1. A study to better understand under-utilization of laboratory tests for antenatal care in Senegal
- Author
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Aïcha Marceline Sarr, Anna H. van’t Hoog, Pascale Ondoa, Christophe Longuet, Constance Schultsz, Souleymane Diallo, Ahmad Iyane Sow, Louis Delorme, Jean Sakandé, Winny Koster, Global Health, AII - Infectious diseases, APH - Quality of Care, APH - Personalized Medicine, and APH - Global Health
- Subjects
RNA viruses ,Bacterial Diseases ,Male ,0301 basic medicine ,Research Facilities ,Service delivery framework ,Maternal Health ,Human immunodeficiency virus (HIV) ,Disease ,Pathology and Laboratory Medicine ,medicine.disease_cause ,Treponematoses ,Health Services Accessibility ,0302 clinical medicine ,Immunodeficiency Viruses ,Health facility ,Pregnancy ,Medicine and Health Sciences ,030212 general & internal medicine ,Young adult ,Health Systems Strengthening ,Multidisciplinary ,Obstetrics and Gynecology ,Prenatal Care ,Clinical Laboratory Sciences ,Senegal ,Clinical Laboratories ,Infectious Diseases ,Research Design ,Medical Microbiology ,Viral Pathogens ,Viruses ,Medicine ,Female ,Pathogens ,Research Laboratories ,Research Article ,Neglected Tropical Diseases ,Adult ,medicine.medical_specialty ,Adolescent ,Urology ,Science ,030106 microbiology ,Sexually Transmitted Diseases ,MEDLINE ,Laboratory Tests ,Research and Analysis Methods ,Microbiology ,Young Adult ,03 medical and health sciences ,Antenatal Care ,Diagnostic Medicine ,Retroviruses ,medicine ,Humans ,Syphilis ,Microbial Pathogens ,Health Care Policy ,Genitourinary Infections ,Clinical Laboratory Techniques ,business.industry ,Lentivirus ,Organisms ,Biology and Life Sciences ,HIV ,Tropical Diseases ,medicine.disease ,Health Care ,Family medicine ,Women's Health ,business ,Government Laboratories - Abstract
Objective To better understand factors contributing to underutilization of laboratory services for health care delivery in sub-Saharan Africa, we conducted a study in Senegalese Antenatal Care clinics (ANC) and laboratories to determine the extent of underutilization, contributing factors, and bottlenecks in the cascade of care from first ANC visit, test uptake, to availability of test results and appropriate clinical management. Methods At 16 health facilities, pregnant women attending for their first ANC visit were consecutively recruited and information was prospectively collected on the request, execution, results and clinical management of seven nationally recommended laboratory screening tests for normal pregnancy: hemoglobin concentration (Hb), syphilis serology, HIV serology, determination of proteinuria (PU), determination of blood group and Rhesus factor, Emmel test to detect sickle cell disease, and glycaemia. Health facility staff were interviewed on human resource capacity, management of the ANC and the laboratory, and availability and use of guidelines. Results Of 1246 ANC attendants, 400 (32%) had complete results. Completeness varied between facilities from 0–99%. In multilevel logistic regression analysis of women nested in facilities, complete uptake was lower if women started ANC later in pregnancy; very low in rural ANC attendants who ever delivered compared to urban primigravidae (OR 0.064; 95%CI 0.00–0.52); and higher if the facility routinely recommended all seven tests. In the cascade from test request to clinical management, the most frequent bottleneck was non-execution of requested tests, while unavailability of results for executed test was uncommon (
- Published
- 2020