diabetic drugs irrespective of their co- morbidities & gender were included. Patients who are not on regular medication were excluded from the study. In this study , cost of illness of type-2 diabetes mellitus patients with & without complications were compared. The total cost of treatment per annum in patients without complications was USD 374.77 & in patients with complications was USD 497.763.
Published: 2020
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12. Effect of artesunate and amodiaquine alone and in combination on plasma biochemical parameters in mice

Author: VB Annam, EK Armah, BB Boamah, and James Abugri
Subjects: chemistry.chemical_compound, chemistry, Artesunate, business.industry, medicine, Amodiaquine, Pharmacology, business, medicine.drug
Published: 2021
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13. ECG Feature Extraction

Author: Bapi Raju Surampudi, R. Sujatha, Gutta V. S. N. R. V. Prasad, Narayana Satyala, Jagadeeswara Rao Annam, and Jayaprada Somala
Subjects: ECG feature, business.industry, Computer science, Extraction (chemistry), Pattern recognition, Artificial intelligence, business
Published: 2021
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14. Extracorporeal membrane oxygenation as rescue therapy in a pediatric liver transplant recipient with very severe hepatopulmonary syndrome

Author: Aparna Annam, Joy Huang, Todd C. Carpenter, Sheila Pahlavan, Shikha S. Sundaram, Michael Wachs, Dor Yoeli, and Megan A. Adams
Subjects: Transplantation, Cirrhosis, medicine.diagnostic_test, business.industry, medicine.medical_treatment, Interventional radiology, Liver transplantation, medicine.disease, Hypoxemia, surgical procedures, operative, Anesthesia, Pediatrics, Perinatology and Child Health, Extracorporeal membrane oxygenation, medicine, Embolization, Portosystemic shunt, medicine.symptom, Hepatopulmonary syndrome, business
Abstract: BACKGROUND In children with cirrhosis, the prevalence of HPS ranges from 3% to 20%, resulting in impaired gas exchange due to alterations in pulmonary microvasculature. LT is the gold-standard cure for cirrhosis complicated by HPS and should ideally be performed prior to the development of severe HPS due to increased risk for post-transplant hypoxia, right heart failure, and outflow obstruction. METHODS We present a case of a 13-year-old man, who underwent pediatric LT for severe HPS complicated by postoperative respiratory collapse, requiring a 92-day course of veno-venous ECMO. RESULTS Post-transplant, despite BiPAP, inhaled nitric oxide and isoproterenol infusion, he remained hypoxic postoperatively and acutely decompensated on postoperative day 25, requiring veno-venous ECMO. After 84 days on ECMO, a persistent large splenorenal shunt was identified that was embolized by interventional radiology, and 8 days after shunt embolization and ASD closure, he was successfully weaned off ECMO. CONCLUSIONS This case describes the longest known duration of ECMO in a pediatric LT recipient and a unique improvement in hypoxemia following a portosystemic shunt closure. ECMO presents a heroic rescue measure for pediatric LT recipients with HPS that develops acute respiratory failure postoperatively refractory to alternative measures.
Published: 2021
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15. Neonatal Presentation of Congenital Portosystemic Shunt

Author: Rebecca Shay, Clyde J Wright, Lorna P Browne, Shikha S Sundaram, Aparna Annam, and Alyssa Goldberg
Subjects: medicine.medical_specialty, business.industry, Pediatrics, Perinatology and Child Health, MEDLINE, Medicine, Presentation (obstetrics), Portosystemic shunt, business, Article, Surgery
Published: 2021

16. Reversible leukoencephalopathy and cerebral atrophy in homocystinuria due to MTHFR deficiency: A treatable metabolic disorder

Author: Rohan R Mahale, Hansashree Padmanabha, Thuppanattumadam Ananthasubramanian Sangeeth, Pavagada S. Mathuranath, Harikrishna Annam, Ravi Shekhar, Maya Bhat, Rita Christopher, Pooja Mailankody, and Gautham Arunachal
Subjects: Cerebral atrophy, medicine.medical_specialty, Methylenetetrahydrofolate reductase deficiency, business.industry, Metabolic disorder, Homocystinuria, medicine.disease, Gastroenterology, Magnetic Resonance Imaging, White Matter, Leukoencephalopathy, Psychotic Disorders, Leukoencephalopathies, Muscle Spasticity, Internal medicine, Genetics, medicine, Humans, Female, Atrophy, business, Child, Genetics (clinical), Methylenetetrahydrofolate Reductase (NADPH2)
Published: 2021

17. A Topographical Feature Extraction Approach for Classification of Soil Hyperspectral Image

Author: Anshu Singla and Sangeetha Annam
Subjects: Endmember, business.industry, Computer science, Feature extraction, Unsupervised learning, Hyperspectral imaging, Pattern recognition, Artificial intelligence, business, Image resolution, Multispectral pattern recognition, Image (mathematics)
Abstract: Hyperspectral images, having more than hundreds of bands and very high spectral resolution, endeavors a favorable approach for classification of the soil. The accuracy and viability of visible-near infrared (Vis-NIR) hyperspectral imaging proved to be more powerful, as these images have both spatial and spectral information. The purpose of this study is to perform classification on AVIRIS hyperspectral images based on their geographical nature of the soil with endmember selection while comparing various classification models. The classification techniques of these hyperspectral images were analyzed using small fractions among the number of training samples and their spectral features. The study analyzed that use of Constrained Energy Minimization technique yields better results among the various supervised classification techniques. Also, when the hyperspectral data has to be classified using unsupervised learning techniques like K-Means and ISODATA, K-Means performed better than ISODATA with the accuracy of 98.3%.
Published: 2021
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18. User valuation of secrecy Framing based on General Data Protection Regulation (GDPR) users

Author: B Sobhan Babu, Pavan Kumar Ande, Poojitha Tatineni, Chitturi Prasad, Jagadeeswara Rao Annam, and Bhargavi Kanuri
Subjects: Research proposal, Incentive, business.industry, Framing (World Wide Web), General Data Protection Regulation, Internet privacy, Secrecy, media_common.cataloged_instance, The Internet, European union, business, media_common, Valuation (finance)
Abstract: This research paper suggests to build on the results obtained by Goldin and Reck (2020). It suggests to collect a dataset that can be used to test their method. At the same time, the results from the analysis of this dataset will produce framing-consistent estimates of users' privacy setting preferences. The test of Goldin and Reck (2020)'s method will constitute a methodological contribution to the literature on revealed preferences under framing. The preference estimates will contribute to the literature on privacy preferences and will have implications for policy makers concerned with the security concern on personal data present on the internet. It is proposed to write a similar browser add-on to track people's decision about browser cookie settings. According to the General Data Protection Regulation (GDPR) users, who visit a website from within the European Union or the European Economic Area must be asked for their stated consent on storing browser cookies (General Data Protection Regulation 2020). For the intents of this research proposal, one can divide browser cookies into two groups. First, there are essential cookies that are necessary to guarantee the website's functionality. Second, there are third-party ad-tracking cookies. A website's host still has a monetary incentive to nudge users to allow for the ad-tracking cookies. This can be done by choosing the default cookie settings.
Published: 2021
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19. MP62-18 ATENOLOL IS ASSOCIATED WITH REDUCED RISK OF PROSTATE CANCER UPGRADING: A MULTICENTER RETROSPECTIVE STUDY

Author: Emily Wiggins, Kara L. Watts, Evan Garden, Larkin Mohn, Ali H. Zahalka, A. Tewari, Stephen J. Freedland, Lauren E. Howard, Amanda M. DeHoedt, Jay Annam, Ilir Agalliu, Allison L. Reagan, Benjamin Eilender, and Ethan Fram
Subjects: Oncology, medicine.medical_specialty, Prostate cancer, Reduced risk, business.industry, Urology, Internal medicine, medicine, Retrospective cohort study, medicine.disease, business, Atenolol, medicine.drug
Published: 2021
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20. COVID-19 and Mucormycosis: The Double Edge Sword

Author: Annam Prathiba, Kangan Ghadiali, Sheetal Chauhan, Kanav Khera, Ajit Singh, and Siddheesh Rajpurohit
Subjects: medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), business.industry, Double edge, media_common.quotation_subject, Mucormycosis, Disease, medicine.disease, Hygiene, Diabetes mellitus, Health care, Anticipation (genetics), medicine, business, Intensive care medicine, media_common
Abstract: Background and aim India has declared mucormycosis as an epidemic. The incidence rate is rising day by day as there are more than 29000 cases in 28 states until March 2021. COVID-19 is already burdening the health care system, and post-COVID mucormycosis leads to mortality and morbidity in patients treated with COVID-19. This article aims to understand the various complications of mucormycosis and how it is impacting COVID-19 infected patients. Methods A thorough literature search was performed using PubMed, Google Scholar, and Embase from May 2021 to June 2021. The authors selected the articles based on relevance. Mucormycosis, black fungus, fungal infection, COVID-19, pathogenesis, corticosteroids, treatment, antifungals were the major keywords searched. Secondary resources included from the published news articles. Results Through the literature, we observed that patients after COVID-19 are more vulnerable to these fungal infections, especially immunocompromised patients, patients with long-term steroid use, and uncontrolled diabetes. This review enlightens the manifestations, pathogenesis, and various treatment and anticipation policies for mucormycosis. Conclusion Awareness about the possibility of the disease is necessary to reduce the delay of diagnosis and timely treatment to prevent further implications of the disease. In addition, prevention of the disease with strict follow-up measures with sanitation and hygiene maintenance is also essential.
Published: 2021
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21. Experiences of people with dementia and their caregivers during the COVID-19 pandemic in India: A mixed-methods study

Author: Shashidhar Komaravolu, Adelina Comas-Herrera, Chandrasekhar Kammammettu, Saadiya Hurzuk, Renuka Br, Feba Varghese, Jayeeta Rajagopalan, Priya Treesa Thomas, Faheem Arshad, Patel Vishal Ganeshbhai, Vasundharaa S Nair, Harikrishna Annam, Shah R Dhiren, Suvarna Alladi, and Rakshith Maneshwar Hoskeri
Subjects: 2019-20 coronavirus outbreak, medicine.medical_specialty, Sociology and Political Science, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), caregiving, India, HV Social pathology. Social and public welfare. Criminology, Article, RA0421 Public health. Hygiene. Preventive Medicine, Pandemic, medicine, Dementia, Humans, Limited evidence, Psychiatry, Pandemics, business.industry, SARS-CoV-2, pandemic, General Social Sciences, COVID-19, General Medicine, medicine.disease, Caregivers, business
Abstract: Background The COVID-19 pandemic has unprecedented consequences for the management of chronic diseases such as dementia. However, limited evidence exists on the condition of persons with dementia and their caregivers during the pandemic in lower-middle-income countries (LMICs). The study aimed to provide insights into the experiences of persons with dementia and their families during the early phases of the pandemic in India. Methods This study adopted a mixed-method approach. One hundred and four persons with dementia and their caregivers were evaluated via telephone using validated instruments and a semi-structured interview guide. We used the quantitative data collected to establish a baseline, whereas qualitative data were analysed thematically. Results The study revealed that persons with dementia and their caregivers experienced difficulties during the pandemic, which included worsening of behaviour, problems in accessing care, disruptions in functional activities and struggles in enforcing infection prevention contributing to caregiver distress. An important finding that emerged was the unchanging reality of caregiving for families. The relative success of the public health response to the COVID-19 pandemic contrasted with the lack of awareness and formal support for dementia. Conclusions The COVID-19 pandemic has exposed the vulnerabilities of persons with dementia and their caregivers. This calls for a collaborative reframing of medical care and public health policies to address dementia care.
Published: 2021

22. Lipoprotein(a) and Benefit of PCSK9 Inhibition in Patients With Nominally Controlled LDL Cholesterol

Author: Gregory G. Schwartz, Michael Szarek, Vera A. Bittner, Rafael Diaz, Shaun G. Goodman, J. Wouter Jukema, Ulf Landmesser, Patricio López-Jaramillo, Garen Manvelian, Robert Pordy, Michel Scemama, Peter R. Sinnaeve, Harvey D. White, Ph Gabriel Steg, P.h. Gabriel Steg, Deepak L. Bhatt, Robert A. Harrington, Andreas M. Zeiher, Pierluigi Tricoci, Matthew T. Roe, Kenneth W. Mahaffey, Jay M. Edelberg, Corinne Hanotin, Guillaume Lecorps, Angèle Moryusef, William J. Sasiela, Jean-François Tamby, Philip E. Aylward, Heinz Drexel, Peter Sinnaeve, Mirza Dilic, Renato D. Lopes, Nina N. Gotcheva, Juan-Carlos Prieto, Huo Yong, Ivan Pećin, Zeljko Reiner, Petr Ostadal, Steen Hvitfeldt Poulsen, Margus Viigimaa, Markku S. Nieminen, Nicolas Danchin, Vakhtang Chumburidze, Nikolaus Marx, Evangelos Liberopoulos, Pablo Carlos Montenegro Valdovinos, Hung-Fat Tse, Robert Gabor Kiss, Denis Xavier, Doron Zahger, Marco Valgimigli, Takeshi Kimura, Hyo Soo Kim, Sang-Hyun Kim, Andrejs Erglis, Aleksandras Laucevicius, Sasko Kedev, Khalid Yusoff, Gabriel Arturo Ramos López, Marco Alings, Sigrun Halvorsen, Roger M. Correa Flores, Rody G. Sy, Andrzej Budaj, Joao Morais, Maria Dorobantu, Yuri Karpov, Arsen D. Ristic, Terrance Chua, Jan Murin, Zlatko Fras, Anthony J. Dalby, José Tuñón, H. Asita de Silva, Emil Hagström, Christian Müller, Chern-En Chiang, Piyamitr Sritara, Sema Guneri, Alexander Parkhomenko, Kausik K. Ray, Patrick M. Moriarty, Robert Vogel, Bernard Chaitman, Sheryl F. Kelsey, Anders G. Olsson, Jean-Lucien Rouleau, Maarten L. Simoons, Karen Alexander, Chiara Meloni, Robert Rosenson, Eric J.G. Sijbrands, John H. Alexander, Luciana Armaganijan, Akshay Bagai, Maria Cecilia Bahit, J. Matthew Brennan, Shaun Clifton, Adam D. DeVore, Shalonda Deloatch, Sheila Dickey, Keith Dombrowski, Grégory Ducrocq, Zubin Eapen, Patricia Endsley, Arleen Eppinger, Robert W. Harrison, Connie Ng Hess, Mark A. Hlatky, Joseph Dedrick Jordan, Joshua W. Knowles, Bradley J. Kolls, David F. Kong, Sergio Leonardi, Linda Lillis, David J. Maron, Jill Marcus, Robin Mathews, Rajendra H. Mehta, Robert J. Mentz, Humberto Graner Moreira, Chetan B. Patel, Sabrina Bernardez Pereira, Lynn Perkins, Thomas J. Povsic, Etienne Puymirat, William Schuyler Jones, Bimal R. Shah, Matthew W. Sherwood, Kenya Stringfellow, Darin Sujjavanich, Mustafa Toma, Charlene Trotter, Sean F.P. van Diepen, Matthew D. Wilson, Andrew Tze-Kay Yan, Lilia B. Schiavi, Marcelo Garrido, Andrés F. Alvarisqueta, Sonia A. Sassone, Anselmo P. Bordonava, Alberto E. Alves De Lima, Jorge M. Schmidberg, Ernesto A. Duronto, Orlando C. Caruso, Leonardo P. Novaretto, Miguel Angel Hominal, Oscar R. Montaña, Alberto Caccavo, Oscar A. Gomez Vilamajo, Alberto J. Lorenzatti, Luis R. Cartasegna, Gustavo A. Paterlini, Ignacio J. Mackinnon, Guillermo D. Caime, Marcos Amuchastegui, Oscar Salomone, Oscar R. Codutti, Horacio O. Jure, Julio O.E. Bono, Adrian D. Hrabar, Julio A. Vallejos, Rodolfo A. Ahuad Guerrero, Federico Novoa, Cristian A. Patocchi, Cesar J. Zaidman, Maria E. Giuliano, Ricardo D. Dran, Marisa L. Vico, Gabriela S. Carnero, Pablo N. Guzman, Juan C. Medrano Allende, Daniela F. Garcia Brasca, Miguel H. Bustamante Labarta, Sebastian Nani, Eduardo D.S. Blumberg, Hugo R. Colombo, Alberto Liberman, Victorino Fuentealba, Hector L. Luciardi, Gabriel D. Waisman, Mario A. Berli, Ruben O. Garcia Duran, Horacio G. Cestari, Hugo A. Luquez, Jorge A. Giordano, Silvia S. Saavedra, Gerardo Zapata, Osvaldo Costamagna, Susana Llois, Jonathon H. Waites, Nicholas Collins, Allan Soward, Chris L.S. Hii, James Shaw, Margaret A. Arstall, John Horowitz, Daniel Ninio, James F. Rogers, David Colquhoun, Romulo E. Oqueli Flores, Philip Roberts-Thomson, Owen Raffel, Sam J. Lehman, Constantine Aroney, Steven G.M. Coverdale, Paul J. Garrahy, Gregory Starmer, Mark Sader, Patrick A. Carroll, Ronald Dick, Robert Zweiker, Uta Hoppe, Kurt Huber, Rudolf Berger, Georg Delle-Karth, Bernhard Frey, Dirk Faes, Kurt Hermans, Bruno Pirenne, Attilio Leone, Etienne Hoffer, Mathias C.M. Vrolix, Luc De Wolf, Bart Wollaert, Marc Castadot, Karl Dujardin, Christophe Beauloye, Geert Vervoort, Harry Striekwold, Carl Convens, John Roosen, Emanuele Barbato, Marc Claeys, Frank Cools, Ibrahim Terzic, Fahir Barakovic, Zlatko Midzic, Belma Pojskic, Emir Fazlibegovic, Azra Durak-Nalbantic, Mehmed Kulić, Dusko Vulic, Adis Muslibegovic, Boris Goronja, Gilmar Reis, Luciano Sousa, Jose C. Nicolau, Flavio E. Giorgeto, Ricardo P. Silva, Lilia Nigro Maia, Rafael Rech, Paulo R.F. Rossi, Maria José A.G. Cerqueira, Norberto Duda, Renato Kalil, Adrian Kormann, José Antonio M. Abrantes, Pedro Pimentel Filho, Ana Priscila Soggia, Mayler O.N. de Santos, Fernando Neuenschwander, Luiz C. Bodanese, Yorghos L. Michalaros, Freddy G. Eliaschewitz, Maria H. Vidotti, Paulo E. Leaes, Roberto V. Botelho, Sergio Kaiser, Euler Roberto F. Fernandes Manenti, Dalton B. Precoma, Jose C. Moura Jorge, Pedro Silva, Jose A. Silveira, Wladmir Saporito, Jose A. Marin Neto, Gilson S. Feitosa, Luiz Eduardo F. Ritt, Juliana A. de Souza, Fernando Costa, Weimar K.S.B. Souza, Helder J.L. Reis, Leandro Machado, José Carlos Aidar Ayoub, Georgi V. Todorov, Fedya P. Nikolov, Elena S. Velcheva, Maria L. Tzekova, Haralambi O. Benov, Stanislav L. Petranov, Haralin S. Tumbev, Nina S. Shehova-Yankova, Dimitar T. Markov, Dimitar H. Raev, Mihail N. Mollov, Kostadin N. Kichukov, Katya A. Ilieva-Pandeva, Raya Ivanova, Maryana Gospodinov, Valentina M. Mincheva, Petar V. Lazov, Bojidar I. 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Raffo, Claudia Olivares, Leonardo Nahuelpan, Humberto Montecinos, Jiyan Chen, Yugang Dong, Weijian Huang, Jianzhong Wang, Shi'An Huang, Zhuhua Yao, Xiang Li, Lan Cui, Wenhua Lin, Yuemin Sun, Jingfeng Wang, Jianping Li, Xuelian Zhang, Hong Zhu, Dandan Chen, Lan Huang, Shaohong Dong, Guohai Su, Biao Xu, Xi Su, Xiaoshu Cheng, Jinxiu Lin, Wenxia Zong, Huanming Li, Yi Feng, Dingli Xu, Xinchun Yang, Yuannan Ke, Xuefeng Lin, Zheng Zhang, Zeqi Zheng, Zhurong Luo, Yundai Chen, Chunhua Ding, Yi Zhong, Yang Zheng, Xiaodong Li, Daoquan Peng, Shuiping Zhao, Ying Li, Xuebo Liu, Meng Wei, Shaowen Liu, Yihua Yu, Baiming Qu, Weihong Jiang, Yujie Zhou, Xingsheng Zhao, Zuyi Yuan, Ying Guo, Xiping Xu, Xubo Shi, Junbo Ge, Guosheng Fu, Feng Bai, Weiyi Fang, Xiling Shou, Xiangjun Yang, Jian'An Wang, Meixiang Xiang, Yingxian Sun, Qinghua Lu, Ruiyan Zhang, Jianhua Zhu, Yizhou Xu, Zhongcai Fan, Tianchang Li, Chun Wu, Nicolas Jaramillo, Gregorio Sanchez Vallejo, Diana C. Luna Botia, Rodrigo Botero Lopez, Dora I. Molina De Salazar, Alberto J. Cadena Bonfanti, Carlos Cotes Aroca, Juan Diego Higuera, Marco Blanquicett, Sandra I. Barrera Silva, Henry J. Garcia Lozada, Julian A. Coronel Arroyo, Jose L. Accini Mendoza, Ricardo L. Fernandez Ruiz, Alvaro M. Quintero Ossa, Fernando G. Manzur Jatin, Aristides Sotomayor Herazo, Jeffrey Castellanos Parada, Rafael Suarez Arambula, Miguel A. Urina Triana, Angela M. Fernandez Trujillo, Maja Strozzi, Siniša Car, Melita Jerić, Davor Miličić, Martina Lovrić Benčić, Hrvoje Pintarić, Đeiti Prvulović, Jozica Šikić, Viktor Peršić, Dean Mileta, Kresimir Štambuk, Zdravko Babić, Vjekoslav Tomulic, Josip Lukenda, Stanka Mejic-Krstulovic, Boris Starcevic, Jindrich Spinar, David Horak, Zdenek Velicka, Josef Stasek, David Alan, Vilma Machova, Ales Linhart, Vojtech Novotny, Vladimir Kaucak, Richard Rokyta, Robert Naplava, Zdenek Coufal, Vera Adamkova, Ivo Podpera, Jiri Zizka, Zuzana Motovska, Ivana Marusincova, Premysl Svab, Petr Heinc, Jiri Kuchar, Petr Povolny, Jiri Matuska, Steen H. Poulsen, Bent Raungaard, Peter Clemmensen, Lia E. Bang, Ole May, Morten Bøttcher, Jens D. Hove, Lars Frost, Gunnar Gislason, John Larsen, Peter Betton Johansen, Flemming Hald, Peter Johansen, Jørgen Jeppesen, Tonny Nielsen, Kjeld S. Kristensen, Piotr Maria Walichiewicz, Jens D. Lomholdt, Ib C. Klausen, Peter Kaiser Nielsen, Flemming Davidsen, Lars Videbaek, Mai Soots, Veiko Vahula, Anu Hedman, Üllar Soopõld, Kaja Märtsin, Tiina Jurgenson, Arved Kristjan, Heikki Huikuri, Juhani Airaksinen Pierre Coste, Emile Ferrari, Olivier Morel, Gilles Montalescot, Jacques Machecourt, Gilles Barone-Rochette, Jacques Mansourati, Yves Cottin, Florence Leclercq, Abdelkader Belhassane, Nicolas Delarche, Franck Boccara, Franck Paganelli, Jérôme Clerc, Francois Schiele, Victor Aboyans, Vincent Probst, Jacques Berland, Thierry Lefèvre, Bernard Citron, Irakli Khintibidze, Tamaz Shaburishvili, Zurab Pagava, Ramaz Ghlonti, Zaza Lominadze, George Khabeishvili, Rayyan Hemetsberger, Kemala Edward, Ursula Rauch-Kröhnert, Matthias Stratmann, Karl-Friedrich Appel, Ekkehard Schmidt, Heyder Omran, Christoph Stellbrink, Thomas Dorsel, Emmanouil Lianopoulos, Hans Friedrich Vöhringer, Roger Marx, Andreas Zirlik, Detlev Schellenberg, Thomas Heitzer, Ulrich Laufs, Christian Werner, Stephan Gielen, Sebastian Nuding, Bernhard Winkelmann, Steffen Behrens, Karsten Sydow, Mahir Karakas, Gregor Simonis, Thomas Muenzel, Nikos Werner, Stefan Leggewie, Dirk Böcker, Rüdiger Braun-Dullaeus, Nicole Toursarkissian, Michael Jeserich, Matthias Weißbrodt, Tim Schaeufele, Joachim Weil, Heinz Völler, Johannes Waltenberger, Mohammed Natour, Susanne Schmitt, Dirk Müller-Wieland, Stephan Steiner, Lothar Heidenreich, Elmar Offers, Uwe Gremmler, Holger Killat, Werner Rieker, Sotiris Patsilinakos, Athanasios Kartalis, Athanassios Manolis, Dimitrios Sionis, Geargios Chachalis, Ioannis Skoumas, Vasilios Athyros, Panagiotis Vardas, Frangkiskos Parthenakis, John Lekakis, Apostolos Hatzitolios, Sergio R. Fausto Ovando, Juan L. Arango Benecke, Edgar R. Rodriguez De Leon, Bryan P.Y. Yan, David C.W. Siu, Tibor Turi, Bela Merkely, Imre Ungi, Geza Lupkovics, Lajos Nagy, András Katona, István Édes, Gábor Müller, Iván Horvath, Tibor Kapin, Zsolt Szigeti, József Faluközy, Mukund Kumbla, Manjinder Sandhu, Sharath Annam, Naveen Reddy Proddutur, Reddy Regella, Rajendra K. Premchand, Ajaykumar Mahajan, Sudhir Pawar, Atul D. Abhyanakar, Prafulla Kerkar, Ravishankar A. Govinda, Abraham Oomman, Dhurjati Sinha, Sachin N. Patil, Dhiman Kahali, Jitendra Sawhney, Abhijeet B. Joshi, Sanjeev Chaudhary, Pankaj Harkut, Santanu Guha, Sanjay Porwal, Srimannarayana Jujjuru, Ramesh B. Pothineni, Minguel R. Monteiro, Aziz Khan, Shamanna S. Iyengar, Jasprakash Singh Grewal, Manoj Chopda, Mahesh C. Fulwani, Aparna Patange, Patil Sachin, Vijay K. Chopra, Naresh K. Goyal, Rituparna Shinde, Gajendra V. Manakshe, Nitin Patki, Sumeet Sethi, Vengatesh Munusamy, Sunil Karnaand Sunil Thanvi, Srilakshmi Adhyapak, Chandrakant Patil, Ulhas Pandurangi, Rishabh Mathur, Jugal Gupta, Suhas Kalashetti, Ajit Bhagwat, Bagirath Raghuraman, Shiv Kumar Yerra, Prasant Bhansali, Rohidas Borse, Patil Rahul, Srihari Das, Vinay Kumar, Jabir Abdullakutty, Shireesh Saathe, Priya Palimkar, Jabir Abdullkutty, Shireesh Sathe, Shaul Atar, Michael Shechter, Morris Mosseri, Yaron Arbel, Chorin Ehud, Havakuk Ofer, Chaim Lotan, Uri Rosenschein, Amos Katz, Yaakov Henkin, Adi Francis, Marc Klutstein, Eugenia Nikolsky, Robert Zukermann, Yoav Turgeman, Majdi Halabi, Alon Marmor, Ran Kornowski, Michael Jonas, Offer Amir, Yonathan Hasin, Yoseph Rozenman, Shmuel Fuchs, Vered Zvi, Osamah Hussein, Dov Gavish, Zvi Vered, Yoseph Caraco, Mazen Elias, Naveh Tov, Efrat Wolfovitz, Michael Lishner, Nizar Elias, Giancarlo Piovaccari, Annamaria De Pellegrin, Raffaella Garbelotto, Gabriele Guardigli, Valgimigli Marco, Giovanni Licciardello, Carla Auguadro, Filippo Scalise, Claudio Cuccia, Alessandro Salvioni, Giuseppe Musumeci, Michelle Senni, Paolo Calabrò, Salvatore Novo, Pompilio Faggiano, Marco Metra, Nicoletta B. De Cesare, Sergio Berti, Claudio Cavallini, Enrico Puccioni, Marcello Galvani, Maurizio Tespili, Piermarco Piatti, Michela Palvarini, Giuseppe De Luca, Roberto Violini, Alessandro De Leo, Zoran Olivari, Pasquale Perrone Filardi, Maurizio Ferratini, Vittorio Racca, Kazuoki Dai, Yuji Shimatani, Haruo Kamiya, Kenji Ando, Yoshihiro Takeda, Yoshihiro Morino, Yoshiki Hata, Kazuo Kimura, Koichi Kishi, Ichiro Michishita, Hiroki Uehara, Toshinori Higashikata, Atsushi Hirayama, Keiji Hirooka, Yasuji Doi, Satoru Sakagami, Shuichi Taguchi, Akihiro Koike, Hiroyuki Fujinaga, Shinji Koba, Ken Kozuma, Tomohiro Kawasaki, Yujiro Ono, Masatoshi Shimizu, Yousuke Katsuda, Atsuyuki Wada, Toshiro Shinke, Junya Ako, Kenshi Fujii, Toshiyuki Takahashi, Tomohiro Sakamoto, Koichi Nakao, Yutaka Furukawa, Hiroshi Sugino, Ritsu Tamura, Toshiaki Mano, Masaaki Uematsu, Noriaki Utsu, Kashima Ito, Takuya Haraguchi, Katsuhiko Sato, Yasunori Ueda, Akira Nishibe, Kazuteru Fujimoto, Motomaru Masutani, Jung Han Yoon, Hack-Lyoung Kim, Hun Sik Park, In-Ho Chae, Moo Hyun Kim, Myung Ho Jeong, Seungwoon Rha, Chongjin Kim, Hae Young Kim, Taekjong Hong, Seung-Jea Tahk, Youngkwon Kim, Arija Busmane, Natalija Pontaga, Aldis Strelnieks, Iveta Mintale, Iveta Sime, Zaneta Petrulioniene, Roma Kavaliauskiene, Ruta Jurgaitiene, Gintare Sakalyte, Rimvydas Slapikas, Sigute Norkiene, Nerijus Misonis, Aleksandras Kibarskis, Raimondas Kubilius, Stojko Bojovski, Nensi Lozance, Aleksandar Kjovkaroski, Snezana Doncovska, Tiong Kiam Ong, Sazzli Kasim, Oteh Maskon, Balachandran Kandasamy, Houng B. Liew, Wan Mohd Izani Wan Mohamed, Armando García Castillo, Jorge Carrillo Calvillo, Pedro Fajardo Campos, Juan Carlos Núñez Fragoso, Edmundo Alfredo Bayram Llamas, Marco Antonio Alcocer Gamba, Jaime Carranza Madrigal, Luis Gerardo González Salas, Enrique López Rosas, Belinda González Díaz, Eduardo Salcido Vázquez, Alfredo Nacoud Ackar, Guillermo Antonio Llamas Esperón, Carlos Rodolfo Martínez Sánchez, María Guerrero De Leon, Rodrigo Suarez Otero, Guillermo Fanghänel Salmón, Jesús Antonio Pérez Ríos, José Angel Garza Ruíz, Robert W. Breedveld, Margriet Feenema-Aardema, Alida Borger-Van Der Burg, Pieter A.M. Hoogslag, Harry Suryapranata, Antonius Oomen, Paulus Van Haelst, Margriet Feenema-Aradema, Jacobijne J. Wiersma, Dirk Basart, Ruud M.A. Van Der Wal, Peter Zwart, Pascalle Monraats, Henricus Van Kesteren, Ioannis Karalis, Johan Jukema, Gerardus J.E. Verdel, Bart R.G. Brueren, Roland PTh Troquay, Eric P. Viergever, Nadea Y.Y. Al-Windy, Gerard L. Bartels, Jan H. Cornel, Walter R.M. 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Bravo Mannucci, Javier Heredia Landeo, Nassip C. Llerena Navarro, Yudy M. Roldan Concha, Víctor E. Rodriguez Chavez, Henry A. Anchante Hernandez, Carlos A. Zea Nunez, Walter Mogrovejo Ramos, Arthur Ferrolino, Rosa Allyn G. Sy, Louie Tirador, Generoso Matiga, Raul Martin Coching, Alisa Bernan, Gregorio Rogelio, Dante D. Morales, Edgar Tan, Dennis Jose Sulit, Adrian Wlodarczak, Krystyna Jaworska, Grzegorz Skonieczny, Lidia Pawlowicz, Pawel Wojewoda, Benita Busz-Papiez, Janusz Bednarski, Aleksander Goch, Pawel Staneta, Elzbieta Dulak, Krzysztof Saminski, Wlodzimierz Krasowski, Wanda Sudnik, Aleksander Zurakowski, Marcin Skorski, Roman Lysek, Beata Miklaszewicz, Jacek Kubica, Jan Andrzej Lipko, Edyta Kostarska-Srokosz, Marek Piepiorka, Anna Drzewiecka, Ryszard Sciborski, Arkadiusz Stasiewski, Tomasz Blicharski, Leszek Bystryk, Michal Szpajer, Marek Korol, Tomasz Czerski, Ewa Mirek-Bryniarska, Jacek Gniot, Andrzej Lubinski, Jerzy Gorny, Edward Franek, Grzegorz Raczak, Hanna Szwed, Pedro Monteiro, Jose Mesquita Bastos, Helder H. Pereira, Dinis Martins, Filipe Seixo, Carlos Mendonça, Ana Botelho, Francisca Caetano, Bogdan Minescu, Octavian Istratoaie, Dan N. Tesloianu, Gabriel Cristian, Silviu Dumitrescu, Cristian G.C. Podoleanu, Mircea C.A. Constantinescu, Cristina M. Bengus, Constantin Militaru, Doina Rosu, Irinel R. Parepa, Adrian V. Matei, Tom M. Alexandru, Mihaela Malis, Ioan Coman, Rodica Stanescu-Cioranu, Doina Dimulescu, Yury Shvarts, Olga Orlikova, Zhanna Kobalava, Olga L. Barbarash, Valentin Markov, Nadezhda Lyamina, Alexander Gordienko, Konstantin Zrazhevsky, Alexander Y. Vishnevsky, Victor Gurevich, Raisa Stryuk, Nikita V. Lomakin, Igor Bokarev, Tatiana Khlevchuk, Sergey Shalaev, Larisa Khaisheva, Petr Chizhov, Inna Viktorova, Natalya Osokina, Vladimir Shchekotov, Evgenia Akatova, Galina Chumakova, Igor Libov, Mikhail I. Voevoda, Tatyana V. Tretyakova, Evgeny Baranov, Sergey Shustov, Sergey Yakushin, Ivan Gordeev, Niiaz Khasanov, Olga Reshetko, Tatiana Sotnikova, Olga Molchanova, Konstantin Nikolaev, Liudmila Gapon, Elena Baranova, Zaur Shogenov, Elena Kosmachova, Yuriy Karpov, Anton Povzun, Liudmila Egorova, Vadim V. Tyrenko, Igor G. Ivanov, Masterov Ilya, Sergey Kanorsky, Dragan Simic, Nikola Ivanovic, Goran Davidovic, Nebojsa Tasic, Milika R. Asanin, Stevo Stojic, Svetlana R. Apostolovic, Stevan Ilic, Biljana Putnikovic Tosic, Aleksandar Stankovic, Aleksandra Arandjelovic, Slavica Radovanovic, Branislava Todic, Jovan Balinovac, Dragan V. Dincic, Petar Seferovic, Ana Karadzic, Slobodan Dodic, Sinisa Dimkovic, Tamara Jakimov, Kian-Keong Poh, Hean Yee Ong, Justin Tang I-Shing, Karol Micko, Jan Nociar, Daniel Pella, Peter Fulop, Marian Hranai, Juraj Palka, Juraj Mazur, Ivan Majercák, Andrej Dzupina, František Fazekas, Jozef Gonsorcik, Viliam Bugan, Juraj Selecky, Gabriel Kamensky, Jaroslava Strbova, Rudolf Smik, Andrej Dukat, Peter Olexa, Ivan Žuran, Janez Poklukar, Nataša Černič Šuligoj, Matija Cevc, Henry P. Cyster, Naresh Ranjith, Clive Corbett, Junaid Bayat, Ellen Makoali Makotoko, Hendrik du Toit Theron, Ilse E. Kapp, Matthys M. de V Basson, Hanlie Lottering, Dina Van Aswegen, Louis J. Van Zyl, Peter J. 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Devarapalli, Michael Koren, Harish Chandna, George Dodds, Tauqir Goraya, James Bengston, Matthew Janik, Joseph Moran, Andrew Sumner, John Kobayashi, William Davis, Shahram Yazdani, John Pasquini, Maitreya Thakkar, Amarnath Vedere, Wayne Leimbach, James Rider, Sarah fenton, Narendra Singh, Anil V. Shah, Denise Janosik, Carl Pepine, Brett Berman, Joseph Gelormini, Christopher Daniels, Kerensky Richard, Friederike Keating, Nicholas I. Kondo, Sanjay Shetty, Howard Levite, Winfried Waider, Theodore Takata, Mazen Abu-Fadel, Vipul Shah, Rahul Aggarwal, Mark Izzo, Anil Kumar, Brack Hattler, Rose Do, Chad Link, Anna Bortnick, George Kinzfogl, Arnold Ghitis, John Larry, Edward Teufel, Peter Kuhlman, Brent Mclaurin, Wenwu Zhang, Stephen Thew, Jalal Abbas, Matthew White, Othman Islam, Sumeet Subherwal, Nandkishore Ranadive, Babak Vakili, Christian Gring, David Henderson, Timothy Schuchard, Naim Farhat, Geoffrey Kline, Sharan Mahal, Jack Whitaker, Shawn Speirs, Rolf Andersen, Nizar Daboul, Phillip Horwitz, Firas Zahr, George Ponce, Zubair Jafar, Joseph Mcgarvey, Vipul Panchal, Stephen Voyce, Thomas Blok, William Sheldon, Masoud M. Azizad, Carsten Schmalfuss, Mark Picone, Robert Pederson, William Herzog, Keith Friedman, Jason Lindsey, Rosemary Nowins, Eichenlaub Timothy, Parilak Leonard, Norman Lepor, Mahfouz El Shahawy, Howard Weintraub, Anand Irimpen, Alvaro Alonso, Wade May, Daniels Christopher, Thomas Galski, Alan Chu, Freny Mody, Ebrahimi Ramin, Zachary Hodes, Joseph Rossi, Gregory Rose, James Fairlamb, Charles Lambert, Ajit Raisinghani, Antonio Abbate, George Vetrovec, Marilyn King, Charles Carey, Jaime Gerber, Liwa Younis, Hyeun Park, Mladen Vidovich, Thomas Knutson, Dennis Friedman, Fred Chaleff, Arthur Loussararian, Phillip Rozeman, Carey Kimmelstiel, Jeffrey Kuvin, Kevin Silver, Malcolm Foster, Glen Tonnessen, Andrey Espinoza, Mohamadali Amlani, Andreas Wali, Christopher Malozzi, Geert T. Jong, Clara Massey, Keattiyoat Wattanakit, Philip J. O'Donnell, Dinesh Singal, Naseem Jaffrani, Sridhar Banuru, Daniel Fisher, Mark Xenakis, Neal Perlmutter, Ravi Bhagwat, James Strader, Ronald Blonder, Ayim Akyea-Djamson, Ajay Labroo, Kwan Lee, H. John Marais, Edmund Claxton, Robert Weiss, Rohr Kathryn, Martin Berk, Peter Rossi, Parag Joshi, Amit Khera, Ajit S. Khaira, Greg Kumkumian, Steven Lupovitch, Joshua Purow, Stephen Welka, David Hoffman, Stuart Fischer, Eugene Soroka, Donald Eagerton, Samir Pancholy, Michael Ray, Norman Erenrich, Michael Farrar, Stewart Pollock, William J. French, Steve Diamantis, Douglas Guy, Lawrence Gimple, Mark Neustel, Steven Schwartz, Edward Pereira, Seals Albert, Douglas Spriggs, Janet Strain, Suneet Mittal, Anthony Vo, Majed Chane, Jason Hall, Nampalli Vijay, Kapildeo Lotun, F. Martin Lester, Ahed Nahhas, Theodore Pope, Paul Nager, Rakesh Vohra, Mukesh Sharma, Riyaz Bashir, Hinan Ahmed, Michael Berlowitz, Robert Fishberg, Robert Barrucco, Eric Yang, Michael Radin, Daniel Sporn, Dwight Stapleton, Steven Eisenberg, Joel Landzberg, Martin Mcgough, Samir Turk, Michael Schwartz, P. Sandy Sundram, Diwakar Jain, Mark Zainea, Carlos Bayron, Ronald Karlsberg, Suhail Dohad, Henry Lui, William Keen, Donald Westerhausen, Sandeep Khurana, Himanshu Agarwal, Jessica Birchem, William Penny, Mark Chang, Sherrill Murphy, John Henry, Branislav Schifferdecker, John M Gilbert, Gopal Chalavarya, Charles Eaton, John F. Schmedtje, Stuart Christenson, Imran Dotani, Douglas Denham, Alexander Macdonell, Paul Gibson, Aref Rahman, Tammam Al Joundi, Nizar Assi, Gary Conrad, Purushotham Kotha, Michael Love, Gregory Giesler, Howard Rubenstein, Dawood Gamil, Laura Akright, Justine Krawczyk, Joanne Cobler, Terry Wells, James Welker, Robert Foster, Richard Gilmore, Jay Anderson, Douglas Jacoby, Bill Harris, Geraldine Gardner, Ramprasad Dandillaya, Kishor Vora, John Kostis, John Hunter, David Laxson, Eric Ball, Flavia Egydio, Anelise Kawakami, Janaina Oliveira, Julianna Wozniak, Alexander Matthews, Caroline Ratky, Janine Valiris, Lisa Berdan, Anita Hepditch, Kirby Quintero, Tyrus Rorick, Melissa Westbrook, Andrea Pascual, Carla Rovito, Madeleine Bezault, Elodie Drouet, Tabassome Simon, Caroline Alsweiler, Anne Luyten, Julie Butters, Liddy Griffith, Michelle Shaw, Lena Grunberg, Shahidul Islam, Marie-France Brégeault, Nathalie Bougon, Douglas Faustino, Sylvie Fontecave, Judith Murphy, Melanie Verrier, null Veronique Agnetti, Dorthe Andersen, Emmy Badreddine, Mhamed Bekkouche, Cecile Bouancheau, Imane Brigui, Maddy Brocklehurst, Joseph Cianciarulo, Dawn Devaul, Szilvia Domokos, Cecile Gache, Caroline Gobillot, Severine Guillou, Jan Healy, Megan Heath, Gayatri Jaiwal, Carine Javierre, Julien Labeirie, Myriam Monier, Ulises Morales, Asmaa Mrabti, Bicky Mthombeni, Betim Okan, Lucile Smith, Jennifer Sheller, Sebastien Sopena, Valerie Pellan, Fadela Benbernou, Nafissa Bengrait, Maud Lamoureux, Katarina Kralova, Raphael Bejuit, Anthony Coulange, Christelle Berthou, Jérôme Repincay, Christelle Lorenzato, Alexis Etienne, Valerie Gouet, Virginie Loizeau, Mickael Normand, Anne Ourliac, Christelle Rondel, Antony Adamo, Pascale Beltran, Pauline Barraud, Helene Dubois-Gache, Benjamin Halle, Lamia Metwally, Maxime Mourgues, Marc Sotty, Marion Vincendet, Raluca Cotruta, Zhu Chengyue, Dominique Fournie-Lloret, Christine Morrello, Aurelie Perthuis, Patrick Picault, Isabelle Zobouyan, Helen M. Colhoun, Michael A. Dempsey, Mark A. McClanahan, Masira, and Laucevičius, Aleksandras
Subjects: Male, Acute coronary syndrome, medicine.medical_specialty, Cardiac & Cardiovascular Systems, Randomization, PCSK9 inhibitor, LOW-DENSITY-LIPOPROTEIN, Antibodies, Monoclonal, Humanized, acute coronary syndrom, Placebo, Gastroenterology, lipoprotein(a), Internal medicine, medicine, Humans, Low-density lipoprotein cholesterol, Aged, Alirocumab, RISK, low-density lipoprotein cholesterol, Science & Technology, biology, business.industry, PCSK9, PCSK9 Inhibitors, Hazard ratio, ALIROCUMAB, acute coronary syndrome, Cholesterol, LDL, Lipoprotein(a), Middle Aged, EFFICACY, medicine.disease, Cardiovascular Diseases, CARDIOVASCULAR-DISEASE, SAFETY, Cardiovascular System & Cardiology, biology.protein, Female, lipids (amino acids, peptides, and proteins), STATIN, low-density lipoprotein, cholesterol PCSK9 inhibitor, CORONARY, Cardiology and Cardiovascular Medicine, business, Life Sciences & Biomedicine, Mace
Abstract: Digital, Background Guidelines recommend nonstatin lipid-lowering agents in patients at very high risk for major adverse cardiovascular events (MACE) if low-density lipoprotein cholesterol (LDL-C) remains ≥70 mg/dL on maximum tolerated statin treatment. It is uncertain if this approach benefits patients with LDL-C near 70 mg/dL. Lipoprotein(a) levels may influence residual risk. Objectives In a post hoc analysis of the ODYSSEY Outcomes (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab) trial, the authors evaluated the benefit of adding the proprotein subtilisin/kexin type 9 inhibitor alirocumab to optimized statin treatment in patients with LDL-C levels near 70 mg/dL. Effects were evaluated according to concurrent lipoprotein(a) levels. Methods ODYSSEY Outcomes compared alirocumab with placebo in 18,924 patients with recent acute coronary syndromes receiving optimized statin treatment. In 4,351 patients (23.0%), screening or randomization LDL-C was 13.7 mg/dL or ≤13.7 mg/dL; corresponding adjusted treatment hazard ratios were 0.82 (95% CI: 0.72-0.92) and 0.89 (95% CI: 0.75-1.06), with Pinteraction = 0.43. Conclusions In patients with recent acute coronary syndromes and LDL-C near 70 mg/dL on optimized statin therapy, proprotein subtilisin/kexin type 9 inhibition provides incremental clinical benefit only when lipoprotein(a) concentration is at least mildly elevated. (ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab; NCT01663402), Ciencias Médicas y de la Salud
Published: 2021
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23. Secure File Storage using Hybrid Cryptography

Author: Gayathri Annam, Jaya Bindu Kandi, Putta Bharathi, T Anjali, and Vamsi Krishna Duggana
Subjects: Scheme (programming language), business.industry, Computer science, Cloud computing, Cryptography, Data_CODINGANDINFORMATIONTHEORY, Encryption, Upload, Encoding (memory), Data Protection Act 1998, Hardware_ARITHMETICANDLOGICSTRUCTURES, business, computer, Cloud storage, computer.programming_language, Computer network
Abstract: Security is a major concern in a wide range of applications, from cloud storage to messaging via chat. Many different approaches have also been proposed to provide data protection in the cloud, such as AES, DES, and RSA, but Existing systems often fail when only a certain form of encoding is utilised, either AES, OR DES, OR RSA depending on a consumer requirement. However, the major issue with this scheme is that each encryption is done with encryption keys, and if these keys are leaked in some manner, the entire data is destroyed, so we need a solution that can have additional security. As a result, hybrid cryptography is used in this project, in which current encryption techniques are combined with three new methods. When a user uploads data, it is divided into three sections, the first of which is encrypted with AES, the second with DES, and the third with RSA. LSB steganography is used to store the keys in the image, and the three encrypted files are stored in the cloud. Users must first recover the keys from the image before they can import all data from the server. These keys are then used to decrypt the data once more with AES, DES, and RSA. This approach increases the security of records.
Published: 2021
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24. Integration of Teleneurology within the Health System to Manage Patients of Multiple Sclerosis and Other CNS Demyelinating Disorders During COVID-19 Pandemic

Author: Manjusha G Warrier, Priya Treesa Thomas, Ravindu, Harikrishna Annam, and Manjunath Netravathi
Subjects: 2019-20 coronavirus outbreak, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), business.industry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Multiple sclerosis, MEDLINE, medicine.disease, Pandemic, medicine, Neurology (clinical), Neurology. Diseases of the nervous system, Demyelinating Disorder, business, Intensive care medicine, RC346-429, Letters to the Editor
Published: 2020

25. Unilateral Multiple Tuberous Xanthomas Mimicking Multiple Lipomatosis in Type IIa Hypercholesterolemia- A Case Report with Review

Author: K S Harshitha, Yugank Anand, Shreya D. Prabhu, K Madhuri, Vamseedhar Annam, and C J Prakash
Subjects: medicine.medical_specialty, lcsh:R5-130.5, business.industry, Lipomatosis, Medicine, iia hypercholesterolemia, business, medicine.disease, Dermatology, lcsh:General works, Tuberous xanthomas
Abstract: The term Xanthoma was derived from a Greek word “Xanthos” meaning yellow and was generally used to describe lipid deposits in the subcutaneous plane.1 They do not represent a particular disease, but are cutaneous markers for dyslipidaemia or may even arise without any underlying metabolic defect.2 Tuberous xanthomas present as yellow or reddish nodules located mainly over the extensor surface of the extremities and buttocks.1 They may be confused with lipomas. Early diagnosis and treatment may help to prevent complications such as coronary artery disease, myocardial infarction and pancreatitis.3 We here report a case of unilateral multiple tuberous xanthomas in a young lady with elevated Low density lipoprotein levels consistent with familial hypercholesterolemia Type IIa.
Published: 2020
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26. Congenital Intrinsic Duodenal Atresia (Type III) - A Rare Case Report

Author: Sahithi Tadi, T S Anisha, Vasundhara Vasundhara, Vamseedhar Annam, and Rajalaxmi Rajalaxmi
Subjects: medicine.medical_specialty, lcsh:R5-130.5, business.industry, Internal medicine, Rare case, congenital intrinsic duodenal atresia (type iii), medicine, business, medicine.disease, Gastroenterology, lcsh:General works, Duodenal atresia
Abstract: Congenital intrinsic duodenal atresia [CIDA] is one of the rare intestinal anomalies occurring in 1 in every 5000 - 10000 live births.1 Among the various types, type III is an uncommon CIDA as compared with types I and II.2 About two thirds of all congenital duodenal obstructions are intrinsic, characterized by onset of bilious vomiting occurring within 24 hrs. after birth.3 Associated anomalies are frequently seen in nearly 50% of CIDA patients.4 In this case report we describe a patient with CIDA Type 3 without any associated congenital anomalies.
Published: 2020
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27. AWARENESS OF DIABETES AND ITS COMPLICATIONS AMONG DIABETES PATIENTS AND THEIR CARE TAKERS ATTENDING A TERTIARY CARE HOSPITAL IN CHENNAI SUBURBAN AREA

Author: Annam Lakshmanan, Meenakshi Sundari Subramaniyan Natarajan, and Balaji Ramraj
Subjects: medicine.medical_specialty, business.industry, Diabetes mellitus, Family medicine, medicine, Suburban area, Tertiary care hospital, medicine.disease, business
Published: 2019
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28. Complications of Percutaneous Renal Biopsy

Author: Kimi L. Kondo, Matthew A. Brown, Aparna Annam, Jonathan Lindquist, Kristofer Schramm, and Kenaz Bakdash
Subjects: medicine.medical_specialty, medicine.diagnostic_test, business.industry, medicine.medical_treatment, Renal function, Interventional radiology, 030204 cardiovascular system & hematology, medicine.disease, 030218 nuclear medicine & medical imaging, Surgery, Review article, 03 medical and health sciences, Delayed presentation, 0302 clinical medicine, medicine, Coagulopathy, Radiology, Nuclear Medicine and imaging, Embolization, Renal biopsy, Cardiology and Cardiovascular Medicine, business, Percutaneous Renal Biopsy
Abstract: Percutaneous renal biopsy is widely used for diagnosis, prognosis, and management of nephropathies. Complications may arise after renal biopsy, most commonly in the form of bleeding. Efforts should be taken to optimize modifiable risk factors such as hypertension, thrombocytopenia, and coagulopathy prior to the procedure. Unmodifiable risk factors such as poor renal function, gender, and underlying histologic diagnosis may be used to identify high-risk patients. Delayed presentation of bleeding complications is common, and close clinical follow-up is crucial.
Published: 2019
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29. Techno-economic and life cycle analysis of different types of hydrolysis process for the production of p-Xylene

Author: Abhay Athaley, Praneeth Annam, Basudeb Saha, and Marianthi G. Ierapetritou
Subjects: business.industry, Chemistry, 020209 energy, General Chemical Engineering, Biomass, Lignocellulosic biomass, 02 engineering and technology, Raw material, Pulp and paper industry, Environmentally friendly, Computer Science Applications, Renewable energy, Hydrolysis, 020401 chemical engineering, Scientific method, 0202 electrical engineering, electronic engineering, information engineering, 0204 chemical engineering, Molten salt, business
Abstract: The need for producing renewable chemicals and fuels from lignocellulosic biomass has increased due to economic and environment reasons. However, most of the chemicals studied to date are produced using sugars, which is readily available from biomass as their starting raw materials rather than lignocellulose, which increase the minimum selling price of produced chemicals. In this work a novel one-step saccharification (combining pretreatment and hydrolysis) process of biomass using molten salt hydrates (MSHs), an inorganic salt solution, to produce sugars and further integration of the upstream process to produce p-Xylene is investigated. We compared our one-step process with reported commercial relevant dilute acid (DA) and concentrated acid (CA) processes using detailed techno-economic analysis and life cycle analysis. The production of p-Xylene using the DA process is more costly compared to the MSH and CA processes. The cost of raw materials and utilities are the two major cost factors for the MSH process. From the life cycle analysis point of view, CA perform better than MSH process, while the DA process is less environmentally friendly mainly due to high reaction temperatures and usage of steam because of the dilute nature of the process.
Published: 2019
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30. Chronological Harris hawks‐based deep LSTM classifier in wireless sensor network for aqua status prediction

Author: Satyala Narayana, Kalyanapu Srinivas, Chandanapalli Suresh Babu, and Annam Jagadeeswara Rao
Subjects: Ecology, Computer science, business.industry, Pattern recognition, Artificial intelligence, Aquatic Science, business, Wireless sensor network, Classifier (UML), Ecology, Evolution, Behavior and Systematics, Earth-Surface Processes
Published: 2021
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31. Quantitative Parameters from OCT Angiography in Patients with Diabetic Retinopathy and in Those with Only Peripheral Retinopathy Compared with Control Participants

Author: Jennifer Perais, David Wright, Calum Gray, Nicola Quinn, Radha Das, Constantinos Nicolaou, Usha Chakravarthy, Kaushik Annam, Ian S. Young, Michel M. Teussink, Ruth E Hogg, Gareth Mc Kay, Bernadette McGuiness, Rosa Dolz-Marco, Frank Kee, George Bontzos, Tunde Peto, Tom MacGillivray, Nadia K Waheed, and Timos Naskas
Subjects: medicine.medical_specialty, genetic structures, Population, Nerve fiber layer, Foveal avascular zone, Perimeter, chemistry.chemical_compound, Oct angiography, Diabetes mellitus, SDG 3 - Good Health and Well-being, Diabetic retinopathy, Ophthalmology, medicine, education, education.field_of_study, Receiver operating characteristic, business.industry, OCT angiography, Retinal, RE1-994, medicine.disease, medicine.anatomical_structure, chemistry, Retinal periphery, business, OCTA
Abstract: PurposeTo describe the differences in a range of quantitative OCT angiography (OCTA) metrics across early stages of diabetic retinopathy (DR), providing robust effect estimates as well as sensitivity and specificity.DesignCross-sectional study with population-based sampling.ParticipantsFour hundred forty-one eyes from 296 individuals: 328 control eyes (no diabetes mellitus [DM] and no DR), 55 eyes with DM and no DR, and 58 eyes with early nonproliferative DR.MethodsMultimodal retinal imaging included color fundus photography, color Optomap ultra-widefield imaging, and spectral-domain OCT (Spectralis OCT2; Heidelberg Engineering GmbH) with the OCTA module. All images were graded for the presence and severity of DR features. OCTA images were assessed manually for inclusion based on quality. Binary OCTA metrics were assessed after 3-dimensional projection artifact removal including from the nerve fiber layer vascular plexus, superficial vascular plexus (SVC), and deep vascular plexus (DVC) by Early Treatment Diabetic Retinopathy Study (ETDRS) grid, foveal avascular zone (FAZ) area, FAZ minimum and maximum diameter, perimeter length, and circularity.Main Outcome MeasuresDiabetes mellitus and DR status and presence or absence of DR in the retinal periphery.ResultsThe reduction in vessel densities in participants with DM and manifest DR compared with control participants tended to be twice that of those with DM, but no DR, compared with control participants. Some evidence of spatial heterogeneity in vessel reductions was found in those yet to develop DR, whereas those with manifest DR had significant reductions across the ETDRS grid. The FAZ perimeter and circularity were impacted most significantly by DM, and those with DR showed decreased multispectral fractal dimensions compared with control participants. Eyes with peripheral DR had reduced vessel density compared with those with DM and no DR only in the superior outer, temporal inner, and temporal outer regions in the DVC and SVC. The area under the receiver operating characteristic curve ranged between 0.48 and 0.73.ConclusionsSignificant differences in OCTA metrics can be found in those with DM before manifest DR using commercially available equipment with minimal image postprocessing. Although diagnostic performance was poor, these metrics may be useful for measuring change over time in clinical trials.
Published: 2021
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32. Biodiesel production from preutilized cooking oil using a renewable heterogeneous eggshell‐coconut pith catalyst: Process optimization and characterization

Author: S. Anuradha Jabasingh, A. Annam Renita, and Harendra Kumar
Subjects: Biodiesel, Environmental Engineering, Central composite design, Renewable Energy, Sustainability and the Environment, business.industry, Chemistry, General Chemical Engineering, Transesterification, Heterogeneous catalysis, Pulp and paper industry, Renewable energy, Biodiesel production, Environmental Chemistry, Pith, Eggshell, business, Waste Management and Disposal, General Environmental Science, Water Science and Technology
Published: 2021
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33. Treatment of Severe COVID-19 with Convalescent Plasma in Bronx, NYC

Author: Hyun Ah Yoon, Liise Anne Pirofski, Leana Serrano-Rahman, Tao Wang, Brianna J. Lally, Rohit K. Jangra, Monika Paroder, Daniel Barboto, George I. Georgiev, Nicholas C. Morano, Margarette C. Mariano, Scott J. Garforth, Xiuyi A. Yang, Jose A. Quiroz, Johanna P. Daily, Joseph M. Sweeney, Antonio Nakouzi, Karen Fehn, Avinash Malaviya, Raja Thota, Yang Li, Catalina Florez, Ryan J. Malonis, Max Lee, Ethan Laudermilch, Audrey Lee, Inessa Gendlina, Morayma Reyes Gil, Kelsie Cowman, Johanna Rivera, J. Maximilian Fels, Jason Barnhill, Jayabhargav Annam, Uzma N. Sarwar, Joan Uehlinger, Rachel Bartash, Rachelle Babb, Natalia G. Herrera, Steven C. Almo, Stephanie Allen, Reise Sample, Denise Haslwanter, Amy S. Fox, Gregory J. Krause, Robert H. Bortz, Rafael E. Ruiz, Ahmed Khokhar, Karen Tong, Kartik Chandran, Olivia Vergnolle, M. Eugenia Dieterle, Jonathan R. Lai, Ariella Applebaum, Ariel S. Wirchnianski, and Y. Goldstein
Subjects: Male, 0301 basic medicine, Antibodies, Viral, medicine.disease_cause, 0302 clinical medicine, Hospital Mortality, skin and connective tissue diseases, Coronavirus, Aged, 80 and over, Infectious disease, Univariate analysis, biology, Age Factors, General Medicine, Middle Aged, Titer, Treatment Outcome, 030220 oncology & carcinogenesis, Spike Glycoprotein, Coronavirus, Medicine, Female, Antibody, Research Article, Adult, musculoskeletal diseases, medicine.medical_specialty, Immunoglobulins, Lower risk, Article, 03 medical and health sciences, Internal medicine, medicine, Humans, Propensity Score, Adverse effect, COVID-19 Serotherapy, Aged, Retrospective Studies, SARS-CoV-2, business.industry, Immunization, Passive, COVID-19, Retrospective cohort study, Oxygenation, Antibodies, Neutralizing, 030104 developmental biology, Ageing, Propensity score matching, biology.protein, New York City, business, Body mass index
Abstract: Convalescent plasma with severe acute respiratory disease coronavirus 2 (SARS-CoV-2) antibodies (CCP) may hold promise as treatment for Coronavirus Disease 2019 (COVID-19). We compared the mortality and clinical outcome of patients with COVID-19 who received 200mL of CCP with a Spike protein IgG titer ≥1:2,430 (median 1:47,385) within 72 hours of admission to propensity score-matched controls cared for at a medical center in the Bronx, between April 13 to May 4, 2020. Matching criteria for controls were age, sex, body mass index, race, ethnicity, comorbidities, week of admission, oxygen requirement, D-dimer, lymphocyte counts, corticosteroids, and anticoagulation use. There was no difference in mortality or oxygenation between CCP recipients and controls at day 28. When stratified by age, compared to matched controls, CCP recipients
Published: 2021
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34. Performance Evaluation of Adsorption Refrigeration System Using Different Working Pairs

Author: Bukke Kiran Naik, Ramakrishna Konijeti, Abhishek Dasore, and Surya Prakash Rao Annam
Subjects: Work (thermodynamics), Materials science, business.industry, Refrigeration, Cooling capacity, Ozone depletion potential, Refrigerant, chemistry.chemical_compound, Adsorption, chemistry, Waste heat, medicine, Process engineering, business, Activated carbon, medicine.drug
Abstract: Adsorption refrigeration system has attained intrigue in the field of refrigeration and air-conditioning due to its potential in applying available low-grade energy (waste heat from tail pipes of automobiles and solar heat) leading to savings in energy requirements and no ozone depletion potential (ODP) and global warming potential (GWP) emissions. The objective of the present work is to assess the performance of various adsorbents like activated carbon, silica gel and zeolite with methanol or water as refrigerants in an adsorption refrigeration system with respect to cycle time. Also, a mathematical model is proposed from first principles to probe the impact of adsorption and desorption temperatures on the adsorption cycle performance. This work enables us to determine the optimal adsorbent and refrigerant working pair based on the available waste heat temperature and refrigeration capacity theoretically. The results obtained are contrasted with the empirical data from the issued reports and are found to be in a reasonable agreement.
Published: 2021
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35. Periodontal dysbiosis associates with reduced CSF Aβ42 in cognitively normal elderly

Author: Smruti Pushalkar, Patricia Corby, Deepthi Gulivindala, Angela R. Kamer, Kumar Raghava Chowdary Annam, Yi Li, Deepak Saxena, Karla V. Ballman, Henrik Zetterberg, Lidia Glodzik, Mony J. de Leon, Kaj Blennow, and Tracy Butler
Subjects: Down syndrome, Amyloid, Amyloid beta, 03 medical and health sciences, 0302 clinical medicine, Cerebrospinal fluid, P‐tau, oral bacterial dysbiosis, medicine, RC346-429, CSF biomarkers, periodontitis, 030304 developmental biology, Periodontitis, 0303 health sciences, biology, business.industry, Amyloidosis, RC952-954.6, amyloid, Alzheimer's disease, medicine.disease, infection, 16S rRNA sequencing, 3. Good health, Psychiatry and Mental health, normal aging, Geriatrics, Immunology, biology.protein, Biomarker (medicine), Neurology. Diseases of the nervous system, Cerebrospinal Fluid Biomarkers, Neurology (clinical), business, Dysbiosis, 030217 neurology & neurosurgery, Research Article
Abstract: Introduction Periodontal disease is a chronic, inflammatory bacterial dysbiosis that is associated with both Alzheimer's disease (AD) and Down syndrome. Methods A total of 48 elderly cognitively normal subjects were evaluated for differences in subgingival periodontal bacteria (assayed by 16S rRNA sequencing) between cerebrospinal fluid (CSF) biomarker groups of amyloid and neurofibrillary pathology. A dysbiotic index (DI) was defined at the genus level as the abundance ratio of known periodontal bacteria to healthy bacteria. Analysis of variance/analysis of covariance (ANOVA/ANCOVA), linear discriminant effect‐size analyses (LEfSe) were used to determine the bacterial genera and species differences between the CSF biomarker groups. Results At genera and species levels, higher subgingival periodontal dysbiosis was associated with reduced CSF amyloid beta (Aβ)42 (P = 0.02 and 0.01) but not with P‐tau. Discussion We show a selective relationship between periodontal disease bacterial dysbiosis and CSF biomarkers of amyloidosis, but not for tau. Further modeling is needed to establish the direct link between oral bacteria and Aβ.
Published: 2021
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36. Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial

Author: Kausik K Ray, Helen M Colhoun, Michael Szarek, Marie Baccara-Dinet, Deepak L Bhatt, Vera A Bittner, Andrzej J Budaj, Rafael Diaz, Shaun G Goodman, Corinne Hanotin, Robert A Harrington, J Wouter Jukema, Virginie Loizeau, Renato D Lopes, Angèle Moryusef, Jan Murin, Robert Pordy, Arsen D Ristic, Matthew T Roe, José Tuñón, Harvey D White, Andreas M Zeiher, Gregory G Schwartz, Philippe Gabriel Steg, Gregory G. Schwartz, Ph. Gabriel Steg, Deepak L. Bhatt, Vera A. Bittner, Shaun G. Goodman, Robert A. Harrington, J. Wouter Jukema, Harvey D. White, Andreas M. Zeiher, Pierluigi Tricoci, Matthew T. Roe, Kenneth W. Mahaffey, Jay M. Edelberg, Guillaume Lecorps, William J. Sasiela, Jean-François Tamby, Philip E. Aylward, Heinz Drexel, Peter Sinnaeve, Mirza Dilic, Renato D. Lopes, Nina N. Gotcheva, Juan-Carlos Prieto, Huo Yong, Patricio López-Jaramillo, Ivan Pećin, Zeljko Reiner, Petr Ostadal, Margus Viigimaa, Markku S. Nieminen, Vakhtang Chumburidze, Nikolaus Marx, Nicolas Danchin, Evangelos Liberopoulos, Pablo Carlos Montenegro Valdovinos, Hung-Fat Tse, Robert Gabor Kiss, Denis Xavier, Doron Zahger, Marco Valgimigli, Takeshi Kimura, Hyo Soo Kim, Sang-Hyun Kim, Andrejs Erglis, Aleksandras Laucevicius, Sasko Kedev, Khalid Yusoff, Gabriel Arturo Ramos López, Marco Alings, Sigrun Halvorsen, Roger M. Correa Flores, Andrzej Budaj, Joao Morais, Maria Dorobantu, Yuri Karpov, Arsen D. Ristic, Terrance Chua, Zlatko Fras, Anthony J. Dalby, H. Asita de Silva, Emil Hagström, Ulf Landmesser, Chern-En Chiang, Piyamitr Sritara, Sema Guneri, Alexander Parkhomenko, Kausik K. Ray, Patrick M. Moriarty, Robert Vogel, Bernard Chaitman, Sheryl F. Kelsey, Anders G. Olsson, Jean-Lucien Rouleau, Maarten L. Simoons, Karen Alexander, Chiara Meloni, Robert Rosenson, Eric J.G. Sijbrands, John H. Alexander, Luciana Armaganijan, Akshay Bagai, Maria Cecilia Bahit, J. Matthew Brennan, Shaun Clifton, Adam D. DeVore, Shalonda Deloatch, Sheila Dickey, Keith Dombrowski, Grégory Ducrocq, Zubin Eapen, Patricia Endsley, Arleen Eppinger, Robert W. Harrison, Connie Ng Hess, Mark A. Hlatky, Joseph Dedrick Jordan, Joshua W. Knowles, Bradley J. Kolls, David F. Kong, Sergio Leonardi, Linda Lillis, David J. Maron, Jill Marcus, Robin Mathews, Rajendra H. Mehta, Robert J. Mentz, Humberto Graner Moreira, Chetan B. Patel, Sabrina Bernardez-Pereira, Lynn Perkins, Thomas J. Povsic, Etienne Puymirat, William Schuyler Jones, Bimal R. Shah, Matthew W. Sherwood, Kenya Stringfellow, Darin Sujjavanich, Mustafa Toma, Charlene Trotter, Sean Van Diepen, Matthew D. Wilson, Andrew T. Yan, Lilia B. Schiavi, Marcelo Garrido, Andrés F. Alvarisqueta, Sonia A. Sassone, Anselmo P. Bordonava, Alberto E. Alves De Lima, Jorge M. Schmidberg, Ernesto A. Duronto, Orlando C. Caruso, Leonardo P. Novaretto, Miguel Angel Hominal, Oscar R. Montaña, Alberto Caccavo, Oscar A. Gomez Vilamajo, Alberto J. Lorenzatti, Luis R. 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E, Gonzalez Diaz, B, Salcido Vazquez, E, Nacoud Ackar, A, Llamas Esperon, G, Martinez Sanchez, C, Guerrero De Leon, M, Suarez Otero, R, Fanghanel Salmon, G, Perez Rios, J, Garza Ruiz, J, Breedveld, R, Feenema-Aardema, M, Borger-Van Der Burg, A, Hoogslag, P, Suryapranata, H, Oomen, A, Van Haelst, P, Wiersma, J, Basart, D, Van Der Wal, R, Zwart, P, Monraats, P, Van Kesteren, H, Karalis, I, Verdel, G, Brueren, B, Troquay, R, Viergever, E, Al-Windy, N, Bartels, G, Cornel, J, Hermans, W, Herrman, J, Bos, R, Groutars, R, Van Der Zwaan, C, Kaplan, R, Lionarons, R, Ronner, E, Groenemeijer, B, Bronzwaer, P, Liem, A, Rensing, B, Bokern, M, Nijmeijer, R, Hersbach, F, Willems, F, Gosselink, A, Rasoul, S, Elliott, J, Wilkins, G, Fisher, R, Scott, D, Hart, H, Stewart, R, Harding, S, Ternouth, I, Fisher, N, Wilson, S, Aitken, D, Anscombe, R, Davidson, L, Tomala, T, Nygard, O, Sparby, J, Andersen, K, Gullestad, L, Jortveit, J, Munk, P, Singsaas, E, Hurtig, U, Calderon Ticona, J, Durand Velasquez, J, Negron Miguel, S, Sanabria Perez, E, Carrion Chambilla, J, Chavez Ayala, C, Castillo Leon, R, Vargas Gonzales, R, Hernandez Zuniga, J, Camacho Cosavalente, L, Bravo Mannucci, J, Heredia Landeo, J, Llerena Navarro, N, Roldan Concha, Y, Rodriguez Chavez, V, Anchante Hernandez, H, Zea Nunez, C, Mogrovejo Ramos, W, Ferrolino, A, Sy, R, Tirador, L, Matiga, G, Coching, R, Bernan, A, Rogelio, G, Morales, D, Tan, E, Sulit, D, Wlodarczak, A, Jaworska, K, Skonieczny, G, Pawlowicz, L, Wojewoda, P, Busz-Papiez, B, Bednarski, J, Goch, A, Staneta, P, Dulak, E, Saminski, K, Krasowski, W, Sudnik, W, Zurakowski, A, Skorski, M, Miklaszewicz, B, Kubica, J, Andrzej Lipko, J, Kostarska-Srokosz, E, Piepiorka, M, Drzewiecka, A, Stasiewski, A, Blicharski, T, Bystryk, L, Szpajer, M, Korol, M, Czerski, T, Mirek-Bryniarska, E, Gniot, J, Lubinski, A, Gorny, J, Franek, E, Raczak, G, Szwed, H, Monteiro, P, Mesquita Bastos, J, Pereira, H, Martins, D, Seixo, F, Mendonca, C, Botelho, A, Caetano, F, Minescu, B, Istratoaie, O, Tesloianu, D, Cristian, G, Dumitrescu, S, Podoleanu, C, Constantinescu, M, Bengus, C, Militaru, C, Rosu, D, Parepa, I, Matei, A, Alexandru, T, Malis, M, Coman, I, Stanescu-Cioranu, R, Dimulescu, D, Shvarts, Y, Orlikova, O, Kobalava, Z, Barbarash, O, Markov, V, Lyamina, N, Gordienko, A, Zrazhevsky, K, Vishnevsky, A, Gurevich, V, Stryuk, R, Lomakin, N, Bokarev, I, Khlevchuk, T, Shalaev, S, Khaisheva, L, Chizhov, P, Viktorova, I, Osokina, N, Shchekotov, V, Akatova, E, Chumakova, G, Libov, I, Voevoda, M, Tretyakova, T, Baranov, E, Shustov, S, Yakushin, S, Gordeev, I, Khasanov, N, Reshetko, O, Sotnikova, T, Molchanova, O, Nikolaev, K, Gapon, L, Baranova, E, Shogenov, Z, Kosmachova, E, Povzun, A, Egorova, L, Tyrenko, V, Ivanov, I, Ilya, M, Kanorsky, S, Simic, D, Ivanovic, N, Davidovic, G, Tasic, N, Asanin, M, Stojic, S, Apostolovic, S, Ilic, S, Putnikovic Tosic, B, Stankovic, A, Arandjelovic, A, Radovanovic, S, Todic, B, Balinovac, J, Dincic, D, Seferovic, P, Karadzic, A, Dodic, S, Dimkovic, S, Jakimov, T, Poh, K, Ong, H, Tang I-Shing, J, Micko, K, Nociar, J, Pella, D, Fulop, P, Hranai, M, Palka, J, Mazur, J, Majercak, I, Dzupina, A, Fazekas, F, Gonsorcik, J, Bugan, V, Selecky, J, Kamensky, G, Strbova, J, Smik, R, Dukat, A, Zuran, I, Poklukar, J, Cernic Suligoj, N, Cevc, M, Cyster, H, Ranjith, N, Corbett, C, Bayat, J, Makotoko, E, du Toit Theron, H, Kapp, I, de V Basson, M, Lottering, H, Van Aswegen, D, Van Zyl, L, Sebastian, P, Pillay, T, Saaiman, J, Commerford, P, Cassimjee, S, Riaz, G, Ebrahim, I, Sarvan, M, Mynhardt, J, Reuter, H, Moodley, R, Vida, M, Cequier Fillat, A, Bodi Peris, V, Fuentes Jimenez, F, Marin, F, Cruz Fernandez, J, Hidalgo Urbano, R, Gil-Extremera, B, Toledo, P, Worner Diz, F, Garcia-Dorado, D, Iniguez, A, Gonzalez-Juanatey, J, Fernandez Portales, J, Civeira Murillo, F, Matas Pericas, L, Zamorano, J, De Mora Martin, M, Bruguera Cortada, J, Alonso Martin, J, Serrano Antolin, J, De Berrazueta Fernandez, J, Vazquez de Prada, J, Diaz Fernandez, J, Garcia Lledo, J, Cosin Sales, J, Botas Rodriguez, J, Gusi Tragant, G, Benedicto, A, Gonzalez-Juanatey, C, Camprubi Potau, M, Plaza Perez, I, De La Tassa, C, Loma-Osorio Rincon, P, Balaguer Recena, J, Escudier, J, Payeras, A, Alonso Orcajo, N, Valdivielso, P, Constantine, G, Haniffa, R, Tissera, N, Amarasekera, S, Ponnamperuma, C, Fernando, N, Fernando, K, Jayawardena, J, Wijeyasingam, S, Ranasinghe, G, Ekanayaka, R, Mendis, S, Senaratne, V, Mayurathan, G, Sirisena, T, Rajapaksha, A, Herath, J, Amarasena, N, Berglund, S, Rasmanis, G, Vedin, O, Witt, N, Mourtzinis, G, Nicol, P, Hansen, O, Romeo, S, Agergaard Jensen, S, Torstensson, I, Ahremark, U, Sundelin, T, Moccetti, T, Muller, C, Mach, F, Binde, R, Tsai, W, Ueng, K, Lai, W, Liu, M, Hwang, J, Yin, W, Hsieh, I, Hsieh, M, Kuo, J, Huang, T, Fang, C, Kaewsuwanna, P, Soonfuang, W, Jintapakorn, W, Sukonthasarn, A, Wongpraparut, N, Sastravaha, K, Sansanayudh, N, Kehasukcharoen, W, Piyayotai, D, Chotnoparatpat, P, Camsari, A, Kultursay, H, Mutlu, B, Ersanli, M, Demirtas, M, Kirma, C, Ural, E, Koldas, L, Karpenko, O, Prokhorov, A, Vakaluyk, I, Myshanych, H, Reshotko, D, Batushkin, V, Rudenko, L, Kovalskyi, I, Kushnir, M, Tseluyko, V, Mostovoy, Y, Stanislavchuk, M, Kyiak, Y, Karpenko, Y, Malynovsky, Y, Klantsa, A, Kutniy, O, Amosova, E, Tashchuk, V, Leshchuk, O, Rishko, M, Kopytsya, M, Yagensky, A, Vatutin, M, Bagriy, A, Barna, O, Ushakov, O, Dzyak, G, Goloborodko, B, Rudenko, A, Zheleznyy, V, Trevelyan, J, Zaman, A, Lee, K, Moriarty, A, Aggarwal, R, Clifford, P, Wong, Y, Iqbal, S, Subkovas, E, Braganza, D, Sarkar, D, Storey, R, Griffiths, H, Mcclure, S, Muthusamy, R, Smith, S, Kurian, J, Levy, T, Barr, C, Kadr, H, Gerber, R, Simaitis, A, Soran, H, Mathur, A, Brodison, A, Ayaz, M, Cheema, M, Oliver, R, Thackray, S, Mudawi, T, Rahman, G, Sultan, A, Sharman, D, Sprigings, D, Butler, R, Wilkinson, P, Lip, G, Halcox, J, Gallagher, S, Ossei-Gerning, N, Vardi, G, Baldari, D, Brabham, D, Treasure II, C, Dahl, C, Palmer, B, Wiseman, A, Puri, S, Mohart, A, Ince, C, Flores, E, Wright, S, Cheng, S, Rosenberg, M, Rogers, W, Kosinski, E, Forgosh, L, Waltman, J, Khan, M, Shoukfeh, M, Dagher, G, Cambier, P, Lieber, I, Kumar, P, East, C, Krichmar, P, Hasan, M, White, L, Knickelbine, T, Haldis, T, Gillespie, E, Amidon, T, Suh, D, Arif, I, Abdallah, M, Akhter, F, Carlson, E, D'Urso, M, El-Ahdab, F, Nelson, W, Moriarty, K, Harris, B, Cohen, S, Carter, L, Doty, D, Sabatino, K, Haddad, T, Malik, A, Rao, S, Mulkay, A, Jovin, I, Klancke, K, Malhotra, V, Devarapalli, S, Koren, M, Chandna, H, Dodds III, G, Goraya, T, Bengston, J, Janik, M, Moran, J, Sumner, A, Kobayashi, J, Davis, W, Yazdani, S, Pasquini, J, Thakkar, M, Vedere, A, Leimbach, W, Rider, J, Fenton, S, Singh, N, Shah, A, Janosik, D, Pepine, C, Berman, B, Gelormini, J, Daniels, C, Richard, K, Keating, F, Kondo, N, Shetty, S, Levite, H, Waider, W, Takata, T, Abu-Fadel, M, Shah, V, Izzo, M, Kumar, A, Hattler, B, Do, R, Link, C, Bortnick, A, Kinzfogl III, G, Ghitis, A, Larry, J, Teufel, E, Kuhlman, P, Mclaurin, B, Zhang, W, Thew, S, Abbas, J, White, M, Islam, O, Subherwal, S, Ranadive, N, Vakili, B, Gring, C, Henderson, D, Schuchard, T, Farhat, N, Kline, G, Mahal, S, Whitaker, J, Speirs, S, Andersen, R, Daboul, N, Horwitz, P, Zahr, F, Ponce, G, Jafar, Z, Mcgarvey, J, Panchal, V, Voyce, S, Blok, T, Sheldon, W, Azizad, M, Schmalfuss, C, Picone, M, Pederson, R, Herzog, W, Friedman, K, Lindsey, J, Nowins, R, Timothy, E, Leonard, P, Lepor, N, El Shahawy, M, Weintraub, H, Irimpen, A, Alonso, A, May, W, Christopher, D, Galski, T, Chu, A, Mody, F, Ramin, E, Hodes, Z, Rossi, J, Rose, G, Fairlamb, J, Lambert, C, Raisinghani, A, Abbate, A, Vetrovec, G, King, M, Carey, C, Gerber, J, Younis, L, Vidovich, M, Knutson, T, Friedman, D, Chaleff, F, Loussararian, A, Rozeman, P, Kimmelstiel, C, Kuvin, J, Silver, K, Foster, M, Tonnessen, G, Espinoza, A, Amlani, M, Wali, A, Malozzi, C, Jong, G, Massey, C, Wattanakit, K, O'Donnell, P, Singal, D, Jaffrani, N, Banuru, S, Fisher, D, Xenakis, M, Perlmutter, N, Bhagwat, R, Strader, J, Blonder, R, Akyea-Djamson, A, Labroo, A, Marais, H, Claxton, E, Weiss, R, Kathryn, R, Berk, M, Joshi, P, Khera, A, Khaira, A, Kumkumian, G, Lupovitch, S, Purow, J, Welka, S, Hoffman, D, Fischer, S, Soroka, E, Eagerton, D, Pancholy, S, Ray, M, Erenrich, N, Farrar, M, Pollock, S, French, W, Diamantis, S, Guy, D, Gimple, L, Neustel, M, Schwartz, S, Pereira, E, Albert, S, Spriggs, D, Strain, J, Mittal, S, Vo, A, Chane, M, Hall, J, Vijay, N, Lotun, K, Lester, F, Nahhas, A, Pope, T, Nager, P, Vohra, R, Sharma, M, Bashir, R, Ahmed, H, Berlowitz, M, Fishberg, R, Barrucco, R, Yang, E, Radin, M, Sporn, D, Stapleton, D, Eisenberg, S, Landzberg, J, Mcgough, M, Turk, S, Schwartz, M, Sundram, P, Jain, D, Zainea, M, Bayron, C, Karlsberg, R, Dohad, S, Lui, H, Keen, W, Westerhausen, D, Khurana, S, Agarwal, H, Birchem, J, Penny, W, Chang, M, Murphy, S, Henry, J, Schifferdecker, B, Gilbert, J, Chalavarya, G, Eaton, C, Schmedtje, J, Christenson, S, Dotani, I, Denham, D, Macdonell, A, Gibson, P, Rahman, A, Al Joundi, T, Assi, N, Conrad, G, Kotha, P, Love, M, Giesler, G, Rubenstein, H, Gamil, D, Akright, L, Krawczyk, J, Cobler, J, Wells, T, Welker, J, Foster, R, Gilmore, R, Anderson, J, Jacoby, D, Gardner, G, Dandillaya, R, Vora, K, Kostis, J, Hunter, J, Laxson, D, Ball, E, Egydio, F, Kawakami, A, Oliveira, J, Wozniak, J, Matthews, A, Ratky, C, Valiris, J, Berdan, L, Hepditch, A, Quintero, K, Rorick, T, Westbrook, M, Pascual, A, Rovito, C, Bezault, M, Drouet, E, Simon, T, Alsweiler, C, Luyten, A, Butters, J, Griffith, L, Shaw, M, Grunberg, L, Islam, S, Bregeault, M, Bougon, N, Faustino, D, Fontecave, S, Murphy, J, Verrier, M, Agnetti, V, Andersen, D, Badreddine, E, Bekkouche, M, Bouancheau, C, Brigui, I, Brocklehurst, M, Cianciarulo, J, Devaul, D, Domokos, S, Gache, C, Gobillot, C, Guillou, S, Healy, J, Heath, M, Jaiwal, G, Javierre, C, Labeirie, J, Monier, M, Morales, U, Mrabti, A, Mthombeni, B, Okan, B, Smith, L, Sheller, J, Sopena, S, Pellan, V, Benbernou, F, Bengrait, N, Lamoureux, M, Kralova, K, Scemama, M, Bejuit, R, Coulange, A, Berthou, C, Repincay, J, Lorenzato, C, Etienne, A, Gouet, V, Normand, M, Ourliac, A, Rondel, C, Adamo, A, Beltran, P, Barraud, P, Dubois-Gache, H, Halle, B, Metwally, L, Mourgues, M, Sotty, M, Vincendet, M, Cotruta, R, Chengyue, Z, Fournie-Lloret, D, Morrello, C, Perthuis, A, Picault, P, Zobouyan, I, Dempsey, M, Mcclanahan, M, ODYSSEY OUTCOMES Comm Investigato, and Ege Üniversitesi
Subjects: Male, BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences, STATIN THERAPY, blood-glucose, Endocrinology, Diabetes and Metabolism, GUIDELINES, PCSK9, 0302 clinical medicine, Endocrinology, GENETIC-VARIANTS, Cardiovascular Disease, Diabetes Complication, Aged Antibodies, Monoclonal, Humanized / therapeutic use* Cardiovascular Diseases / blood Cardiovascular Diseases / prevention & control* Diabetes Complications / blood Diabetes Complications / prevention & control* Female Humans Male Middle Aged Substances, Clinical endpoint, Medicine, guidelines, 030212 general & internal medicine, Prediabetes, Myocardial infarction, myocardial-infarction, genetic-variants, statin therapy, risk, pcsk9, association, liraglutide, evolocumab, RISK, BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti, BLOOD-GLUCOSE, ASSOCIATION, Middle Aged, Cardiovascular Diseases, Female, Life Sciences & Biomedicine, Human, medicine.medical_specialty, Acute coronary syndrome, PCSK9 inhibitor, acute coronary syndrome, lipoprotein(a), low-density lipoprotein cholesterol, 030209 endocrinology & metabolism, Antibodies, Monoclonal, Humanized, Diabetes Complications, Endocrinology & Metabolism, 03 medical and health sciences, Diabetes mellitus, Internal medicine, Internal Medicine, Humans, Aged, Alirocumab, diabetes, PCSK9, hyperlipidemia, Science & Technology, ODYSSEY OUTCOMES Committees and Investigators, business.industry, Unstable angina, EVOLOCUMAB, medicine.disease, MYOCARDIAL-INFARCTION, LIRAGLUTIDE, Human medicine, business
Abstract: Doi, Yasuji/0000-0002-8368-0827; galvani, marcello/0000-0001-5897-667X; Gislason, Gunnar H/0000-0002-0548-402X; Taskinen, Marja-Riitta/0000-0002-6229-3588; Sherwood, Matthew/0000-0002-4305-5883; Malynovsky, Yaroslav V/0000-0002-9118-1104; Viktorova, vic-inna@mail.ru I.A./0000-0001-8728-2722; bastos, jose/0000-0002-9526-3123; Yang, Eric H/0000-0003-4889-7454; Rudenko, Anatoliy Viktorovich/0000-0003-1099-1613; Novotny, Vojtech/0000-0003-3521-9945; Nikolaev, Konstantin/0000-0003-4601-6203; Reshetko, Olga/0000-0003-3107-7636; Leonardi, Sergio/0000-0002-4800-6132; Muenzel, Thomas/0000-0001-5503-4150; Ushakov, Alexei V/0000-0002-7020-4442; Tse, Hung Fat/0000-0002-9578-7808; Podoleanu, Cristian/0000-0001-9987-2519; Raffel, Owen C/0000-0001-5470-7050; Khasanov, Niiaz/0000-0002-7760-0763; Chumakova, Galina A/0000-0002-2810-6531; Ersanli, Murat/0000-0003-1847-3087; cornel, jan hein/0000-0002-1006-2112; Abbate, Antonio/0000-0002-1930-785X; Racca, Vittorio/0000-0002-4465-3789; Urina-Triana, Miguel A/0000-0001-6003-4622; Rasputina, Lesia/0000-0003-1230-4039; Racca, Vittorio/0000-0002-4465-3789; Reis, Gilmar/0000-0002-4847-1034; Sandhu, Manjinder/0000-0003-2538-2079; Keskin, Kudret/0000-0002-9049-1530; PAREPA, IRINEL/0000-0002-7571-9015; Manakshe, Gajendra/0000-0002-4983-4271; Nicolau, Jose C/0000-0002-9680-3689; Strelnieks, Aldis/0000-0003-3493-2562; Budaj, Andrzej/0000-0002-6395-2098; Marin, Francisco/0000-0001-7246-7708; Wongpraparut, Nattawut/0000-0002-1541-3313; Yuan, Zuyi/0000-0002-4141-0298; Jeong, Myung Ho/0000-0003-2424-810X; Mostovoy, Yuriy/0000-0002-7041-1230; Pepine, Carl/0000-0002-6011-681X; Lopez-Jaramillo, Patricio/0000-0002-9122-8742; Garcia-Lledo, Alberto/0000-0002-8986-2584; Tesloianu, Nicolae-Dan/0000-0002-1007-3022; Kosmacheva, Elena/0000-0001-8600-0199; Kunz Sebba Barroso Souza, Weimar/0000-0002-1265-1930; Katz, Amos/0000-0003-0422-934X; Tunon, Jose/0000-0002-1373-0999; Acevedo, Monica/0000-0002-7989-6633; Hove, Jens/0000-0002-5600-5623; Yakushin, Sergey/0000-0001-7202-742X; Gonzalez Juanatey, Jose Ramon/0000-0001-9681-3388; Lyamina, Nadezhda/0000-0001-6939-3234; Aylward, Philip/0000-0002-5358-8552; Apostolovic, Svetlana/0000-0001-9015-297X; Airaksinen, Juhani/0000-0002-0193-568X; Nahhas, Prof. Dr. Ahmed/0000-0002-2887-8187; Barbarash, Olga/0000-0002-4642-3610, WOS: 000475553300016, PubMed: 31272931, Background After acute coronary syndrome, diabetes conveys an excess risk of ischaemic cardiovascular events. A reduction in mean LDL cholesterol to 1.4-1.8 mmol/L with ezetimibe or statins reduces cardiovascular events in patients with an acute coronary syndrome and diabetes. However, the efficacy and safety of further reduction in LDL cholesterol with an inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) after acute coronary syndrome is unknown. We aimed to explore this issue in a prespecified analysis of the ODYSSEY OUTCOMES trial of the PCSK9 inhibitor alirocumab, assessing its effects on cardiovascular outcomes by baseline glycaemic status, while also assessing its effects on glycaemic measures including risk of new-onset diabetes. Methods ODYSSEY OUTCOMES was a randomised, double-blind, placebo-controlled trial, done at 1315 sites in 57 countries, that compared alirocumab with placebo in patients who had been admitted to hospital with an acute coronary syndrome (myocardial infarction or unstable angina) 1-12 months before randomisation and who had raised concentrations of atherogenic lipoproteins despite use of high-intensity statins. Patients were randomly assigned (1: 1) to receive alirocumab or placebo every 2 weeks; randomisation was stratified by country and was done centrally with an interactive voice-response or web-response system. Alirocumab was titrated to target LDL cholesterol concentrations of 0.65-1.30 mmol/L. in this prespecified analysis, we investigated the effect of alirocumab on cardiovascular events by glycaemic status at baseline (diabetes, prediabetes, or normoglycaemia)-defined on the basis of patient history, review of medical records, or baseline HbA(1c) or fasting serum glucose-and risk of new-onset diabetes among those without diabetes at baseline. the primary endpoint was a composite of death from coronary heart disease, non-fatal myocardial infarction, fatal or non-fatal ischaemic stroke, or unstable angina requiring hospital admission. ODYSSEY OUTCOMES is registered with ClinicalTrials. gov, number NCT01663402. Findings At study baseline, 5444 patients (28.8%) had diabetes, 8246 (43.6%) had prediabetes, and 5234 (27.7%) had normoglycaemia. There were no significant differences across glycaemic categories in median LDL cholesterol at baseline (2.20-2.28 mmol/L), after 4 months' treatment with alirocumab (0.80 mmol/L), or after 4 months' treatment with placebo (2.25-2.28 mmol/L). in the placebo group, the incidence of the primary endpoint over a median of 2.8 years was greater in patients with diabetes (16.4%) than in those with prediabetes (9.2%) or normoglycaemia (8.5%); hazard ratio (HR) for diabetes versus normoglycaemia 2.09 (95% CI 1.78-2.46, p, Sanofi; Regeneron Pharmaceuticals, Sanofi and Regeneron Pharmaceuticals.
Published: 2019
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37. Correlative Analysis of Denoising Methods in Spectral Images Embedded with Different Noises

Author: Anshu Singla and Sangeetha Annam
Subjects: 050101 languages & linguistics, Computer science, business.industry, Noise (signal processing), Noise reduction, 05 social sciences, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, Shot noise, Process (computing), Hyperspectral imaging, 02 engineering and technology, Image (mathematics), Adaptive filter, Digital image, Computer Science::Computer Vision and Pattern Recognition, 0202 electrical engineering, electronic engineering, information engineering, 020201 artificial intelligence & image processing, 0501 psychology and cognitive sciences, Computer vision, Artificial intelligence, business
Abstract: Digital image is one of the primary way of communication in the present digital world. During the acquiring process, the images may become noisy. Noise reduction is a demanding task during the image analysis process without dissimilating the important features. It is the procedure of restoring the original image by discarding unwanted noises and known as Image denoising. The main intention of any noise removal technique is to completely eradicate the noise from the image, such that the resulting image is better than the original image. In this digital era, remote sensing images are widely commercial for environmental monitoring. In this study, a correlative analysis of different noise removal methods using various filters in spectral images is performed. Spectral images are introduced with different types of noise and further filters are applied to denoise the image. The performances of the methods are evaluated using benchmarks: Signal-to-Noise Ratio (SNR) and Peak Signal-to-N oise Ratio (PSNR). Experimental results demonstrate that the SNR and PSNR measures were comparatively higher for all the filters when the image is introduced with Poisson noise.
Published: 2020
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38. Psychopathology and Quality of Life in Children with Epilepsy: A Cross-Sectional Study

Author: Prahbhjot Malhi, Pratibha Singhi, and Annapoorni Annam
Subjects: medicine.medical_specialty, Cross-sectional study, Child psychopathology, 03 medical and health sciences, Epilepsy, 0302 clinical medicine, Quality of life, 030225 pediatrics, Surveys and Questionnaires, Medicine, Humans, Child, Intelligence quotient, business.industry, Public health, Mental Disorders, Regression analysis, medicine.disease, Cross-Sectional Studies, Pediatrics, Perinatology and Child Health, Quality of Life, business, 030217 neurology & neurosurgery, Psychopathology, Clinical psychology
Abstract: The study examined the relationship between psychopathology, seizure-related variables, and quality of life in children with epilepsy. Seventy-nine children with active epilepsy (Mean = 10.1 y, SD = 2.68) were consecutively recruited from the outpatient services of an advanced pediatric hospital. The Quality-of-Life in Childhood Epilepsy questionnaire and the Childhood Psychopathology Measurement Schedule (CPMS) were administered to the parents. The most compromised health-related quality of life (HRQOL) domain was the general health domain (Mean = 61.70, SD = 26.81). The mean intelligence quotient (IQ) score was 81.59 (SD = 12.34) and only 20% had IQs in the normal average range. The mean CPMS score was 7.41 (SD = 5.41). The psychopathology score and the IQ explained 43% of the variance in the total HRQOL score (F = 28.67, P = 0.0001) in the regression analysis. Childhood epilepsy is a significant public health concern and a multidisciplinary approach to management would help in addressing the multiple needs of the children with epilepsy and their families.
Published: 2020

39. Letter to the editor: Unexpected high mortality in COVID-19 and diabetic ketoacidosis

Author: Natalia Chamorro-Pareja, Julie Hoffman, Jayabhargav Annam, Sahana Parthasarathy, Preeti Kishore, and Christine Coyle
Subjects: Adult, Male, 2019-20 coronavirus outbreak, medicine.medical_specialty, Pediatrics, Letter to the editor, Coronavirus disease 2019 (COVID-19), Diabetic ketoacidosis, BMI, body mass index, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Endocrinology, Diabetes and Metabolism, Pneumonia, Viral, Article, Diabetic Ketoacidosis, Betacoronavirus, Endocrinology, DM, diabetes mellitus, Internal medicine, Pandemic, medicine, Humans, PCR, reverse-transcription polymerase chain reaction, Pandemics, Aged, biology, SARS-CoV-2, business.industry, HbA1C, hemoglobin A1C, High mortality, COVID-19, Middle Aged, biology.organism_classification, medicine.disease, ICU, intensive care unit, DKA, diabetes ketoacidosis, Female, Coronavirus Infections, business
Published: 2020
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40. Inflammatory markers are poorly predictive of clinical outcomes among hospitalized patients with COVID-19

Author: Yael Jessica Mayer, Sabrina Fowler, Fan Yang, Benjamin W. Friedman, Jinsung Kim, Carly Bass, Maykl Mosheyev, Styve Pamphile, Shira Yellin, Farnia Naeem, Rachel Borczuk, Jayabhargav Annam, and Brendan J. Barrett
Subjects: Male, medicine.medical_specialty, medicine.medical_treatment, Population, Inflammatory markers, Blood Sedimentation, Procalcitonin, Article, 03 medical and health sciences, Leukocyte Count, 0302 clinical medicine, Predictive Value of Tests, Internal medicine, White blood cell, Statistical significance, medicine, Intubation, Humans, Renal replacement therapy, Lymphocyte Count, education, Pandemics, Retrospective Studies, education.field_of_study, Inpatients, medicine.diagnostic_test, business.industry, SARS-CoV-2, COVID-19, 030208 emergency & critical care medicine, Retrospective cohort study, General Medicine, Middle Aged, Prognosis, medicine.anatomical_structure, C-Reactive Protein, ROC Curve, Erythrocyte sedimentation rate, Emergency Medicine, Female, business, Biomarkers, Follow-Up Studies
Abstract: Background Inflammatory markers are often elevated in patients with COVID-19. The objective of this study is to assess the prognostic capability of these tests in predicting clinical outcomes. Methods This was a retrospective cohort study including all patients at least 16 years old with COVID-19 who were admitted from one of five Emergency Departments between March 6th and April 4th, 2020. We included 1123 laboratory-confirmed cases of COVID-19. We analyzed white blood cell count (WBC), absolute lymphocyte count (ALC), lactate dehydrogenase (LDH), C-reactive protein (CRP), procalcitonin (PCT), D-dimer, ferritin, and erythrocyte sedimentation rate (ESR). We looked at clinical outcomes including death, the need for endotracheal intubation (ETT), the need for renal replacement therapy (RRT), and ICU admission. We report Spearman's ρ2 and statistical significance for each correlation with outcomes. We also report positive predictive value, negative predictive value, sensitivity, specificity, positive likelihood ratios, and negative likelihood ratios. Results The mean age of our patient population was 62 (SD 16). Thirty-seven percent of patients self-reported Spanish/Hispanic/Latino ethnicity, 47% reported their race as Black or African-American, and 10% reported their race as non-Hispanic white. Inter-rater reliability was 96%. There was no laboratory value that had both sensitivity and specificity of at least 0.90, or that had a positive predictive value and negative predictive value of at least 0.90, or that had likelihood ratios that could reliably predict a severe course of disease. Conclusion Inflammatory markers drawn within 48 h of arrival, though often correlated with clinical outcomes, are not individually highly predictive of which patients in a predominantly older and minority population will die or require intubation, RRT, or ICU admission., Highlights • Inflammatory markers correlate with outcomes in admitted patients with COVID-19. • Inflammatory markers have poor predictive value in admitted patients with COVID-19. • For the Emergency Department physician, obtaining inflammatory markers is not a valuable use of resources in determining disposition or prognosis.
Published: 2020

41. Parasitic Model to Describe Breakdown in Stacked-FET SOI Switches

Author: Scott Parker, Kaushik Annam, and Kathleen Muhonen
Subjects: Materials science, business.industry, 020208 electrical & electronic engineering, Silicon on insulator, 020206 networking & telecommunications, Hardware_PERFORMANCEANDRELIABILITY, 02 engineering and technology, Network topology, Capacitance, RF switch, Hardware_INTEGRATEDCIRCUITS, 0202 electrical engineering, electronic engineering, information engineering, Optoelectronics, Model development, business, Flip chip, Hardware_LOGICDESIGN
Abstract: A simple passive capacitance model has been optimized to predict breakdown in a stacked SOI FET. Specifically, as the number of FETs in a switch increases, an equivalent increase in breakdown is not seen in hardware; instead, the breakdown performance saturates as the number of stacks in the FET increases. This phenomenon is not predicted by the FET foundry model. This work is focused on FETs for RF switches in flip chip topologies. As a result of this work, the different components that contribute to off-state capacitances were also described which is important for model development and accuracy.
Published: 2020
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42. Investigation on the impacts of COVID-19 quarantine on society and environment: Preventive measures and supportive technologies

Author: Tharun Kumar Jayaraj Sivakumar, Umashankar Subramaniam, Ajayragavan Manavalanagar Vetrichelvan, Annapurna Annam, Santhosh Kumar Kumaravel, Ranjith Kumar Subramani, and Rajvikram Madurai Elavarasan
Subjects: Environmental benefits, business.industry, Preventive measures, Social distance, Control (management), Information technology, COVID-19, Review Article, Social impacts, Environmental Science (miscellaneous), Public relations, Technologies, Agricultural and Biological Sciences (miscellaneous), law.invention, Work (electrical), law, Central government, Pandemic, Quarantine, business, China, Biotechnology
Abstract: The present outbreak of the novel coronavirus SARS‐CoV‐2, epicentered in China in December 2019, has spread to many other countries. The entire humanity has a vital responsibility to tackle this pandemic and the technologies are being helpful to them to a greater extent. The purpose of the work is to precisely bring scientific and general awareness to the people all around the world who are currently fighting the war against COVID-19. It's visible that the number of people infected is increasing day by day and the medical community is tirelessly working to maintain the situation under control. Other than the negative effects caused by COVID-19, it is also equally important for the public to understand some of the positive impacts it has directly or indirectly given to society. This work emphasizes the various impacts that are created on society as well as the environment. As a special additive, some important key areas are highlighted namely, how the modernized technologies are aiding the people during the period of social distancing. Some effective technological implications carried out by both information technology and educational institutions are highlighted. There are also several steps taken by the state government and central government in each country in adopting the complete lockdown rule. These steps are taken primarily to prevent the people from COVID-19 impact. Moreover, the teachings we need to learn from the quarantine situation created to prevent further spread of this global pandemic is discussed in brief and the importance of carrying them to the future. Finally, the paper also elucidates the general preventive measures that have to be taken to prevent this deadly coronavirus, and the role of technology in this pandemic situation has also been discussed. Electronic supplementary material The online version of this article (10.1007/s13205-020-02382-3) contains supplementary material, which is available to authorized users.
Published: 2020

43. Clinical Perspective on 2019 Novel Coronavirus Pneumonia: A Systematic Review of Published Case Reports

Author: Neev Patel, Mizba Baksh, Rikinkumar S Patel, Annam Zaidi, and Jaiminkumar Patel
Subjects: covid-19 pneumonia, medicine.medical_specialty, ARDS, Pulmonology, Isolation (health care), Infectious Disease, Disease, 030204 cardiovascular system & hematology, medicine.disease_cause, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, Pandemic, Internal Medicine, medicine, Intensive care medicine, Coronavirus, interstitial pneumonia, corona pandemic, business.industry, General Engineering, covid-2019, medicine.disease, novel corona virus, Clinical trial, Pneumonia, ards, multi-viral pneumonia, business, 030217 neurology & neurosurgery
Abstract: The ongoing pandemic of 2019 novel coronavirus (2019-nCoV), which originated from Wuhan, China, has led to 68,279 deaths due to 2019-nCoV pneumonia as of May 5, 2020. We conducted a systematic review and included 16 case reports to summarize the transmission and pathology of 2019-nCoV, and clinical presentation, laboratory and imaging findings, and treatment in 2019-nCoV pneumonia. The disease is mild in most people; in some, it may progress to severe pneumonia with acute respiratory distress syndrome (ARDS). Patients with mild illness usually recover at home, with supportive care and isolation in accordance with guidelines. Patients who have moderate to severe pneumonia are usually monitored in the hospital. Although there is no definitive treatment for 2019-nCoV pneumonia so far, some antiviral drugs have shown promising results. The use of lopinavir/ritonavir and remdesivir was associated with significant clinical improvement in severe pneumonia. Nonetheless, we need more randomized clinical trials (RCTs) and treatment guidelines for developing effective management of the 2019-nCoV and improve patient outcomes by reducing mortality in high-risk patients. We also need more clinical trials and management guidelines for the effective management of 2019-nCoV pneumonia.
Published: 2020
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44. A Systematic Review of Cases of Acute Respiratory Distress Syndrome in the Coronavirus Disease 2019 Pandemic

Author: Rikinkumar S Patel, Virendrasinh Ravat, Mizba Baksh, and Annam Zaidi
Subjects: medicine.medical_specialty, ARDS, Coronavirus disease 2019 (COVID-19), hospital epidemiology, medicine.medical_treatment, sars-cov-2 (severe acute respiratory syndrome coronavirus-2), Infectious Disease, 030204 cardiovascular system & hematology, Asymptomatic, 03 medical and health sciences, 0302 clinical medicine, Pandemic, medicine, Internal Medicine, Intensive care medicine, Mechanical ventilation, business.industry, corona pandemic, General Engineering, Outbreak, Widespread Disease, medicine.disease, mortality, Clinical trial, novel corona virus, Epidemiology/Public Health, medicine.symptom, business, 030217 neurology & neurosurgery, severe acute respiratory syndrome coronavirus 2
Abstract: The outbreak of coronavirus disease 2019 (COVID-19) was declared a global pandemic after it spread to 213 countries and has the highest total number of cases worldwide About 80% of COVID-19 infections are mild or asymptomatic and never require hospitalization but about 5% of patients become critically ill and develop acute respiratory distress syndrome (ARDS) The widely used management for ARDS in COVID-19 has been in line with the standard approach, but the need to adjust the treatment protocols has been questioned based on the reports of higher mortality risk among those requiring mechanical ventilation Treatment options for this widespread disease are limited and there are no definitive therapies or vaccines until now Although some antimalarial and antiviral drugs may prove effective against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), their safety and efficacy are still under clinical trials We conducted a systematic review of case reports on ARDS in SARS-CoV-2 infection to summarize the clinical presentation, laboratory and chest imaging findings, management protocols, and outcome of ARDS in COVID-19-positive patients We need more data and established studies for the effective management of the novel SARS-CoV-2 and to reduce mortality in high-risk patients FAU - Baksh, Mizba
Published: 2020

45. PD09-05 OUTCOMES RELATED TO IMPLEMENTATION OF A FAST-TRACK, STREAMLINED PATHWAY FOR HEMATURIA REFERRALS TO THE UROLOGY DEPARTMENT AT AN ACADEMIC CENTER

Author: Allison Grant, Jay Annam, and Kara L. Watts
Subjects: Urology department, business.industry, Urology, urologic and male genital diseases, medicine.disease, medicine.icd_9_cm_classification, female genital diseases and pregnancy complications, medicine, Outpatient setting, Center (algebra and category theory), Medical emergency, Microhematuria, Fast track, business
Abstract: INTRODUCTION AND OBJECTIVE:Microhematuria (AMH) is commonly evaluated by urologists in the outpatient setting. Current pathways and guideline-discordant referrals delay evaluation and reduce effici...
Published: 2020
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46. Comparative Study of Clinical and Dermoscopic Features in Nail Psoriasis

Author: Varadraj V Pai, Annam Navya, Rakhi Ghodge, and Naphisabet Wanniang
Subjects: medicine.medical_specialty, nail psoriasis severity index, Disease duration, Dermoscopy, Disease, Nail psoriasis, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Psoriasis, lcsh:Dermatology, Medicine, skin and connective tissue diseases, integumentary system, business.industry, lcsh:RL1-803, medicine.disease, Dermatology, nail psoriasis, psoriasis area severity index, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Nail (anatomy), Nail Changes, Original Article, business
Abstract: Background, Aims, and Objectives: Nail changes have been reported in approximately 40% of psoriasis patients. Occasionally nail psoriasis may be the sole finding or the first presentation of the disease. Assessment of the nail changes associated with psoriasis can be done clinically, ultrasonographically, and most recently using a dermoscope. The aim of this study is to assess the dermoscopic features in nails of psoriasis as well as to compare the dermoscopic with the clinical findings. This study has also assessed the correlation between disease duration and the severity of skin and nail involvement. Materials and Methods: A total of 50 patients with psoriatic nail changes were recruited in the study. The psoriasis area severity index (PASI) was used to assess the severity of the disease. The nail psoriasis severity index (NAPSI) was used to determine the severity of nail involvement. The patient's nails were examined both clinically and dermoscopically. Results: Pitting was the commonest feature (84%) noted both clinically and dermoscopically. A statistically significant higher NAPSI score (P < 0.05) was obtained by a dermoscope than by clinical examination. Salmon patch and splinter hemorrhage were better visualized using a dermoscope than by clinical evaluation (P < 0.05). The duration of the disease had a strong positive correlation (R = 0.901) with the duration of nail involvement whereas there was a weak correlation between the duration of the disease and the clinical NAPSI (R = 0.23) and dermoscopic NAPSI (R = 0.28). A weak positive correlation (R = 0.3) was noted between the PASI and NAPSI scores. Conclusion: Dermoscopy of nails proved to be an efficient, supportive, easy, noninvasive method that provides a better insight into the subtle nail changes in psoriatic patients, which may have been missed clinically.
Published: 2020

47. Connect the Dots-February 2020

Author: Tesia G Kim, Nancy C. Chescheir, Julie Watters, and Annam Abbasi
Subjects: business.industry, Obstetrics and Gynecology, Library science, Medicine, business
Published: 2020

48. A Comprehensive Review on Renewable Energy Development, Challenges, and Policies of leading Indian States with an International Perspective

Author: Jens Bo Holm-Nielsen, Gm. Shafiullah, Ajayragavan Manavalanagar Vetrichelvan, Nallapaneni Manoj Kumar, Annapurna Annam, Lucian Mihet-Popa, Sanjeevikumar Padmanaban, and Rajvikram Madurai Elavarasan
Subjects: global energy scenario, General Computer Science, prospects of renewables in India, Teknologi: 500::Elektrotekniske fag: 540::Elkraft: 542 [VDP], Natural resource economics, 020209 energy, Population, 02 engineering and technology, 010501 environmental sciences, Standard of living, 01 natural sciences, Renewable energy potential, 0202 electrical engineering, electronic engineering, information engineering, General Materials Science, renewable energy barriers, energy policy in India, education, Social progress, 0105 earth and related environmental sciences, Sustainable development, Government, education.field_of_study, business.industry, Fossil fuel, Global warming, renewable energy in India, General Engineering, renewable energy potential, Renewable energy, TK1-9971, Energy policy in India, Business, Electrical engineering. Electronics. Nuclear engineering
Abstract: Clean and environment-friendly energy harvesting are of prime interest today as it is one of the key enablers in achieving the Sustainable Development Goals (SDGs) as well as accelerates social progress and enhances living standards. India, the second-most populous nation with a population of 1.353 billion, is one of the largest consumers of fossil fuels in the world which is responsible for global warming. An ever-increasing population is projected until 2050, and consequently, the energy demand in the upcoming decades will be co-accelerated by the rapid industrial growth. The Ministry of New and Renewable Energy (MNRE) with the support of National Institution for Transforming India (NITI) Aayog is working to achieve the Indian Government's target of attaining 175 GW through renewable energy resources. Many Indian states are currently increasing their renewable energy capacity in an objective to meet future energy demand. The review paper discusses in-depth about the three Indian states, namely Karnataka, Gujarat, Tamil Nadu, which pioneers the renewable energy production in India. The global energy scenario was discussed in detail with Indian contrast. Further, the barriers to the development of renewable energy generation and policies of the Indian government are discussed in detail to promote renewable energy generation throughout India as well as globally since the challenges are similar for other nations. This study analyzed various prospects of the country in renewable energy which has been done in a purpose to help the scholars, researchers, and policymakers of the nation, as it gives an insight into the present renewable energy scenario of the country.
Published: 2020
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49. Translation Embeddings for Knowledge Graph Completion in Consumer Banking Sector

Author: Rajanikanth Annam and Dongxu Shao
Subjects: Theoretical computer science, business.industry, Computer science, 02 engineering and technology, 010501 environmental sciences, 01 natural sciences, Graph, Knowledge graph, 020204 information systems, 0202 electrical engineering, electronic engineering, information engineering, Retail banking, Graph (abstract data type), business, 0105 earth and related environmental sciences
Abstract: Knowledge graphs have shown many successful applications such as recommendation. One essential challenge of knowledge graph is link prediction, which is to estimate the probability of a link between two nodes based on the existing graph. Most state-of-art models to solve this problem are built using embeddings. Experiments of previous works have been conducted on WN18 and FB15K datasets to compare the performance. However, both datasets have significantly different properties compared with financial data on which there is no benchmarking of link prediction models. In this paper, we run extensive experiments of recent models on real financial data, compare their performance deeply, and show the usage of a completed knowledge graph in consumer banking sector.
Published: 2020
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50. Impact of COVID-19 Outbreak on Travel Behaviour: Evidences from early stages of the Pandemic in India

Author: Saurabh Dandapat, Kinjal Bhattacharyya, Saysardar K, Bhargab Maitra, and Annam Sk
Subjects: Risk perception, Geography, Modal shift, Coronavirus disease 2019 (COVID-19), business.industry, Public transport, Pandemic, Outbreak, Demographic economics, Mode change, business
Abstract: The paper demonstrates the impact of COVID-19 outbreak on travel behaviour in India during the early stage. A questionnaire, consisting of five stages, was designed for collecting peoples’ responses with respect to various aspects of travel and distributed through various online modes. A total of 3,830 refined responses obtained from various cities across India were analysed using various statistical techniques. The analysis brings out several interesting findings related to the travel characteristics of people including the trend of ‘work from home’, modal shift, risk perception about travelling on different modes, and expected travel characteristics during post COVID scenario. The results clearly shows evidences of peoples’ higher risk perception for public transport, intermediate transport, and flights, modal shift in favour of personal vehicles during the initial stage, and expected delayed recovery of ridership on PT and IPT modes during post COVID era.
Published: 2020
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