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3. Cardiac allograft failure: successful use of biventricular assist device

Author

James Jaggers, Eugene E. Wolfel, Michael R. Bristow, David A. Fullerton, Frederick L. Grover, Bruce Andrea, Stephen D. Jones, JoAnn Lindenfeld, James M. Brown, and David N. Campbell

Subjects
Adult, Graft Rejection, Male, Pulmonary and Respiratory Medicine, Inotrope, Cardiotonic Agents, Pyridones, medicine.medical_treatment, Cardiac Output, Low, chemical and pharmacologic phenomena, medicine, Humans, Ultrasonography, Heart transplantation, business.industry, Isoproterenol, medicine.disease, Combined Modality Therapy, Transplantation, surgical procedures, operative, Heart failure, Anesthesia, Circulatory system, cardiovascular system, Heart Transplantation, Milrinone, Surgery, Heart-Assist Devices, Cardiology and Cardiovascular Medicine, Complication, business, medicine.drug
Abstract

Nonspecific primary allograft dysfunction is an important cause of perioperative death in cardiac transplant recipients. We report a case of severe nonspecific allograft dysfunction that was ultimately reversible after 18 days of biventricular mechanical circulatory support. Allograft recovery was echocardiographically recognized by a positive inotropic response to isoproterenol and milrinone. This case illustrates the potential for recovery of even extreme allograft dysfunction.

Published
1995

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